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Study provides new insights into development of Sonic Hedgehog medulloblastoma

Medulloblastoma is the most common type of solid brain tumor in children. Current treatments offer limited success and may leave patients with severe neurological side effects, including psychiatric disorders, growth retardation and cognitive impairment.

13 Dec 2017

Researchers adopt new approach to treating advanced prostate cancer

Scientists have proposed a new approach to preventing the proliferation of prostate tumor cells that are no longer responding to treatment. Prostate cancer can usually be cured via surgical removal of the tumor and/or the use of radiotherapy, but in one-fifth of cases, patients also require treatment with drugs to continue removing tumor cells. However, these drugs are only effective for up to three years, after which the cancer continues to develop.

13 Dec 2017

Researchers discover new way to attack drug-resistant prostate cancer cells

In most cases, prostate cancer is cured by surgical removal of the tumor and/or by radiotherapy. However, 20% of patients will need treatment to remove tumor cells but this treatment ceases to be effective after two or three years and the cancer develops further.

13 Dec 2017

Blood test using infrared spectroscopy can help detect two cancer types

A blood test using infrared spectroscopy can be used to diagnose two types of cancer, lymphoma and melanoma, according to a study led by Georgia State University.

12 Dec 2017

Scientists develop new method for more effective photothermal treatment of tumors

Nanorods made of bismuth sulfide kill tumor cells with heat when they are irradiated with near-infrared light. Chinese scientists are now making these weapons more powerful by remodeling the defect state of the nanorod crystal lattice by adding gold nanodots.

12 Dec 2017

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced new results from two studies with EndoPredict are being featured at the 2017 San Antonio Breast Cancer Symposium in San Antonio, Texas.

12 Dec 2017

Hidden genes hold blueprints for designing new anti-cancer drugs

New research suggests these hidden genes hold the blueprints for designing new, even more effective cancer-targeting compounds.

12 Dec 2017

Researchers find new role for SHARPIN protein in melanoma growth

Researchers at Sanford Burnham Prebys Medical Discovery and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex, regulating NFκB and other inflammatory molecules, SHARPIN modulates PRMT5, an epigenetic master switch that controls several proteins linked to melanoma. The research was published in The Journal of Clinical Investigation.

12 Dec 2017

Study: Combination targeted therapy has high response rates in AML patients

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2017

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Researchers uncover novel strategy to program immune system for fighting cancer

Looking to bolster the body's immune system in the fight against infection and cancer, researchers at the University of California San Diego and their colleagues have identified a promising new strategy to program the immune system to meet the pathogen or malignancy in the tissues where they first pose a threat.

11 Dec 2017

Study provides new insights into mechanism of tumor survival in glioblastoma

A Northwestern Medicine study, published in the journal Cancer Cell, has provided new insights into a mechanism of tumor survival in glioblastoma and demonstrated that inhibiting the process could enhance the effects of radiation therapy.

11 Dec 2017

Researchers discover potential regulator essential for killer T cells to reside in tumors

Researchers report the discovery that a protein called "Runx3" programs killer T cells to establish residence in tumors and infection sites.

11 Dec 2017

Tgen And Baylor secure federal grant to develop early detection system for pancreatic cancer

A group of the nation's premier cancer researchers led by the Baylor Scott & White Research Institute and the Translational Genomics Research Institute -- has secured a $5.13 million federal grant to develop an early detection system for pancreatic cancer, the nation's third-leading cause of cancer-related death.

11 Dec 2017

Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer

An international research team headed by the University of Bern and the Netherlands Cancer Institute has developed 3D cell cultures in which genes can be specifically modified. They allow the study of genes that may cause therapy resistance in breast cancer.

11 Dec 2017

New, more easily administered therapies offer benefits for bleeding and clotting disorders

In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits from new, more easily administered therapies for bleeding and clotting disorders.

11 Dec 2017

Scientists develop software that predicts leukemia-specific immune targets

University of North Carolina Lineberger Comprehensive Cancer Center scientists have developed a software program that can accurately predict which tumor-specific markers will show up on the surface of leukemia cells in patients who have received stem cell transplants.

11 Dec 2017

Study indicates decline in use of chemotherapy for early stage breast cancer patients

A study of nearly 3,000 women with early stage breast cancer indicates a recent, significant decline in the use of chemotherapy despite the lack of any change in national treatment recommendations or guidelines, according to researchers at the Stanford University School of Medicine and the University of Michigan.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Bi-annual MRI beats mammograms in detecting breast cancer among women with genetic risk

Intensive surveillance including a dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) exam every six months was far more effective in detecting breast cancer in younger women with a high-risk genetic profile than an annual mammogram, according to a research team based at the University of Chicago Medicine and the University of Washington, Seattle.

11 Dec 2017

Tumor News and Research

Study provides new insights into development of Sonic Hedgehog medulloblastoma

Researchers adopt new approach to treating advanced prostate cancer

Researchers discover new way to attack drug-resistant prostate cancer cells

Blood test using infrared spectroscopy can help detect two cancer types

Scientists develop new method for more effective photothermal treatment of tumors

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Hidden genes hold blueprints for designing new anti-cancer drugs

Researchers find new role for SHARPIN protein in melanoma growth

Study: Combination targeted therapy has high response rates in AML patients

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Researchers uncover novel strategy to program immune system for fighting cancer

Study provides new insights into mechanism of tumor survival in glioblastoma

Researchers discover potential regulator essential for killer T cells to reside in tumors

Tgen And Baylor secure federal grant to develop early detection system for pancreatic cancer

Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer

New, more easily administered therapies offer benefits for bleeding and clotting disorders

Scientists develop software that predicts leukemia-specific immune targets

Study indicates decline in use of chemotherapy for early stage breast cancer patients

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Bi-annual MRI beats mammograms in detecting breast cancer among women with genetic risk

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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