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Encapsulated Indian medicinal herb can reduce blood glucose levels in diabetic mice

Extracts of the herb Withania coagulans, or Paneer dodi, are used in traditional Indian medicine. Although some healers claim that W. coagulans can help treat diabetes, the bitter-tasting plant hasn't been studied extensively by scientists.

31 Jul 2019

Exercise may reduce artery stiffening associated with heart failure

New research suggests exercise may prevent or lessen artery stiffening associated with heart failure by limiting the buildup of unsafe chemicals around the heart.

30 Jul 2019

Clinical trial assesses efficacy and safety of thrombectomy in patients with larger strokes

Building on research results published today in JAMA Neurology showing patients with larger ischemic strokes could benefit from endovascular thrombectomy, an international, multicenter Phase III clinical trial will be starting at The University of Texas Health Science Center at Houston.

29 Jul 2019

Combination therapy could be a promising treatment for late-stage acute lymphoblastic leukemia

Acute lymphoblastic leukemia accounts for one in five adult leukemias, and is the most common pediatric cancer in the United States.

29 Jul 2019

Lymph node response to treatment can predict survival in patients with esophageal cancer

Optimal methods for predicting treatment efficacy in patients with esophageal cancer are seriously lacking. But now, researchers from Japan have found a useful alternative to existing methods for predicting patient outcomes.

29 Jul 2019

Banning tobacco sales to under 21s could have significant impacts on population health

Restricting the sale of tobacco and tobacco products for persons under the age of 21 could lead to a decline in smoking rates across the USA.

29 Jul 2019

Trial shows nor-urso as an effective treatment option for nonalcoholic fatty liver disease

A team led by Michael Trauner at MedUni Vienna's Division of Gastroenterology and Hepatology demonstrated the beneficial effect of synthetically produced bile acid with the active agent nor-ursodeoxycholic acid (nor-urso) in the hitherto incurable liver disease primary sclerosing cholangitis (PSC) around two years ago.

29 Jul 2019

HDO-antimiR could be a potent weapon to combat microRNA-related disease

MicroRNA (miRNA) is a type of RNA that plays an important role in various cellular processes and is also involved in developing defenses against pathogens. Increasing numbers of studies have indicated that certain human diseases are caused by altered expression and organization of miRNA.

27 Jul 2019

New biomimetic culture system enables more extensive testing of drugs and gene therapies

Researchers at the University of Louisville have developed an easily reproducible system that enables them to keep slices of human hearts alive for a longer period of time, allowing more extensive testing of new drugs and gene therapies.

26 Jul 2019

FDA approves first nasal glucagon therapy for treatment of severe hypoglycemia

The U.S. Food and Drug Administration today approved Baqsimi nasal powder, the first glucagon therapy approved for the emergency treatment of severe hypoglycemia that can be administered without an injection.

24 Jul 2019

Controlled stimulation of the ear canal can help reduce Parkinson's symptoms

A new study has shown that gentle, controlled stimulation of the ear canal can help reduce symptoms of Parkinson's disease.

24 Jul 2019

Common antimalarial treatment has less effect in children with severe malnutrition

Researchers have found that severe malnutrition is associated with lower exposure to the antimalarial drug lumefantrine in children treated with artemether-lumefantrine, the most common treatment, for uncomplicated falciparum malaria.

24 Jul 2019

Tailored adherence strategies needed to engage young African women in consistent PrEP use

In a study of open-label Truvada as daily pre-exposure prophylaxis (PrEP) to prevent HIV among 427 young African women and adolescent girls, 95% initiated the HIV prevention strategy, and most used PrEP for the first three months.

24 Jul 2019

Women who inherit BRCA mutations have high risk of developing cancer

Women who inherit harmful mutations in the BRCA1 or BRCA2 gene are at high risk of developing breast and ovarian cancer.

24 Jul 2019

Alzheimer's Association awards $3 million grant to support Longeveron's innovative clinical trial

The Alzheimer's Association has awarded Longeveron LLC, a Miami-based biopharmaceutical company that develops cellular therapies for aging-related diseases, a $3 million grant to be applied to the company's mesenchymal stem cell Alzheimer's research.

23 Jul 2019

Exosomes can restore health to brain cells affected by developmental disease

Like overpacked suitcases unloaded from the underbelly of a jet, molecular satchels called exosomes are continuously deployed from all cells in the body—each one brimming with an assortment of contents that another cell may unpack and use.

23 Jul 2019

Molecular action that enables cilantro to effectively delay certain seizures uncovered

Herbs, including cilantro, have a long history of use as folk medicine anticonvulsants. Until now, many of the underlying mechanisms of how the herbs worked remained unknown.

23 Jul 2019

Continuation of community-wide HIV testing could lead to reductions in new HIV cases

Continuation of community-wide HIV testing and prompt initiation of treatment as delivered in the HPTN 071 study in South Africa and Zambia could lead to substantial reductions in new HIV cases, be cost-effective, and help to achieve the UNAIDS 2030 targets, according to projections from mathematical modeling and cost-effectiveness analyses presented today at the 10th International AIDS Society Conference on HIV Science in Mexico City.

23 Jul 2019

New quantitative biomarker helps assess quality of corneal cells

Our eyes -- the windows to the soul -- need constant care, and as we age, they sometimes also need significant repair.

23 Jul 2019

Using zebrafish to discover and identify new drugs to treat spinal cord lesions

A research team led by Leonor Saúde, Principal Investigator at Instituto de Medicina Molecular, in partnership with the company Technophage, SA, has designed a simple and efficient platform that uses zebrafish to discover and identify new drugs to treat spinal cord lesions.

22 Jul 2019

Efficacy News and Research

Encapsulated Indian medicinal herb can reduce blood glucose levels in diabetic mice

Exercise may reduce artery stiffening associated with heart failure

Clinical trial assesses efficacy and safety of thrombectomy in patients with larger strokes

Combination therapy could be a promising treatment for late-stage acute lymphoblastic leukemia

Lymph node response to treatment can predict survival in patients with esophageal cancer

Banning tobacco sales to under 21s could have significant impacts on population health

Trial shows nor-urso as an effective treatment option for nonalcoholic fatty liver disease

HDO-antimiR could be a potent weapon to combat microRNA-related disease

New biomimetic culture system enables more extensive testing of drugs and gene therapies

FDA approves first nasal glucagon therapy for treatment of severe hypoglycemia

Controlled stimulation of the ear canal can help reduce Parkinson's symptoms

Common antimalarial treatment has less effect in children with severe malnutrition

Tailored adherence strategies needed to engage young African women in consistent PrEP use

Women who inherit BRCA mutations have high risk of developing cancer

Alzheimer's Association awards $3 million grant to support Longeveron's innovative clinical trial

Exosomes can restore health to brain cells affected by developmental disease

Molecular action that enables cilantro to effectively delay certain seizures uncovered

Continuation of community-wide HIV testing could lead to reductions in new HIV cases

New quantitative biomarker helps assess quality of corneal cells

Using zebrafish to discover and identify new drugs to treat spinal cord lesions

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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