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New method to induce embryonic stem cells to develop into bone marrow and blood cells

Researchers at Northwestern University have devised a method to induce embryonic stem cells to develop into bone marrow and blood cells. Injecting the stem cells into the bone marrow cavity of mice whose bone marrow cells had been depleted restored production of blood cells, including cells of the immune system, which normally are created in the bone marrow.

6 Apr 2004

Trauma Highly Prevalent Among Delinquents

Almost every boy and girl currently detained in a juvenile facility in the United States has experienced at least one major trauma, and a large proportion of these children have post-traumatic stress disorder, according to a study in the April issue of Archives of General Psychiatry.

6 Apr 2004

A new technique for engineering protein crystals is helping scientists figure out the three-dimensional structures of some important biological molecules

A new technique for engineering protein crystals is helping scientists figure out the three-dimensional structures of some important biological molecules, including a key plague protein whose structure has eluded researchers until now. The technique, developed with support from the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH), promises to help pharmaceutical companies develop more effective drugs to treat various diseases by tailor-making molecules to "fit" a protein's shape.

6 Apr 2004

Scientists studying vaccinia virus, a relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation

Scientists at the University of Illinois at Urbana-Champaign studying vaccinia virus, a close relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation, a crucial anti-viral immune response of host cells.

6 Apr 2004

Alzheimer's live about half as long as those of similar age without dementia

Age, seriousness of impairment, and the severity of other medical conditions are important indicators of how long an individual might survive after an Alzheimer's disease diagnosis, Eric B. Larson, M.D., M.P.H. and colleagues report in the April 6 Annals of Internal Medicine. Study authors include Linda Teri, Ph.D., recipient of an Alzheimer's Association $1 million Pioneer research grant.

6 Apr 2004

Genetic cause of cancer identified as a defect in the function of otherwise normal genes

In a landmark study published today in Nature Genetics, researchers from St Vincent's Hospital, The Victor Chang Cardiac Research Institute and the University of New South Wales have shown that a possible cause of cancer is a defect in the function of otherwise normal genes.

6 Apr 2004

Number of breaths given during CPR may be linked to survival

Researchers have identified a factor that may improve cardiac arrest survival rates according to a first-of-its-kind study of paramedic responses reported in today’s rapid access issue of Circulation: Journal of the American Heart Association.

5 Apr 2004

Collaboration to create a series of small molecule drugs leads against a Takeda target

Array BioPharma Inc. today announced the commencement of a drug discovery collaboration with Takeda Chemical Industries, Ltd. to create a series of small molecule drug leads against a Takeda target. This collaboration is in addition to Array's existing research agreement with Takeda that began in 2001.

5 Apr 2004

Ohio university to get major expansion cancer program

The Ohio State University Board of Trustees today has authorized the preparation of architectural and engineering plans for a possible major expansion of the university’s cancer program.

5 Apr 2004

Research shows giving Tourette Syndrome patients the drug levodopa normalizes brain activity

Scientists have known for years that abnormal activity involving a brain chemical called dopamine is somehow connected to the movements and vocalizations, or tics, associated with Tourette syndrome. Now neuroscience researchers at Washington University School of Medicine in St. Louis have found brain activity in these patients is abnormal during memory tasks, as well.

5 Apr 2004

A simple urine sample could soon be used to predict the complex toxic effects of new drugs

BlueGnome has pioneered the use of statistical signal modelling in the analysis of high throughput experimental data. Its first product BlueFuse for Microarrays uses statistical modelling techniques to eliminate Œnoise‚ generated in microarray experiments, enabling researchers to automatically identify the presence or absence of genes and proteins with a higher level of confidence than is currently possible.

5 Apr 2004

Implantable defibrillator cuts heart attack risk of sudden death by 31%

Researchers at Loyola University Health System, Maywood, Ill., and the University of Rochester Medical Center, Rochester, N.Y., found that the previously demonstrated survival benefit of ICDs following a heart attack can last up to 15 years.

5 Apr 2004

Common cholinesterase inhibitor eases behavioral symptoms like agitation, depression, and psychosis in patients

The so-called "memory drugs" used to treat Alzheimer's disease and other causes of dementia also ease or prevent a barrage of troublesome behaviors that affect the majority of patients, ultimately lightening the burden on caregivers, researchers have found. They report their results in the March issue of the American Journal of Psychiatry.

