Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

AI approach reveals possible fusion of rare diseases in COVID-19 origins

Despite extensive research, the origins of COVID-19 remain elusive. In a new study published in the KeAi journal Advances in Biomarker Sciences and Technology (ABST), an AI-driven approach was adopted to examine DNA methylation patterns at 865,859 CpG sites in blood samples from early COVID-19 patients.

10 Feb 2025

Your gut bacteria shape your health from childhood to old age, study reveals

Researchers found that gut microbiome composition is strongly linked to metabolic health across different life stages, with greater effects seen in older adults.

10 Feb 2025

New biomarker test detects early tau tangles in Alzheimer's disease

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms that litter the brain, cerebrospinal fluid and potentially blood, new research published today in Nature Medicine suggests.

10 Feb 2025

AI-driven ECG age prediction transforms early disease detection

AI-enabled ECG biological age (ECG-BA) improves disease risk classification beyond chronological age, enhancing early detection of aging-related conditions like heart disease, Alzheimer’s, and cancer.

9 Feb 2025

Study could pave the way for routine eyecare imaging as a disease screening tool

Researchers have conducted one of the largest eye studies in the world to reveal new insights into retinal thickness, highlighting its potential in the early detection of diseases like type 2 diabetes, dementia and multiple sclerosis.

5 Feb 2025

Innovative method sheds light on the proteins behind gut health

A new Weizmann Institute study identified all of the proteins in a stool sample – those from the microbiome, the human body and food – revealing the hidden secrets of the intestines and their impact on human disease

5 Feb 2025

Researchers develop model to identify tumor-fighting immune cells in lung cancer patients

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.

3 Feb 2025

Biomarker test can improve neonatal outcomes for preterm births

Preterm birth - defined as delivery before the 37th week of pregnancy - is one of the leading causes of infant deaths in the United States. Babies born prematurely are also at an increased risk of having serious health problems.

3 Feb 2025

GAP collaborates with Biomarkers of Aging Consortium to advance Alzheimer’s research

The Global Alzheimer’s Platform Foundation® (GAP) is pleased to announce a collaboration with the Biomarkers of Aging Consortium, a consortium dedicated to the developing and validating biomarkers for aging and longevity.

3 Feb 2025

Does COVID increase the risk of Alzheimer’s disease?

COVID-19, even in mild cases, is linked to changes in Alzheimer’s disease-related brain biomarkers comparable to four years of aging. This study raises concerns about long-term neurological risks and cognitive decline post-COVID.

2 Feb 2025

Study could help predict treatment response for KRASG12C-mutant non-small cell lung cancer

A new study from Moffitt Cancer Center could help doctors predict how well patients with a specific type of lung cancer will respond to new therapies.

31 Jan 2025

Alzheimer’s and Parkinson’s linked to aging brain’s failing waste disposal

New research uncovers how declining protein clearance mechanisms with age lead to Alzheimer’s, Parkinson’s, and other neurodegenerative diseases—offering hope for targeted therapies to slow or prevent these conditions.

30 Jan 2025

Shorter telomeres linked to higher risk of age-related brain diseases

People with shorter protective caps at the end of their chromosomes (called telomeres) may be more likely to develop age-related brain diseases such as stroke, dementia and late-life depression (usually diagnosed at age 60 or older), according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2025.

30 Jan 2025

Can AI recognize the signs of depression in people’s voices?

Machine learning analysis of voice recordings shows promise for detecting depression, with over 70% accuracy, improving screening in healthcare settings.

30 Jan 2025

Fluctuating cholesterol linked to higher risk of dementia in older adults

Older adults whose cholesterol changes over time may be more likely to develop dementia than people whose cholesterol is stable, regardless of the actual cholesterol level, according to a study published in the January 29, 2025, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Jan 2025