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New therapy makes immunologically 'cold' tumors hot enough for immune attack

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

23 Mar 2022

FDA approves new treatment for patients with metastatic melanoma based on Johns Hopkins research

The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer.

23 Mar 2022

Smart bra can aid in early detection of breast cancer

A smart bra device developed in Nigeria can detect breast cancer early, potentially saving African women long journeys to access screening services, its inventor says.

23 Mar 2022

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

A University of Iowa neuroscience research team has identified a fundamental biochemical mechanism underlying memory storage and has linked this mechanism to cognitive deficits in mouse models of Alzheimer's Disease and Related Dementias.

23 Mar 2022

Hydrocortisone does not prevent bronchopulmonary dysplasia in preterm infants

Hydrocortisone is no more effective than placebo at preventing damage that can result from oxygen and ventilator therapy necessary to keep preterm infants alive, according to research funded by the National Institutes of Health.

23 Mar 2022

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

The National Cancer Institute, part of the National Institutes of Health, recently awarded a five-year, $ $1.9 million grant to C. Patrick Reynolds, M.D., Ph.D., director for the School of Medicine Cancer Center at the Texas Tech University Health Sciences Center.

23 Mar 2022

Researchers unravel the neural mechanisms underlying familial risk for depression

Children of mothers with clinical depression are at three times greater risk to develop depression themselves than are their low-risk peers. Researchers are working to understand the neural underpinnings of the risk, and some studies have shown altered brain processing of reward in at-risk children as young as 6.

23 Mar 2022

People who consume sugar for extended periods have increased risk of autoimmune disease

People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease.

23 Mar 2022

Umbrella analysis of the effect of renin-angiotensin-aldosterone system inhibitors on COVID-19 related outcomes

Researchers conducted an umbrella review and meta-analysis of the RAAS inhibitors' impact on COVID-19 clinical outcomes.

23 Mar 2022

New magnetic tentacle robot can reach the smallest bronchial tubes in the lung

Engineers and scientists have developed proof of concept for a robot that can reach some of the smallest bronchial tubes in the lungs - to take tissue samples or deliver cancer therapy.

23 Mar 2022

Importance of Numb-associated kinases in SARS-CoV-2 infection

A new study posted to the bioRxiv* preprint server has focussed on assessing four members of the NAK family that are associated with SARS-CoV-2 infection. These kininases could act as a target for the development of effective COVID-19 therapeutics.

23 Mar 2022

New approach could lead to quicker generation of effective, personalized cancer vaccines

Scientists have created a pipeline for identifying, prioritizing and evaluating potential tumor antigens for the fast generation of cancer vaccines, according to a report published today in eLife.

22 Mar 2022

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

Researchers evaluate antiviral effects of CD63 tetraspanin extracellular vesicles against SARS-CoV-2 and HIV-1.

22 Mar 2022

A psychedelic drug plus psychotherapy could help improve PTSD symptoms

Post-traumatic stress disorder (PTSD) affects millions of people each year, mostly survivors and witnesses of terrifying or shocking events, such as warfare, assaults or disasters. Because existing treatments don't work for everyone, new therapies are urgently needed.

22 Mar 2022

Vaccine-induced antibody response to SARS-CoV-2 Omicron variant in patients with B cell malignancies with and without active B cell-targeted therapy

Researchers have determined the effect of booster immunization on the levels of antibodies generated, against SARS-CoV-2 variants, including the Omicron strain, in cancer patients with or without active B cell-targeted therapy.

22 Mar 2022

Researchers identify a protein that protects against breast cancer growth

Researchers at Karolinska Institutet in Sweden have identified a protein that protects against breast tumor growth and that can be linked to a better prognosis in breast cancer patients.

22 Mar 2022

Early treatment of COVID-19 in high-risk children and adolescents infected with the Omicron variant of SARS-CoV-2

Researchers discussed patient features, treatment-associated process measures, and outcomes associated with early monoclonal antibody and antiviral therapy in high-risk pediatric patients infected with the SARS-CoV-2 Omicron variant.

22 Mar 2022

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

A new study investigated the interactions between SARS-CoV-2 proteins and viral and host ribonucleic acid in virus-infected cells.

22 Mar 2022

Closed Loop Medicine announces completion of precision medicine clinical trial for patients with high blood pressure

Closed Loop Medicine Ltd announced today that the last patient has completed participation in a clinical trial investigating the Company’s integrated precision care product solution for patients with hypertension.

22 Mar 2022

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

The findings of a new study suggest that a ketogenic diet - which is low in carbohydrates and protein, but high in fat - helps to kill pancreatic cancer cells when combined with a triple-drug therapy developed by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

22 Mar 2022

Therapy News and Research

New therapy makes immunologically 'cold' tumors hot enough for immune attack

FDA approves new treatment for patients with metastatic melanoma based on Johns Hopkins research

Smart bra can aid in early detection of breast cancer

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

Hydrocortisone does not prevent bronchopulmonary dysplasia in preterm infants

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

Researchers unravel the neural mechanisms underlying familial risk for depression

People who consume sugar for extended periods have increased risk of autoimmune disease

Umbrella analysis of the effect of renin-angiotensin-aldosterone system inhibitors on COVID-19 related outcomes

New magnetic tentacle robot can reach the smallest bronchial tubes in the lung

Importance of Numb-associated kinases in SARS-CoV-2 infection

New approach could lead to quicker generation of effective, personalized cancer vaccines

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

A psychedelic drug plus psychotherapy could help improve PTSD symptoms

Vaccine-induced antibody response to SARS-CoV-2 Omicron variant in patients with B cell malignancies with and without active B cell-targeted therapy

Researchers identify a protein that protects against breast cancer growth

Early treatment of COVID-19 in high-risk children and adolescents infected with the Omicron variant of SARS-CoV-2

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

Closed Loop Medicine announces completion of precision medicine clinical trial for patients with high blood pressure

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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