Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Study offers insight into the basic cellular pathologies driving interstitial lung disease

While most people recover from COVID-19 within a week or two, up to one-third of survivors experience persistent or new symptoms weeks and months after initial infection.

21 Jul 2022

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure

research group led by Dr. Soichi Sano, a specially appointed lecturer in the Department of Cardiovascular Medicine, Graduate School of Medicine, Osaka Metropolitan University, revealed that men with hematopoietic mosaic loss of Y chromosome (mLOY) — meaning men with an increase, in the blood, of cells that have lost the male sex chromosome — have a worse prognosis for heart failure due to fibrosis progression in the heart.

15 Jul 2022

As Big Pharma loses interest in new antibiotics, infections are only growing stronger

Forget covid-19, monkeypox, and other viruses for the moment and consider another threat troubling infectious disease specialists: common urinary tract infections, or UTIs, that lead to emergency room visits and even hospitalizations because of the failure of oral antibiotics.

15 Jul 2022

Mosaic loss of Y chromosome increases risk for heart failure and cardiac fibrosis in men

Why a condition that frequently occurs in aging men, in which an increasing number of hematopoietic cells display a loss of the Y chromosome, is associated with increased risk of mortality and age-related diseases is now a little clearer, thanks to work in mice.

15 Jul 2022

Y chromosome loss in men can lead to deadly heart failure, research shows

The loss of the male sex chromosome as many men age causes the heart muscle to scar and can lead to deadly heart failure, new research from the University of Virginia School of Medicine shows.

14 Jul 2022

New liquid biopsy test found to be highly accurate, sensitive for both NASH and liver fibrosis

Researchers have created a liquid biopsy test, which uses two circulating proteins, to test for major liver diseases.

14 Jul 2022

BU researcher wins Cystic Fibrosis Foundation's Harry Shwachman Clinical Investigator Award

Andrew Berical, MD, Assistant Professor of Medicine at Boston University School of Medicine (BUSM), is the recipient of the Harry Shwachman Clinical Investigator Award from the Cystic Fibrosis Foundation (CFF).

12 Jul 2022

Experimental model reveals possible causes and treatments for long-COVID

In a recent study published in the journal Science Translational Medicine, researchers characterized long-term pulmonary consequences of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) mouse-adapted strain (MA10) infection in BALB/c laboratory mice.

11 Jul 2022

Researchers discover the first effective drug to treat rare, genetic liver disease

Researchers at Saint Louis University's School of Medicine, in collaboration with Arrowhead Pharmaceuticals and Takeda Pharmaceuticals, report the first effective drug to treat a rare, genetic liver disease that formerly could only be treated with a liver transplant.

8 Jul 2022

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

A recent study reported that long COVID in mice causes brain inflammation and cognitive impairment.

8 Jul 2022

The role of myostatin in female fertility

A new study discusses some of the key functions of myostatin in female reproductive health and disease.

6 Jul 2022

Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

The Damon Runyon Cancer Research Foundation has named five new Damon Runyon Clinical Investigators.

6 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

New method helps determine alcohol consumption in fatty liver disease

It is important to know whether patients have non-alcoholic fatty liver disease (NAFLD) or alcohol-related liver disease (ALD), as this distinction plays a key role in treatment and prognosis but cannot be reliably determined by established diagnostic means.

5 Jul 2022

SARS-CoV-2 infection of lung endothelial cells and pulmonary capillary microthrombosis

Researchers evaluated the presence of RNA of SARS-CoV-2 in lung tissue of deceased patients.

4 Jul 2022

Lower diaphragmatic thickness found among long COVID patients with unspecific fatigue and dyspnea

Researchers defined the sonographic diaphragm phenotype of long coronavirus disease (COVID) patients with unspecific fatigue and dyspnea.

4 Jul 2022

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

A team of clinician-scientists and scientists, led by the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore together with collaborators in Europe and South Korea, used single-cell techniques to uncover a central dichotomy for colorectal cancer cells, leading to a proposed update of the classification system for the disease.

1 Jul 2022

Study shows long COVID remodeling of T cell dynamics is dependent on SARS-CoV-2 severity

A new study found that the post-COVID-19 functional remodeling of T cells occurs in two steps and confers different convalescent immune states, six months after SARS-CoV-2 infection.

30 Jun 2022

New technique offers higher-precision scRNA-seq data than current technologies

The advent of single-cell RNA sequencing (scRNA-seq) has revolutionized the fields of medicine and biology by providing the ability to study the inner workings of thousands of cells at one go.

28 Jun 2022

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

Fibrosis News and Research

Further Reading

Study offers insight into the basic cellular pathologies driving interstitial lung disease

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure

As Big Pharma loses interest in new antibiotics, infections are only growing stronger

Mosaic loss of Y chromosome increases risk for heart failure and cardiac fibrosis in men

Y chromosome loss in men can lead to deadly heart failure, research shows

New liquid biopsy test found to be highly accurate, sensitive for both NASH and liver fibrosis

BU researcher wins Cystic Fibrosis Foundation's Harry Shwachman Clinical Investigator Award

Experimental model reveals possible causes and treatments for long-COVID

Researchers discover the first effective drug to treat rare, genetic liver disease

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

The role of myostatin in female fertility

Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

Novel inhalable COVID-19 vaccine

New method helps determine alcohol consumption in fatty liver disease

SARS-CoV-2 infection of lung endothelial cells and pulmonary capillary microthrombosis

Lower diaphragmatic thickness found among long COVID patients with unspecific fatigue and dyspnea

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

Study shows long COVID remodeling of T cell dynamics is dependent on SARS-CoV-2 severity

New technique offers higher-precision scRNA-seq data than current technologies

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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