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Research provides insight into genetic mechanisms of Wilms tumor

New research from Ann & Robert H. Lurie Children's Hospital of Chicago and collaborators from other institutions provides insights into some of the genetic characteristics resulting in the development of relapse in patients with Wilms tumor (nephroblastoma), the most common type of pediatric cancer of the kidney.

24 May 2022

NIH awards first part of $30 million grant to USC team for stroke project

When administered soon after the onset of acute ischemic stroke, current approved treatments for the condition can dramatically improve patient outcomes.

24 May 2022

'Crown-like structures' surrounding breast tumors could hinder treatment response, study finds

A new study from the University of Southampton has discovered that 'crown-like structures' surrounding breast tumors in overweight and obese patients could hinder their response to therapy.

24 May 2022

Efficacy study of Paxlovid and Molnupiravir in real-world settings shows positive results

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the effectiveness of oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals, molnupiravir (Lagevrio) or nirmatrelvir/ritonavir (Paxlovid) in a real-world setting.

24 May 2022

Biologic medications used by IBD patients boost COVID-19 vaccine response

Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai.

23 May 2022

A digital twin for your immune system

In a recent study posted to the NPJ Digital Medicine journal, researchers illustrated a framework for constructing digital twins of the human immune system.

23 May 2022

Penn Medicine and CHOP announce plans with Costa Rica's CCSS for CAR T research

Penn Medicine and Children's Hospital of Philadelphia, who together pioneered the research and development of the world's first personalized cellular therapy for cancer - also known as CAR T cell therapy - have announced plans with Costa Rica's CCSS, or the Caja Costarricense de Seguro Social (Social Security Program), to facilitate CAR T research in Costa Rica.

23 May 2022

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

A new study aimed to evaluate the immunostimulatory potential of mRNA vaccines in AGS patients.

23 May 2022

Study: Nearly one-quarter of young sarcoma patients continue to use opioids after treatment completion

New analysis finds more than half of U.S. adolescents and young adults with sarcoma - a type of cancer in the bones or soft tissues - are often prescribed opioids to treat their pain.

23 May 2022

Low GI diet could help heart disease patients control their body weight and waistline

Eating low glycemic index foods promotes a healthier body shape in patients with coronary artery disease, according to a study presented at ACNAP-EuroHeartCare Congress 2022, a scientific congress of the European Society of Cardiology.

23 May 2022

Real-world vaccine effectiveness of mRNA-1273 and BNT1262b2 in immunocompromised adults

Researchers assessed the efficacy of COVID-19 vaccines in immunocompromised adults.

23 May 2022

Anti-SARS-CoV-2 titers predict COVID severity

A recent study published in the journal Viruses reported that antibody titers against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could serve as a marker for the severity of coronavirus disease 2019 (COVID-19).

22 May 2022

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Researchers determine whether mutations in the Omicron NTD influence its potential to stimulate myeloid cells and enhance inflammatory cytokine release.

22 May 2022

High air pollution may increase risk for life-threatening arrhythmias

Life-threatening arrhythmias are more common on days with highly polluted air, according to research presented today at Heart Failure 2022, a scientific congress of the European Society of Cardiology.

22 May 2022

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Scientists from St. Jude Children's Research Hospital have shown that the innate immune sensor, ZBP1, and its associated inflammatory cell death pathway, PANoptosis, are major contributors to the negative effects of interferon treatment and high interferon levels in some COVID-19 patients.

20 May 2022

Study reveals absence of structural brain changes from short-term mindfulness training

In the mid-20th century, new evidence showed that the brain could be "plastic," and that experience could create changes in the brain.

20 May 2022

ANU research could lead to better treatment options for rare, deadly bacterial infection

New research from The Australian National University could lead to better treatment options for a rare but very lethal type of bacterial infection.

20 May 2022

Discoveries may lead to new ways to treat patients with Allan-Herndon-Dudley syndrome

Two recent discoveries co-led by scientists at Cedars-Sinai may help lead to new ways to treat patients with Allan-Herndon-Dudley syndrome (AHDS), a brain development disorder that causes severe intellectual disability and problems with movement.

20 May 2022

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have identified a new molecular drug target that could result in new cancer drugs with fewer side effects.

20 May 2022

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

A blood-based tumor biomarker can predict the benefit of immunotherapy to patients with non-small cell lung cancer, according to a study published in Nature Medicine.

20 May 2022

Therapy News and Research

Research provides insight into genetic mechanisms of Wilms tumor

NIH awards first part of $30 million grant to USC team for stroke project

'Crown-like structures' surrounding breast tumors could hinder treatment response, study finds

Efficacy study of Paxlovid and Molnupiravir in real-world settings shows positive results

Biologic medications used by IBD patients boost COVID-19 vaccine response

A digital twin for your immune system

Penn Medicine and CHOP announce plans with Costa Rica's CCSS for CAR T research

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

Study: Nearly one-quarter of young sarcoma patients continue to use opioids after treatment completion

Low GI diet could help heart disease patients control their body weight and waistline

Real-world vaccine effectiveness of mRNA-1273 and BNT1262b2 in immunocompromised adults

Anti-SARS-CoV-2 titers predict COVID severity

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

High air pollution may increase risk for life-threatening arrhythmias

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Study reveals absence of structural brain changes from short-term mindfulness training

ANU research could lead to better treatment options for rare, deadly bacterial infection

Discoveries may lead to new ways to treat patients with Allan-Herndon-Dudley syndrome

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

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