Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Detailed analysis of epigenetics of Wilms tumor reveals similarities to stem cells

A detailed analysis of the epigenetics - factors controlling when and in what tissues genes are expressed - of Wilms tumor reveals striking similarities to stem cells normally found in fetal kidneys. These findings by Massachusetts General Hospital Cancer Center researchers have revealed new cellular pathways that are critical for Wilms tumor development and may also apply to other pediatric cancers.

4 Jun 2010

WisTa Laboratories announces collaborative R&D agreement with Bayer Schering Pharma

WisTa Laboratories Ltd, a wholly owned subsidiary of TauRx Pharmaceuticals, announced today that they have entered a collaborative R&D agreement with Bayer Schering Pharma AG, Germany, which could redefine the way Alzheimer's disease (AD) and related disorders are currently being diagnosed and treated.

4 Jun 2010

Intellect Neurosciences receives USPTO Notice of Allowance for IN-N01 monoclonal antibody patent

Intellect Neurosciences, Inc. announced today that it has received a Notice of Allowance from the United States Patent and Trademark Office (USPTO) for a new patent related to the Company's humanized monoclonal antibody, IN-N01, being developed as a disease-modifying treatment for Alzheimer's disease and other related indications.

4 Jun 2010

Case report on clear cell ICC

Intrahepatic cholangiocarcinoma is a cancer of the bile duct in the liver. The clear cell subtype of ICC is a rare cancer; until now, only 8 cases have been reported. The number of reports is so small that a detail description of clear cell ICC is valuable.

3 Jun 2010

New oral blood-thinning drugs may have dangerous interactions when taken with prescription drugs : Study

Three new oral blood-thinning drugs nearing approval by the Food and Drug Administration are more convenient than the standard drug Coumadin® because they do not require monthly visits to adjust doses.

2 Jun 2010

ENMD-2076 demonstrates antitumor activity against murine xenograft models of CRC: Study

EntreMed, Inc., today announced the publication of preclinical results for its clinical-stage Aurora A/angiogenic kinase inhibitor, ENMD-2076, in human colorectal cancer xenograft models. The results of the study, conducted by EntreMed collaborators at the University of Colorado School of Medicine, were published in the June 1, 2010 issue of Clinical Cancer Research (Vol. 16, Issue 11).

2 Jun 2010

PET and CT colonography combination may provide suitable alternative for detecting polyps: Study

A study published in the June issue of The Journal of Nuclear Medicine shows that positron emission tomography -a molecular imaging technique-combined with computer tomography colonography may provide a suitable alternative for detecting polyps and cancer in the colon. This particular imaging method may be especially desirable for patients because it does not require sedation or bowel preparation.

2 Jun 2010

Sticky gel composed of MPEG-pDHA may help seal wounds created by surgery: Study

A compound found in sunless tanning spray may help to heal wounds following surgery, according to new results published by plastic surgeons from NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City and biomedical engineers at Cornell University in Ithaca, N.Y., where the novel compound was developed.

1 Jun 2010

University of California scientists identify new kinase that regulates cell proliferation, migration

Scientists at the University of California, San Diego have identified a previously unknown kinase that regulates cell proliferation, shape and migration, and may play a major role in the progression or metastasis of cancer cells.

1 Jun 2010

2010 Quality Index Reports on Ontario's Cancer System

Wait times for cancer radiation treatment continued their decline across Ontario during 2009, despite a more than 10 per cent increase in the number of patients receiving treatment, according to the 2010 Cancer System Quality Index report issued today.

28 May 2010

SCCA implements eHGT's eHealth Access Record Retrieval Service

eHealth Global Technologies, Inc. announced today that the Seattle Cancer Care Alliance, Seattle, WA, has successfully implemented eHGT's eHealth Access Record Retrieval Service.

28 May 2010

Bone marrow transplant cures excessive pathological grooming behavior in mice

Scientists earlier found that mice missing one of a group of core developmental genes known as the Hox genes developed an odd and rather unexpected pathology: the mutant animals groomed themselves compulsively to the point that they were removing their own hair and leaving self-inflicted open sores on their skin. Now, they've found a surprising connection between the Hoxb8 gene and the behavior that looks an awful lot like that of people with an obsessive compulsive spectrum disorder (OCD).

