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New advances offer hope for patients with systemic mastocytosis

Dana-Farber Cancer Institute researchers are breaking new ground in the fight against systemic mastocytosis, a rare and heterogeneous condition that is often challenging for clinicians to accurately diagnose and treat.

9 Dec 2024

Novel drug combination shows promise for CLL treatment

A novel, fixed-duration drug combination - consisting of a second-generation BTK inhibitor, called acalabrutinib, plus a BCL-2 inhibitor (venetoclax), with or without a third blood cancer drug - shows deep and durable responses in patients with chronic lymphocytic leukemia (CLL), Dana-Farber Cancer Institute investigator Jennifer Brown, MD, PhD, reports at the 66th American Society for Hematology (ASH) Annual Meeting and Exposition, on behalf of the trial investigators.

9 Dec 2024

CHOP study shows safety of rotavirus vaccine in neonatal intensive care unit

Researchers from Children's Hospital of Philadelphia (CHOP) found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, strongly suggesting that giving the rotavirus vaccine to eligible infants during their hospitalization provides immune benefits that outweigh any risks.

9 Dec 2024

Genetic factors increase prostate cancer risk for African men

Early testing is key to addressing the rise in cases of prostate cancer in Africa - and it doesn't have to be an invasive procedure.

6 Dec 2024

Air travel anxiety amplified for families dealing with food allergies

The skies aren't always so friendly for patients and families affected by food allergies, who may often experience worry and anxiety regarding airline travel, according to a new study from the Center for Food Allergy and Asthma Research at Northwestern University (CFAAR).

6 Dec 2024

A reduction in BMI among adults is associated with lower health care spending, study suggests

A study reveals that weight loss can lead to significant healthcare savings, with 7% savings for a 5% BMI reduction and 30% for a 25% reduction in adults.

6 Dec 2024

How measles, whooping cough, and worse could roar back on RFK Jr.’s watch

The availability of safe, effective covid vaccines less than a year into the pandemic marked a high point in the 300-year history of vaccination, seemingly heralding an age of protection against infectious diseases.

6 Dec 2024

Phase one trial explores novel immunotherapy for breast cancer

A groundbreaking phase one clinical trial exploring a novel cell-based immunotherapy for breast cancer has been accepted for publication in JAMA Oncology.

5 Dec 2024

Biomarker discovery offers hope for aggressive breast cancer treatment

A new study led by Lund University in Sweden has solved a years-old mystery: which patients with aggressive breast cancer are helped by a targeted cancer treatment that had been under development but was shelved.

4 Dec 2024

Women with premature ovarian insufficiency face higher risk of autoimmune diseases

Research reveals a significant association between premature ovarian insufficiency and autoimmune diseases, highlighting hypothyroidism as a common condition.

2 Dec 2024

Minority genetic variation in tuberculosis offers new insights for improving outbreak tracking

Findings show that within-host MTBC variation improves transmission inference, suggesting new strategies for understanding and controlling tuberculosis spread.

2 Dec 2024

Homebound seniors living alone often slip through health system’s cracks

Carolyn Dickens, 76, was sitting at her dining room table, struggling to catch her breath as her physician looked on with concern.

2 Dec 2024

Who gets obesity drugs covered by insurance? In North Carolina, it helps if you’re on Medicaid

After losing and regaining the same 20-plus pounds more times than she could count, Anita Blanchard concluded that diets don't work.

2 Dec 2024

New HIV prevention injection offers 96% protection

For oral medications that prevent new HIV infection to be effective, the patient must take certain actions, including attending doctor's visits every three months and – most importantly – consistency.

27 Nov 2024

Study links combined risk factors for aggressive behavior in men with CTE

People who have chronic traumatic encephalopathy (CTE) who have a family history of mental illness may have a higher risk of aggression in middle age, according to a study published in the November 27, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

27 Nov 2024

New injection treatment could be a game-changer for people with asthma and COPD

An injection given during some asthma and COPD attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30%.

27 Nov 2024

Childhood social disadvantage linked to increased MS severity

People who develop multiple sclerosis (MS) as children and grow up in less advantaged neighborhoods may have a larger volume of inflammation and brain tissue loss on imaging than those who grow up in more advantaged neighborhoods, according to a study published in the November 27, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

27 Nov 2024