5 Apr 2004

Missed opportunities for addressing HIV testing remain unacceptably high

The researchers, led by Jeffrey Samet, MD, professor of medicine at BUSM and chief of General Internal Medicine at Boston Medical Center (BMC), performed a 10-year retrospective chart review of patients seen at an HIV intake clinic between January 1994 and June 2001 who: 1) tested positive for HIV during the 12 months prior to their presentation at the intake clinic and 2) had one or more encounters recorded in the medical record prior to their HIV positive status.

5 Apr 2004

Cordis Cardiology receives warning from the U.S. Food and Drug Administration

Cordis Cardiology, a division of Cordis Corporation, a Johnson & Johnson Company, reported today that it received a warning letter from the U.S. Food and Drug Administration (FDA) regarding FDA's observations concerning the Good Manufacturing Practice (GMP) regulations.

5 Apr 2004

Michigan opens new center to treat exposure to Vermiculite, Taconite, Asbestos

In response to the United States Environmental Protection Agency's (EPA) identification of major sources of public asbestos exposure in Michigan, the Barbara Ann Karmanos Cancer Institute and the Center for Occupational and Environmental Medicine (COEM) affiliated with Wayne State University (WSU) have joined forces to establish The National Center for Vermiculite and Asbestos-Related Cancers.

5 Apr 2004

New MRI Liver Contrast Agent Primovist(TM) Approved in Sweden

Schering AG Group, Germany has announced that the Swedish health authority MPA has granted marketing approval for its innovative liver imaging product Primovist(TM) (gadoxetic acid disodium). Primovist(TM) is designed for the detection and characterization of liver lesions by magnetic resonance imaging (MRI) including liver tumors, metastases as well as other malignant and benign lesions.

5 Apr 2004

Upcoming symposium to examine mercury exposure

The AMA is co-sponsoring a symposium for CME credit this month in Tampa, Fla., on the medical and public health aspects of mercury exposure. "Mercury: Medical and Public Health Issues" will be held from April 28-30 at the Tampa Marriott Waterside Hotel and Marina.

5 Apr 2004

First Approval in Europe of Ezetimibe/Simvastatin for treatment of elevated cholesterol

Merck/Schering-Plough Pharmaceuticals today announced the regulatory approval of INEGYTM (ezetimibe/simvastatin) in Germany for the treatment of elevated cholesterol (hypercholesterolemia). INEGY is the first product to reduce low-density lipoprotein cholesterol (LDL-C or ‘bad’ cholesterol), along with diet and exercise, through dual inhibition by inhibiting cholesterol production in the liver and absorption in the intestine. The approval of INEGY in Germany represents the first approval in Europe for ezetimibe/simvastatin tablets and the first step in seeking marketing approval throughout the European Union (EU) under the EU’s mutual recognition procedure.

4 Apr 2004

Doctors Likelier to Delay Prescribing Antiretroviral Drugs for Women and Minority HIV Patients

A new UCLA study finds that doctors who follow guidelines recommending the delay of antiretroviral therapy for non-adherent HIV patients are likelier to put off that treatment for Latinos, women and poor patients than they do for others. In addition, doctors are slower to prescribe protease inhibitors for African American patients whether or not the physician follows the guidelines.

4 Apr 2004

Medicine News and Research

New method to induce embryonic stem cells to develop into bone marrow and blood cells

Trauma Highly Prevalent Among Delinquents

A new technique for engineering protein crystals is helping scientists figure out the three-dimensional structures of some important biological molecules

Scientists studying vaccinia virus, a relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation

Alzheimer's live about half as long as those of similar age without dementia

Genetic cause of cancer identified as a defect in the function of otherwise normal genes

Number of breaths given during CPR may be linked to survival

Collaboration to create a series of small molecule drugs leads against a Takeda target

Ohio university to get major expansion cancer program

Research shows giving Tourette Syndrome patients the drug levodopa normalizes brain activity

A simple urine sample could soon be used to predict the complex toxic effects of new drugs

Implantable defibrillator cuts heart attack risk of sudden death by 31%

Common cholinesterase inhibitor eases behavioral symptoms like agitation, depression, and psychosis in patients

Missed opportunities for addressing HIV testing remain unacceptably high

Cordis Cardiology receives warning from the U.S. Food and Drug Administration

Michigan opens new center to treat exposure to Vermiculite, Taconite, Asbestos

New MRI Liver Contrast Agent Primovist(TM) Approved in Sweden

Upcoming symposium to examine mercury exposure

First Approval in Europe of Ezetimibe/Simvastatin for treatment of elevated cholesterol

Doctors Likelier to Delay Prescribing Antiretroviral Drugs for Women and Minority HIV Patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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