28 May 2010

Bio-Reference Laboratories second-quarter revenues up 27% to $110,447,000

Bio-Reference Laboratories, Inc. (Numbers in Thousands Except Per Share Data or where otherwise noted) released its second quarter, fiscal year 2010 earnings today for the three months ending April 30. The Company recorded current quarter revenues of $110,447, the best ever quarter in corporate history and an increase of 27% over the $87,183 recorded in the second quarter, fiscal year 2009.

27 May 2010

Pressure BioSciences signs CRADA with AFIP, ARP and VA

Pressure BioSciences, Inc. today announced that it has signed a Cooperative Research and Development Agreement ("CRADA") with the Armed Forces Institute of Pathology ("AFIP"), the American Registry of Pathology ("ARP"), and the Department of Veterans Affairs ("VA").

27 May 2010

Carl Zeiss launches ATLAS system for imaging of large-area specimens with nanometer resolution

Today, Carl Zeiss launches ATLAS™, a powerful hard- and software package, which, in combination with any scanning electron microscope from Carl Zeiss, enables quick and efficient imaging of large-area specimens with nanometer resolution.

27 May 2010

Study finds improvement in detection of breast cancer in mammograms over 9-year period

Researchers analyzing 2.5 million screening mammograms performed on nearly one million women found discrimination of cancerous from non-cancerous lesions improved over a nine-year period. Results of the study are published in the online edition of the journal Radiology.

27 May 2010

BioImagene launches digital pathology solutions suite in Europe

BioImagene, Inc., the leading provider of end-to-end digital pathology solutions, launched its suite of digital pathology solutions in Europe. The company will showcase these digital pathology solutions at the Woche der Pathologie Congress in Berlin, which takes place from May 27-30, 2010.

27 May 2010

New journal to focus on autoimmune disease research and development

Springer is launching a new journal Autoimmunity Highlights, an independent, international, peer-reviewed journal that publishes papers related to the diverse aspects of autoimmunity, and seeks to be a bridge between the clinic, the laboratory and the specialists who are involved in the complex world of autoimmunity diagnosis.

26 May 2010

Highlights from June 2010 issue of American Journal of Pathology

Dr. Kanneboyina Nagaraju and colleagues at the Children's National Medical Center, Washington, DC demonstrate that affected muscle may directly contribute to inflammation in muscular dystrophy. Their report can be found in the June 2010 issue of The American Journal of Pathology.

26 May 2010

HDL cholesterol can transform from good to bad actor in heart-disease process

We've all heard about the importance of raising HDL, or the so-called "good" cholesterol, and lowering LDL, or "bad" cholesterol, to improve heart health. While we've come to assume HDL cholesterol is an inherently good thing, a new study shows that for a certain group of patients, this is not always the case. The study is the first to find that a high level of the supposedly good cholesterol places a subgroup of patients at high risk for recurrent coronary events, such as chest pain, heart attack, and death.

26 May 2010

Pathology News and Research

Further Reading

Detailed analysis of epigenetics of Wilms tumor reveals similarities to stem cells

WisTa Laboratories announces collaborative R&D agreement with Bayer Schering Pharma

Intellect Neurosciences receives USPTO Notice of Allowance for IN-N01 monoclonal antibody patent

Case report on clear cell ICC

New oral blood-thinning drugs may have dangerous interactions when taken with prescription drugs : Study

ENMD-2076 demonstrates antitumor activity against murine xenograft models of CRC: Study

PET and CT colonography combination may provide suitable alternative for detecting polyps: Study

Sticky gel composed of MPEG-pDHA may help seal wounds created by surgery: Study

University of California scientists identify new kinase that regulates cell proliferation, migration

2010 Quality Index Reports on Ontario's Cancer System

SCCA implements eHGT's eHealth Access Record Retrieval Service

Bone marrow transplant cures excessive pathological grooming behavior in mice

Bio-Reference Laboratories second-quarter revenues up 27% to $110,447,000

Pressure BioSciences signs CRADA with AFIP, ARP and VA

Carl Zeiss launches ATLAS system for imaging of large-area specimens with nanometer resolution

Study finds improvement in detection of breast cancer in mammograms over 9-year period

BioImagene launches digital pathology solutions suite in Europe

New journal to focus on autoimmune disease research and development

Highlights from June 2010 issue of American Journal of Pathology

HDL cholesterol can transform from good to bad actor in heart-disease process

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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