Efficacy News and Research

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Researchers publish new paper on developing vaccine candidates for Helminthic parasites

Helminthic parasites, like hookworm and liver flukes (schistosomiasis), affect an estimated 1 billion people worldwide. Infection from hookworm and schistosomiasis result in a combined loss of as much as 92 million disability-adjusted life years annually.

17 Aug 2018

New HIV therapy suppresses viral replication and increases immune cells in drug-resistant patients

In a study, a new HIV drug reduced viral replication and increased immune cells in individuals with advanced, drug-resistant HIV infection. Used in combination with existing HIV medications, the drug is a promising strategy for patients who have run out of effective treatment options, the researchers said.

16 Aug 2018

Study shows efficacy, safety of AAV5-based gene therapy to treat sheep model of achromatopsia

A study of a large animal model of achromatopsia caused by a mutation in the CNGA3 gene that was treated with a single injection of CNGA3 gene therapy delivered using an AAV5 vector revealed findings reported long-term follow-up findings that show promise for the efficacy and safety of this therapeutic approach.

15 Aug 2018

Researchers discover new promising target point for cancer and diabetes therapies

If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin and at the University of Geneva has a crucial influence on such signaling cascades and may be an important key for the future development of therapies against these diseases.

15 Aug 2018

Regular resistance training improves exercise motivation

A recent study conducted in the University of Jyväskylä suggests that resistance training improves exercise motivation and contributes to making exercise planning among older adults. Exercise motivation and exercise self-efficacy are key factors in continuing resistance training.

15 Aug 2018

NIH grant for Mount Sinai to study use of inhaled corticosteroids for treatment of sickle cell disease

The Departments of Emergency Medicine and Hematology at the Icahn School of Medicine at Mount Sinai have been awarded a $4 million grant from the National Institutes of Health toward further study of inhaled corticosteroids to treat sickle cell disease in individuals who do not have asthma.

14 Aug 2018

Using peripheral nerve blocks to treat facial pain may produce long-term pain relief

A new study has shown that use of peripheral nerve blocks in the treatment of Trigeminal Neuralgia may produce long-term pain relief.

14 Aug 2018

Experts provide insight into novel concepts and approaches for stroke rehabilitation

Stroke remains a leading cause of adult disability, and the global burden of stroke continues to grow with devastating consequences for patients, families, and caregivers.

14 Aug 2018

Study may help increase effectiveness of antibiotics against drug-resistant bacteria

Bacteria - especially Gram-negative strains - are becoming increasingly resistant to current antibiotic drugs, and the development of new classes of antibiotics has slowed.

13 Aug 2018

Incidence of coronary artery compression in children may be more common than previously thought

The incidence of coronary artery compression in children fitted with epicardial pacemakers may be slightly more common than previously believed, say noted cardiologists.

13 Aug 2018

Experts highlight key knowledge gaps that need to be addressed in Ebola vaccine research

Despite promising advances, important scientific questions remain unanswered in the effort to develop a safe and effective Ebola vaccine, according to members of an international Ebola research consortium.

13 Aug 2018

Genetically modified mosquitoes and special bed nets help tackle deadly diseases

Researchers at the Imperial College’s South Kensington campus have successfully created genetically modified mosquitoes that would stop them from multiplying and spreading dreaded diseases such as malaria, Dengue, Chikungunya and Zika that kill millions worldwide annually.

13 Aug 2018

FDA approves first oral medication for treatment of adults with Fabry disease

The U.S. Food and Drug Administration today approved Galafold (migalastat), the first oral medication for the treatment of adults with Fabry disease.

10 Aug 2018

FDA approves first vaginal ring contraceptive that can be used for one year

The U.S. Food and Drug Administration today approved Annovera (segesterone acetate and ethinyl estradiol vaginal system), which is a combined hormonal contraceptive for women of reproductive age used to prevent pregnancy and is the first vaginal ring contraceptive that can be used for an entire year.

10 Aug 2018

FDA approves first targeted RNA-based treatment for rare, fatal genetic disease

The U.S. Food and Drug Administration today approved Onpattro (patisiran) infusion for the treatment of peripheral nerve disease (polyneuropathy) caused by hereditary transthyretin-mediated amyloidosis (hATTR) in adult patients.

10 Aug 2018

$Initiation of PIMs associated with higher risk of fracture-specific hospitalizations and mortality$

Initiation of PIMs associated with higher risk of fracture-specific hospitalizations and mortality

A recent study published in The European Journal of Health Economics finds that the initiation of potentially inappropriate medication is associated with a higher risk of fracture-specific hospitalizations and mortality.

10 Aug 2018

New discovery could pave way for improved leukemia treatment

Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess this favorable mutation, but until now, how it helps improve outcomes has remained unknown.

9 Aug 2018

Cleveland Clinic awarded $4.7 million grant to study prevention of cancer-associated blood clots

The National Heart, Lung and Blood Institute (NHLBI), part of the National Institutes of Health, awarded a $4.7 million grant to Cleveland Clinic to study the prevention of life-threatening, cancer-associated blood clots.

9 Aug 2018

New drug delivery system delivers anticancer drugs that reduce tumor size

Cancer tissue cells are divided into two major groups: cancer cells and cancer stem cells. CSCs are related to cancer progression and dissemination, so it's necessary to eradicate CSCs in order to cure cancer.

9 Aug 2018

New review examines potential of medicinal cannabis to help treat intractable epilepsy

A new British Journal of Clinical Pharmacology review examines the potential of medicinal cannabis--or medical marijuana--for helping patients with intractable epilepsy, in which seizures fail to come under control with standard anticonvulsant treatment.

8 Aug 2018

Efficacy News and Research

Researchers publish new paper on developing vaccine candidates for Helminthic parasites

New HIV therapy suppresses viral replication and increases immune cells in drug-resistant patients

Study shows efficacy, safety of AAV5-based gene therapy to treat sheep model of achromatopsia

Researchers discover new promising target point for cancer and diabetes therapies

Regular resistance training improves exercise motivation

NIH grant for Mount Sinai to study use of inhaled corticosteroids for treatment of sickle cell disease

Using peripheral nerve blocks to treat facial pain may produce long-term pain relief

Experts provide insight into novel concepts and approaches for stroke rehabilitation

Study may help increase effectiveness of antibiotics against drug-resistant bacteria

Incidence of coronary artery compression in children may be more common than previously thought

Experts highlight key knowledge gaps that need to be addressed in Ebola vaccine research

Genetically modified mosquitoes and special bed nets help tackle deadly diseases

FDA approves first oral medication for treatment of adults with Fabry disease

FDA approves first vaginal ring contraceptive that can be used for one year

FDA approves first targeted RNA-based treatment for rare, fatal genetic disease

Initiation of PIMs associated with higher risk of fracture-specific hospitalizations and mortality

New discovery could pave way for improved leukemia treatment

Cleveland Clinic awarded $4.7 million grant to study prevention of cancer-associated blood clots

New drug delivery system delivers anticancer drugs that reduce tumor size

New review examines potential of medicinal cannabis to help treat intractable epilepsy

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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