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Scientists explain how SARS-CoV-2 attacks the brain

Now, a team of scientists at Yale University revealed the changes that happen in the brain caused by SARS-CoV-2, the virus that has caused over 27.86 million people and claimed over 903,000 lives.

10 Sep 2020

Computer-designed proteins can protect lab-grown human cells from SARS-CoV-2

Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19.

10 Sep 2020

Pfizer, BioNTech COVID-19 vaccine candidate shows promise in preclinical study

Researchers in the United States and Germany have conducted a study demonstrating the preclinical efficacy of a new candidate vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

9 Sep 2020

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline associated with these disorders, suggests a pre-clinical study from researchers at Penn Medicine and Mayo Clinic.

8 Sep 2020

Study: Small neutralizing antibody can block SARS-CoV-2 from entering human cells

Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells.

4 Sep 2020

Spike ferritin nanoparticles show potential as SARS-CoV-2 vaccine

Now, a new study published on the preprint server bioRxiv* in August 2020 reports the induction of neutralizing antibodies in mice by a single dose of a ferritin nanoparticle-based vaccine containing the spike protein.

1 Sep 2020

Exploring the structure and dynamics of biological nanomachine

A small but important step towards a successful immune reaction is performed by an impressive nanomachine. Researchers use simulations to understand how it works.

28 Aug 2020

New method can help develop drugs that target membrane proteins

Portland State University researchers used advanced electron microscopy to create a 3-D reconstruction of a membrane protein at an unprecedented level of resolution, setting the stage for the development of drugs that could target the protein more effectively to treat a variety of diseases.

28 Aug 2020

Evidence of SARS-CoV-2 coronavirus particles in heart tissue

Researchers in Milan, Italy, have identified the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the heart tissue of deceased coronavirus disease 2019 (COVID-19) patients who had died from respiratory failure, without showing any signs of cardiac involvement.

27 Aug 2020

Using engineered off-the-shelf therapeutic T cells to fight cancer

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors.

20 Aug 2020

UT leads new project to explore the mysteries of brain connections

Researchers at The University of Texas at Austin will lead an ambitious new project with 10 other U.S. institutions and global partners that has significant implications for understanding human brain health.

19 Aug 2020

CUNY School of Medicine and TechnoVax announce COVID-19 vaccine breakthrough

The CUNY School of Medicine at The City College of New York and TechnoVax, Inc., a biotechnology developer of novel vaccines, announce a breakthrough in their collaborative effort to develop a vaccine for COVID-19.

19 Aug 2020

Structural analysis of SARS-CoV-2 can help develop COVID-19 vaccines

At the start of a COVID-19 infection, the coronavirus SARS-CoV-2 docks onto human cells using the spike-like proteins on its surface.

19 Aug 2020

Cryo-EM experiments offer important clues to chicken pox infection

Despite decades of study, exactly how herpesviruses invade our cells remains something of a mystery. Now researchers studying one herpesvirus, the varicella zoster virus (VZV) that causes chicken pox, may have found an important clue: A key protein the virus uses to initiate infection does not operate as previously thought, researchers at Stanford University and the Department of Energy's SLAC National Accelerator Laboratory report August 18 in Nature Communications.

18 Aug 2020

Cashew shell compound may help repair damaged nerves

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reports today in the Proceedings of the National Academy of Sciences.

17 Aug 2020

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

17 Aug 2020

Deciphering the largest CRISPR system

Professor Guillermo Montoya spoke to News-Medical on his research that involved visualizing the largest and most complex CRISPR system.

17 Aug 2020

Cyborg technology: Researchers take new step toward integrating electronics with the body

Although true "cyborgs" - part human, part robotic beings - are science fiction, researchers are taking steps toward integrating electronics with the body.

17 Aug 2020

SARS-CoV-2 spike pocket is a putative target for antiviral design

In a methodologically rigorous study, researchers from the University of Oxford have recently shown how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein harbors a lipid-binding pocket which modulates the stability of the prefusion trimer and provides conformational shielding from antibodies. Their findings are currently freely available on the bioRxiv* preprint server.

16 Aug 2020

Study shows how viruses operate and evade the immune system

University of Otago researchers have learnt more about how viruses operate and can evade the immune system and are now using their discovery to help learn more about COVID-19.

13 Aug 2020