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Scientists solve mystery surrounding mechanical forces that influence blood clotting

Researchers at the University of Sydney have used biomechanical engineering techniques to unlock the mystery surrounding the mechanical forces that influence blood clotting.

5 Apr 2019

FDA extends indication of metastatic breast cancer treatment to include male patients

The U.S. Food and Drug Administration today is extending the indication of Ibrance (palbociclib) capsules in combination with specific endocrine therapies for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in male patients.

5 Apr 2019

$Reformulated epileptic drug reaches first clinical trial for medically refractory epilepsy$

Reformulated epileptic drug reaches first clinical trial for medically refractory epilepsy

A currently approved epileptic drug to treat seizures has been modified by a University of Colorado Anschutz Medical Campus professor and is currently being used in a clinical trial in Australia for medically refractory epilepsy.

4 Apr 2019

DBS improves patients' cognitive control by increasing power of brain rhythms

In a new study that could improve the therapeutic efficacy of deep-brain stimulation for psychiatric disorders such as depression, a team of scientists shows that, when DBS is applied to a specific brain region, it improves patients' cognitive control over their behavior by increasing the power of a specific low-frequency brain rhythm in their prefrontal cortex.

4 Apr 2019

Patent-pending probiotic could help patients with gastrointestinal diseases avoid harmful biofilms

Probiotics typically aim to rebalance bacteria populations in the gut, but new research suggests they may also help break apart stubborn biofilms. Biofilms are living microbial communities--they provide a haven for microbes and are often resistant to antibiotics.

4 Apr 2019

New combination therapy found to be well tolerated in patients with aggressive brain tumor

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients.

30 Mar 2019

FDA approves new oral drug to treat relapsing forms of multiple sclerosis

The U.S. Food and Drug Administration today approved Mavenclad (cladribine) tablets to treat relapsing forms of multiple sclerosis (MS) in adults, to include relapsing-remitting disease and active secondary progressive disease.

29 Mar 2019

New targetable vulnerability in breast cancer cells discovered

Researchers at the University of Helsinki and Karolinska Institutet have discovered new molecular mechanisms of breast cancer cell signaling that contribute to aggressive behavior of cancer cells.

29 Mar 2019

Researchers discover how mosquitoes smell acidic volatiles in human sweat

Female mosquitoes are known to rely on an array of sensory information to find people to bite, picking up on carbon dioxide, body odor, heat, moisture, and visual cues.

29 Mar 2019

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Queen’s University Belfast and Domainex are pleased to announce that their joint project team has successfully identified novel first-in-class small molecule inhibitors of the anti-apoptotic protein FLIP.

29 Mar 2019

Study provides framework for developing Ebola virus therapeutic under FDA Animal Rule

The U.S. Army Medical Research Institute of Infectious Diseases today announced that, for the first time, the U.S. Food and Drug Administration has provided formal regulatory agreement for use of an animal model to support development of a drug candidate, remdesivir, for treating deadly Ebola virus infections.

29 Mar 2019

FDA approves treatment for adults with non-radiographic axial spondyloarthritis

The U.S. Food and Drug Administration today approved Cimzia (certolizumab pegol) injection for treatment of adults with a certain type of inflammatory arthritis called non-radiographic axial spondyloarthritis (nr-axSpA), with objective signs of inflammation. This is the first time that the FDA has approved a treatment for nr-axSpA.

28 Mar 2019

New strategy for potential treatment of HBV associated liver cancer

Researchers from Duke-NUS Medical School, Singapore General Hospital and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma, a commonly occurring liver cancer.

28 Mar 2019

First-of-its-kind smartphone app predicts dietary lapses

More than two-thirds of adults in the United States are overweight and half of them are trying to lose weight, according to the Centers for Disease Control and Prevention.

28 Mar 2019

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

A pioneering clinical trial investigating medicinal cannabis as a potential treatment for people living with severe Tourette syndrome will be conducted by Wesley Medical Research, in Brisbane in Australia, with cannabis supply facilitated by Lambert Initiative for Cannabinoid Therapeutics at University of Sydney.

28 Mar 2019

FDA approves new oral treatment for men with certain forms of hypogonadism

The U.S. Food and Drug Administration today approved Jatenzo (testosterone undecanoate), an oral testosterone capsule to treat men with certain forms of hypogonadism.

27 Mar 2019

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

Critical Path Institute announced today that a formal consultation between its Predictive Safety Testing Consortium and Japan's Pharmaceuticals and Medical Devices Agency has resulted in an agreement on a first-of-its-kind approach to compare the levels of eight novel urinary kidney safety biomarkers in healthy Japanese volunteers to data collected on these same biomarkers in healthy Western volunteers in a bridging study.

27 Mar 2019

Probing Submicron Protein Aggregation using Asymmetrical Flow Field-Flow Fractionation, AF4, and Light Scattering

The most recent developments by Wyatt in their instrumentation and software have made the full potential of FFF accessible to a wider user base. In this interview, Kim R. Williams and Christoph Johann talk to News-Medical and Life Sciences about the technologies and their research.

From Waters | Wyatt Technology 27 Mar 2019

AI technique identifies key patterns from video recording of infant movements

Subtle characteristics in the spontaneous movement of very young babies may reveal clinically important aspects of their neurodevelopment. Visual assessment of typical movement patterns (General movements, GM) by a clinical expert is known to be effective in early identification of e.g. cerebral palsy.

27 Mar 2019

Male contraceptive pill crosses the human clinical trial hurdle

Birth control pills have been around for the past six decades but have been for use of women only. A team of researchers this week have announced the success of the first male birth control pill that could safely prevent pregnancy.

27 Mar 2019

Efficacy News and Research

Scientists solve mystery surrounding mechanical forces that influence blood clotting

FDA extends indication of metastatic breast cancer treatment to include male patients

Reformulated epileptic drug reaches first clinical trial for medically refractory epilepsy

DBS improves patients' cognitive control by increasing power of brain rhythms

Patent-pending probiotic could help patients with gastrointestinal diseases avoid harmful biofilms

New combination therapy found to be well tolerated in patients with aggressive brain tumor

FDA approves new oral drug to treat relapsing forms of multiple sclerosis

New targetable vulnerability in breast cancer cells discovered

Researchers discover how mosquitoes smell acidic volatiles in human sweat

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Study provides framework for developing Ebola virus therapeutic under FDA Animal Rule

FDA approves treatment for adults with non-radiographic axial spondyloarthritis

New strategy for potential treatment of HBV associated liver cancer

First-of-its-kind smartphone app predicts dietary lapses

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

FDA approves new oral treatment for men with certain forms of hypogonadism

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

Probing Submicron Protein Aggregation using Asymmetrical Flow Field-Flow Fractionation, AF4, and Light Scattering

AI technique identifies key patterns from video recording of infant movements

Male contraceptive pill crosses the human clinical trial hurdle

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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