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Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

A new cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) shows that a drug that utilizes the body's immune system to target and eliminate cancer cells appeared to reduce the risk of distant metastases for an aggressive form of skin cancer when given immediately after surgery, but did not significantly reduce the overall risk of recurrence, which was a co-primary endpoint of the trial.

21 Oct 2025

Prima implant offers new hope for vision restoration in atrophic AMD

Age-related macular degeneration (AMD) causes progressive vision loss in many elderly people, and no treatment is available for the so-called atrophic form of the disease.

20 Oct 2025

Blood biomarkers forecast long-term blood pressure improvement after adolescent bariatric surgery

A groundbreaking study published in Hypertension, the journal of the American Heart Association, has identified a set of blood-based biomarkers that can predict improvements in blood pressure five years after adolescents underwent metabolic bariatric surgery.

20 Oct 2025

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

A multicenter Phase II clinical trial led by researchers at The University of Texas MD Anderson Cancer Center demonstrated significant tumor shrinkage and disease control in patients with advanced pheochromocytoma and paraganglioma (PPGL), two rare and potentially life-threatening neuroendocrine tumors.

18 Oct 2025

New antibody drug conjugates can transform early HER2-positive breast cancer treatment

In a landmark moment at the ESMO Congress 2025, pivotal studies have unveiled compelling evidence that a new class of anti-cancer agents-antibody-drug conjugates (ADCs)-can dramatically improve outcomes for patients with early-stage HER2-positive breast cancer.

18 Oct 2025

After chiding democrats on transgender politics, Newsom vetoes a key health measure

California Gov. Gavin Newsom this week signed a suite of privacy protection bills for transgender patients amid continuing threats by the Trump administration.

17 Oct 2025

Ingestible bioprinter offers minimally invasive tissue repair

Soft tissue injuries of the gastrointestinal tract, like ulcers or hemorrhages, can currently be treated only with some form of surgery, which is invasive and may not result in permanent repair.

16 Oct 2025

New framework aims to improve surgical quality improvement efforts

New study findings show the vast majority of small-scale quality improvement (QI) projects in surgery suffer from poor planning that can doom the effort from the start.

16 Oct 2025

Sleep-like brain waves persist in isolated cortex of epilepsy patients

Sleep-like slow-wave patterns persist for years in surgically disconnected neural tissue of awake epilepsy patients, according to a study published October 16th in the open-access journal PLOS Biology by Marcello Massimini from Universita degli Studi di Milano, Italy, and colleagues.

16 Oct 2025

NYU Langone sets the standard for organ transplant care

The NYU Langone Transplant Institute is the state's top-quality program for liver and kidney transplantation and has some of the fastest heart and lung transplant rates in the nation, according to the latest national data.

16 Oct 2025

World's largest-ever clinical trial launched to test treatments for Parkinson's disease

The world's largest-ever clinical trial of treatments to slow or stop the progression of Parkinson's disease has launched, led by researchers at UCL and Newcastle University.

16 Oct 2025

New AI system connects hidden clues in medical records to transform diagnosis

Doctors often must make critical decisions in minutes, relying on incomplete information. While electronic health records contain vast amounts of patient data, much of it remains difficult to interpret quickly-especially for patients with rare diseases or unusual symptoms.

15 Oct 2025

Predictive models identify high-risk liver cancer recurrence

Liver cancer is one of the world's deadliest malignancies, ranking as the third leading cause of cancer-related death.

14 Oct 2025

New composite sponge offers rapid and safe control of surgical hemorrhage

Uncontrolled bleeding during surgery remains one of the deadliest medical emergencies. Injuries to internal organs such as the liver or spleen are especially dangerous because bleeding is difficult to control and often life-threatening.

14 Oct 2025

WashU startup Prognosia acquired by Lunit to advance AI-based breast cancer prediction

An innovative biotech startup founded by researchers at Washington University School of Medicine in St. Louis has been acquired by Lunit, a leading company in developing AI-based technologies for cancer prevention and early detection.

14 Oct 2025

Breakthrough AI method redefines how doctors analyze medical images

When doctors analyze a medical scan of an organ or area in the body, each part of the image has to be assigned an anatomical label. If the brain is under scrutiny for instance, its different parts have to be labeled as such, pixel by pixel: cerebral cortex, brain stem, cerebellum, etc.

14 Oct 2025

Scientists revive diabetic beta cells, revealing a new path to restore insulin function

Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when cultured outside the diabetic environment. This recovery, driven by specific gene expression changes, identifies JAK inhibitors as potential therapeutic candidates to restore β-cell function.

14 Oct 2025

$Anesthesiologist-led care speeds surgery and reduces complications for hip fracture patients$

Anesthesiologist-led care speeds surgery and reduces complications for hip fracture patients

When anesthesiologists lead the preoperative process, patients undergoing surgery for hip fractures - one of the leading causes of hospitalization in older adults - get to the operating room (OR) faster and have fewer complications, according to a study presented at the ANESTHESIOLOGY® 2025 annual meeting.

13 Oct 2025

Daytime sleepiness in older adults linked to cognitive decline after surgery

People 60 and older who are excessively sleepy during the day may have more problems with memory and thinking after surgery, suggests a study presented at the ANESTHESIOLOGY 2025 annual meeting.

13 Oct 2025

How genomic screening in newborns found 16 hidden disorders standard tests overlooked

Genomic newborn screening using whole-genome sequencing identified 1.6% of infants with high-chance, treatable genetic conditions, far beyond the capacity of standard biochemical screening. The BabyScreen+ study demonstrated clinical impact, cascade diagnoses, and strong parental acceptance, while highlighting challenges in scalability and equity.

13 Oct 2025

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Surgery News and Research

Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

Prima implant offers new hope for vision restoration in atrophic AMD

Blood biomarkers forecast long-term blood pressure improvement after adolescent bariatric surgery

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

New antibody drug conjugates can transform early HER2-positive breast cancer treatment

After chiding democrats on transgender politics, Newsom vetoes a key health measure

Ingestible bioprinter offers minimally invasive tissue repair

New framework aims to improve surgical quality improvement efforts

Sleep-like brain waves persist in isolated cortex of epilepsy patients

NYU Langone sets the standard for organ transplant care

World's largest-ever clinical trial launched to test treatments for Parkinson's disease

New AI system connects hidden clues in medical records to transform diagnosis

Predictive models identify high-risk liver cancer recurrence

New composite sponge offers rapid and safe control of surgical hemorrhage

WashU startup Prognosia acquired by Lunit to advance AI-based breast cancer prediction

Breakthrough AI method redefines how doctors analyze medical images

Scientists revive diabetic beta cells, revealing a new path to restore insulin function

Anesthesiologist-led care speeds surgery and reduces complications for hip fracture patients

Daytime sleepiness in older adults linked to cognitive decline after surgery

How genomic screening in newborns found 16 hidden disorders standard tests overlooked

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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