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Novel genetic mutations may explain link between high HDL cholesterol and reduced heart disease risk

Researchers at the University of Maryland School of Medicine have uncovered genetic mutations that may explain why people with high levels of high-density lipoprotein (HDL) cholesterol, the "good cholesterol," have a reduced risk of coronary heart disease.

7 Feb 2018

Low FODMAP diet could help IBS patients experience relief

Irritable bowel syndrome (IBS) is a collection of ailments with common symptoms such as painful bloating and diarrhea.

7 Feb 2018

Scientists find way to reduce breast cancer spread

Scientists have discovered that an amino acid called asparagine is essential for breast cancer spread, and by restricting it, cancer cells stopped invading other parts of the body in mice, according to research part-funded by Cancer Research UK and published in the journal Nature today, (Wednesday).

7 Feb 2018

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

A research team led by a biochemist at the University of California, Riverside has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl groups are added to the DNA molecule.

7 Feb 2018

Patients with multimorbidity suffer from high out-of-pocket costs

Current strategies for treating patients with several chronic diseases are putting an unnecessary financial burden on countries' health systems and individuals, a global study led by the National University of Singapore and the University of Melbourne has found.

7 Feb 2018

Study provides insights into how obesity may contribute to male infertility

A new study sheds light on how obesity may contribute to male infertility. Published in open-access journal Frontiers in Physiology, the study reports that obese men have increased levels of inflammatory markers in their seminal fluid and lower sperm quality, both of which correlate with their body mass index.

7 Feb 2018

Research could pave way for treatments to reduce risk of heart disease and stroke

The discovery of a previously unknown interaction between proteins could provide a breakthrough in the prevention of damage to healthy blood vessels.

7 Feb 2018

Women with breast cancer often mispredict future well-being after mastectomy

Women with breast cancer who underwent a mastectomy without breast reconstruction generally underestimated their future quality of life, while those who had immediate reconstruction generally overestimated it.

7 Feb 2018

New position statement for use of biosimilars to treat rheumatic diseases

Products that are "biosimilar" or interchangeable with a licensed biological product hold considerable promise for the treatment of a variety of medical conditions such as rheumatic diseases, and possibly at a reduced cost.

7 Feb 2018

Researchers discover molecule that enhances cartilage regeneration and curbs inflammation

Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? Keck School of Medicine of USC scientist Denis Evseenko, MD, PhD, has reason to be optimistic.

7 Feb 2018

Scientists find new way to kill liver cancer cells

Scientists at the University of Delaware and the University of Illinois at Chicago have found a new way to kill liver cancer cells and inhibit tumor growth. First, they silence a key cellular enzyme, and then they add a powerful drug.

7 Feb 2018

IU scientists take important step to fight against hepatitis B with 'virus-cracking' molecules

Indiana University researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer.

7 Feb 2018

New discovery could be key to stopping damage caused by inflammation in many diseases

A discovery by Queensland scientists could be the key to stopping damage caused by uncontrolled inflammation in a range of common diseases including liver disease, Alzheimer's and gout.

7 Feb 2018

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Scientists have for the first time discovered a mechanism that limits the number of "cellular janitors" in the nervous system, leading to increased risk for two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia, according to a Keck School of Medicine of USC study published today in Nature Medicine.

7 Feb 2018

Previously discarded antibiotic compounds could become life-saving drugs

Researchers are re-examining antibacterial compounds to see whether they could hold the key to fighting drug-resistant infections.

7 Feb 2018

Study accurately estimates prevalence of FASD in the United States

Researchers at University of California San Diego School of Medicine found a significant number of children across four regions in the United States were determined to have fetal alcohol spectrum disorders.

7 Feb 2018

Altered immune cell clocks may contribute to metabolic diseases in shift workers

About 15 million Americans don't have a typical nine-to-five workday, and many of these--nurses, firefighters and flight attendants, among many other professions--may see their schedule change drastically one week to the next.

7 Feb 2018

Social interaction could enhance dementia care, finds study

Increasing social interaction among people living with dementia in care homes could improve the quality of their life and save money, suggests new study.

7 Feb 2018

Nurse calls cops after new mom seeks help for depression. Right call?

Four months after having her second baby, Jessica Porten started feeling really irritable. Little things would annoy her, like her glider chair.

7 Feb 2018

Loss of coenzyme Q10 increases pre-diabetes risk

Levels of CoQ and the presence of insulin resistance were analyzed in a range of experimental laboratory settings, mouse models and samples from humans, as part of an ambitious research collaboration conducted with the University of Sydney, Victor Chang Cardiac Research Institute, Duke University School of Medicine, Garvan Institute of Medical Research, Genentech Inc. and the University of New South Wales.

7 Feb 2018

Research News and Research

Novel genetic mutations may explain link between high HDL cholesterol and reduced heart disease risk

Low FODMAP diet could help IBS patients experience relief

Scientists find way to reduce breast cancer spread

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

Patients with multimorbidity suffer from high out-of-pocket costs

Study provides insights into how obesity may contribute to male infertility

Research could pave way for treatments to reduce risk of heart disease and stroke

Women with breast cancer often mispredict future well-being after mastectomy

New position statement for use of biosimilars to treat rheumatic diseases

Researchers discover molecule that enhances cartilage regeneration and curbs inflammation

Scientists find new way to kill liver cancer cells

IU scientists take important step to fight against hepatitis B with 'virus-cracking' molecules

New discovery could be key to stopping damage caused by inflammation in many diseases

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Previously discarded antibiotic compounds could become life-saving drugs

Study accurately estimates prevalence of FASD in the United States

Altered immune cell clocks may contribute to metabolic diseases in shift workers

Social interaction could enhance dementia care, finds study

Nurse calls cops after new mom seeks help for depression. Right call?

Loss of coenzyme Q10 increases pre-diabetes risk

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