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Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

Study finds higher heart attack risk days after cold exposure

Hospital admissions for heart attacks increase after exposure to lower air temperature and cold spells, according to a study published today in JACC, the flagship journal of the American College of Cardiology, and presented at the European Society of Cardiology (ESC) Congress 2024.

1 Sep 2024

Tau protein shows unexpected benefits in mitigating brain damage

A study by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, reveals that the protein Tau – a key player implicated in several neurodegenerative conditions including Alzheimer's disease – also plays a positive role in the brain.

30 Aug 2024

Rare genetic mutation tied to increased risk of tuberculosis

Tuberculosis is a confounding scourge. It's the leading cause of death from infectious disease in the world, and yet it's estimated that those deaths represent perhaps 5% of infections with Mycobacterium tuberculosis (Mtb).

30 Aug 2024

Benchmark Genetics Iceland remains unaffected by the ongoing volcanic eruption

Our facilities are situated outside the designated risk zone for the current seismic and volcanic activities near Grindavík, Iceland.

From Benchmark Genetics 30 Aug 2024

Fibrin fuels thromboinflammation and brain damage in COVID-19

Researchers reveal fibrin's critical role in COVID-19 by driving thromboinflammation and neuropathology, and highlight a potential antibody therapy to mitigate these effects.

29 Aug 2024

Studies uncover mechanisms behind micronuclear instability and cancer progression

Reactive oxygen species (ROS) from mitochondria are key drivers of genetic chaos in cancer by causing the collapse of micronuclear envelopes, a process that fuels the chromosomal instability (CIN) often observed in aggressive tumor behavior.

29 Aug 2024

NSF funds UCSB-led Biofoundry to revolutionize biotechnology with unexplored microbes

This week, the National Science Foundation announced the award of a six-year, $22M grant to UC Santa Barbara under its biofoundries program for the establishment of the BioFoundry for Extreme and Exceptional Fungi, Archaea and Bacteria (ExFAB), a collaboration led by UC Santa Barbara (UCSB), together with UC Riverside (UCR), and Cal Poly Pomona (CPP). ExFAB establishes the nation's first biofoundry that focuses on largely untapped and unexplored extreme microbes. UCSB's award is one of only five grants made under NSF's BioFoundry program during this funding cycle, which awarded a total of $75M to the five selected universities.

29 Aug 2024

16 promising postdoctoral scientists awarded Damon Runyon Fellowships for cancer research

The Damon Runyon Cancer Research Foundation has named 16 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

28 Aug 2024

New study develops enhanced mortality prediction model for COPD patients

Innovative probabilistic graph models identify unique factors linked to COPD mortality, paving the way for targeted interventions and improved patient outcomes.

28 Aug 2024

A study confirms that smoking significantly increases the risk of stroke

Findings indicate smoking elevates stroke risk, particularly in older males with comorbidities, underscoring the need for targeted prevention strategies.

28 Aug 2024

Benefits of less intensive stem cell transplants for sickle cell disease

So-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in some patients with sickle cell disease (SCD), according to a three-year study of adults who underwent the procedure at the National Institutes of Health (NIH).

28 Aug 2024

Scientists discover how a gut insulin antagonist controls fat loss in C. elegans by modulating brain signals

Researchers have identified an endogenous insulin antagonist, INS-7, in Caenorhabditis elegans that modulates fat loss by inhibiting a gut-to-brain signaling pathway involving the neuropeptide FLP-7.

27 Aug 2024

FDA-approved Alzheimer's drug induces torpor-like state in tadpoles

27 Aug 2024

The role of HPV in male fertility: New data on sperm quality and oxidative stress

Findings indicate HR-HPV infections affect sperm health, increasing oxidative stress and altering cytokine levels, emphasizing HPV's impact on male fertility.

27 Aug 2024

Mediterranean diet lowers COVID-19 risk, but its effect on symptoms and severity remains uncertain

Higher adherence to the Mediterranean diet is associated with a reduced risk of COVID-19, but its effects on symptom severity are less certain due to mixed results and study limitations.

27 Aug 2024

Study reveals metabolic switch crucial for memory T cell formation and cancer immunity

A Ludwig Cancer Research study has identified a metabolic switch in the immune system's T cells that is essential to the generation of memory T cells - which confer lasting immunity to previously encountered pathogens - and a T cell subtype found in tumors that drives anti-tumor responses during immunotherapy.

23 Aug 2024

FDA-approved drug could revolutionize organ transplantation

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University report that they were able to successfully put tadpoles of Xenopus laevis frogs into a hibernation-like torpor state using donepezil (DNP), a drug approved by the FDA to treat Alzheimer's. The team had previously used another drug, SNC80, to achieve similar results in tadpoles and enhance the survival of whole mammalian hearts for transplants, but SNC80 is not approved for clinical use in humans because it can cause seizures. By contrast, DNP is already being used in the clinic, meaning it potentially could be rapidly repurposed for use in emergency situations to prevent irreversible organ injury while a person is being transported to a hospital.

23 Aug 2024

Study confirms safety of high and low oxygen levels for cardiac surgery patients

Two out of 10 people who receive cardiac surgery are affected by acute kidney injury, prolonging their hospital stay and increasing their risk for chronic kidney disease, cognitive decline and heart failure.

21 Aug 2024

Metabolomics links increased heme iron intake to increased insulin-independent type 2 diabetes risk

Researchers utilie metabolomics to investigate the processes underlying dietary heme iron consumption and the risk of type 2 diabetes.

20 Aug 2024

Oxygen News and Research

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Study finds higher heart attack risk days after cold exposure

Tau protein shows unexpected benefits in mitigating brain damage

Rare genetic mutation tied to increased risk of tuberculosis

Benchmark Genetics Iceland remains unaffected by the ongoing volcanic eruption

Fibrin fuels thromboinflammation and brain damage in COVID-19

Studies uncover mechanisms behind micronuclear instability and cancer progression

NSF funds UCSB-led Biofoundry to revolutionize biotechnology with unexplored microbes

16 promising postdoctoral scientists awarded Damon Runyon Fellowships for cancer research

New study develops enhanced mortality prediction model for COPD patients

A study confirms that smoking significantly increases the risk of stroke

Benefits of less intensive stem cell transplants for sickle cell disease

Scientists discover how a gut insulin antagonist controls fat loss in C. elegans by modulating brain signals

FDA-approved Alzheimer's drug induces torpor-like state in tadpoles

The role of HPV in male fertility: New data on sperm quality and oxidative stress

Mediterranean diet lowers COVID-19 risk, but its effect on symptoms and severity remains uncertain

Study reveals metabolic switch crucial for memory T cell formation and cancer immunity

FDA-approved drug could revolutionize organ transplantation

Study confirms safety of high and low oxygen levels for cardiac surgery patients

Metabolomics links increased heme iron intake to increased insulin-independent type 2 diabetes risk

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