Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Cerba Healthcare to acquire Canadian contract research laboratory Cirion Biopharma Research to expand bioanalytical capabilities and shorten time-to-deploy complex clinical trials

Cerba HealthCare, a leading global player in medical diagnosis, today announced it has acquired CIRION BIOPHARMA RESEARCH INC

From Cerba Research 11 Sep 2023

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Alzheimer's disease is the most common cause of dementia that affects more than 6.5 million Americans, according to the Alzheimer's Association.

8 Sep 2023

Compound Management and its Crucial Role in Early Pharmaceutical Research

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Silvio Di Castro about his research, as well as the role of compound management in pharmaceutical research.

From Society for Laboratory Automation and Screening (SLAS) 7 Sep 2023

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

To reimagine existing preclinical trials for Alzheimer's disease, University of Pittsburgh School of Medicine neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmoset monkeys, outlining their approach in Alzheimer's & Dementia: Translational Research & Clinical Interventions.

6 Sep 2023

Biosciences: how nature is changing the future of drug discovery

In this new podcast, Bruker's Kate Stumpo talks with Enveda's Pelle Simpson on the opportunities of natural products in the field of multiomics.

From Bruker Daltonics 6 Sep 2023

Clovibactin - a game-changing novel antibiotic with no resistance

Researchers reported the discovery of a new antibiotic, clovibactin.

6 Sep 2023

New cancer therapy shows promise in mouse models, slows or reverses tumor growth

A new cancer therapy developed by Purdue University researchers attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division.

4 Sep 2023

Silencing two genes can make cancer cells receptive to chemotherapy

Scientists from Queen Mary University of London have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it.

4 Sep 2023

Optibrium acquires BioPharmics LLC, expanding its 3D drug design and visualisation offering

Optibrium, a leading developer of software and AI solutions for drug discovery, today announced the acquisition of BioPharmics LLC.

From Optibrium Ltd. 31 Aug 2023

Higher educational attainment may have a protective effect against Alzheimer's in people with genetic risk

A new study by researchers from Mass General Brigham further illustrates that when it comes to risk of Alzheimer's disease, even genetically determined forms of the disease, genetics is only one piece of the puzzle.

30 Aug 2023

A move to cut drug prices has patients with rare diseases worried

For people with cystic fibrosis, like Sabrina Walker, Trikafta has been a life-changer.

30 Aug 2023

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Scale Biosciences, Inc. (ScaleBioTM), an innovator in single cell sequencing leveraging combinatorial indexing technologies, today announced an expansion of their product portfolio to enable a broader range of single cell omics experiments and unlock new translational research applications.

30 Aug 2023

CN Bio appoints Dr. Tomasz Kostrzewski as Chief Scientific Officer

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single-and multi-organ microphysiological systems (MPS), today announced the appointment of Dr. Tomasz Kostrzewski as Chief Scientific Officer.

From CN Bio 30 Aug 2023

Largest genetic study of heart failure finds new risk factors

In a new study co-led by investigators at the United States Department of Veterans Affairs and Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, a global team of scientists conducted one of the largest genetic association studies on heart failure to date.

24 Aug 2023

Griffith on the brink of technological breakthrough in vaccine development

Griffith University researchers are on the brink of a technological breakthrough in vaccine development with a possible new vaccine modality.

23 Aug 2023

Artificial intelligence and polyclonal antibody sequencing redefine the future of antibody discovery

In this interview, News-Medical had the opportunity to speak with Dr. Xiaobing Han, Principal Scientist for Antibody Discovery at Rapid Novor.

From Rapid Novor Inc 23 Aug 2023

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

The National Heart, Lung, and Blood Institute (NHLBI) recently awarded The Texas Heart Institute (THI) a two-year, $1.14 million grant to develop a novel, first-in-class drug to treat cardiovascular disease (CVD) as a significant improvement to current treatment regimens - specifically for adverse events arising from atherosclerosis.

22 Aug 2023

Genetically diverse mouse models offer new insights into Alzheimer's disease

A new study by Indiana University School of Medicine researchers uses more genetically diverse mouse models to study the accumulation and spread of abnormal tau protein deposits in the brain - a known sign of Alzheimer's disease and several other neurodegenerative diseases.

22 Aug 2023

The Alliance for Genomic Discovery announces founding biopharma members: AbbVie, Amgen, AstraZeneca, Bayer, and Merck

Illumina Inc., a global leader in DNA sequencing and array-based technologies, in collaboration with Nashville Biosciences, LLC, a leading clinical and genomic data company and wholly owned subsidiary of VUMC, today announced the five founding members of the Alliance for Genomic Discovery.

17 Aug 2023

Study sheds light on how cold temperatures affect appetite

Neuroscientists at Scripps Research have identified brain circuits that make mammals want to eat more when they are exposed to cold temperatures.

16 Aug 2023

Drug Discovery News and Research

Further Reading

Cerba Healthcare to acquire Canadian contract research laboratory Cirion Biopharma Research to expand bioanalytical capabilities and shorten time-to-deploy complex clinical trials

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Compound Management and its Crucial Role in Early Pharmaceutical Research

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

Biosciences: how nature is changing the future of drug discovery

Clovibactin - a game-changing novel antibiotic with no resistance

New cancer therapy shows promise in mouse models, slows or reverses tumor growth

Silencing two genes can make cancer cells receptive to chemotherapy

Optibrium acquires BioPharmics LLC, expanding its 3D drug design and visualisation offering

Higher educational attainment may have a protective effect against Alzheimer's in people with genetic risk

A move to cut drug prices has patients with rare diseases worried

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

CN Bio appoints Dr. Tomasz Kostrzewski as Chief Scientific Officer

Largest genetic study of heart failure finds new risk factors

Griffith on the brink of technological breakthrough in vaccine development

Artificial intelligence and polyclonal antibody sequencing redefine the future of antibody discovery

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

Genetically diverse mouse models offer new insights into Alzheimer's disease

The Alliance for Genomic Discovery announces founding biopharma members: AbbVie, Amgen, AstraZeneca, Bayer, and Merck

Study sheds light on how cold temperatures affect appetite

Pharmaron’s drug conjugates platform from idea to XDC eBook

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