Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Novel 3D maps show how genes interact in several types of immune cells

The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.

22 Dec 2020

£6.7m awarded to find new ways to improve prevention, diagnosis and treatment of diseases

Barts Life Sciences - a partnership between Barts Health NHS Trust and Queen Mary University of London - has been awarded £6.7m by Barts Charity to research new ways to improve the prevention, diagnosis and treatment of a variety of diseases.

18 Dec 2020

Researchers investigate microbiome-mediated therapies for aging and health span

Texas Biomedical Research Institute Associate Professor Corinna Ross, PhD, is a principal investigator on a $3.38 million National Institutes of Health multi-investigator grant to study "microbiome-mediated therapies for aging and healthspan" in marmosets, which are small monkeys native to South America and are becoming increasingly more important in aging and infectious disease research.

18 Dec 2020

Researchers discover cells responsible for resistance to T-ALL treatment

T-cell acute lymphoblastic leukemia (T-ALL) is a cancer of the blood that affects mainly children, but also less frequently adults. In adults, although the response to treatment might be initially positive, relapses are common and have a poor prognosis.

17 Dec 2020

Researchers identify key gene necessary for cells to consume and destroy viruses

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve the immune system's ability to combat viral infections, such as those fueling the ongoing COVID-19 pandemic.

17 Dec 2020

A new approach to identify genomic regions in our brain that contribute to make us human

With only 1% difference, the human and chimpanzee protein-coding genomes are remarkably similar.

16 Dec 2020

Scientists identify new Salmonella proteins

Salmonella are bacteria that can cause food poisoning with severe diarrhea. If they penetrate from the intestine into the blood system, this can lead to sepsis, life-threatening inflammatory reactions in the entire organism.

16 Dec 2020

SARS-CoV-2 unique deletion variants found in clinical specimens

While participating in the SPHERES Consortium project, US researchers sequenced 2,726 clinical patient specimens gathered in March 2020 and identified eight unique ORF7a deletion variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their results are currently available on the bioRxiv* preprint server.

15 Dec 2020

Prior T cell immunity to SARS-CoV-2 unlikely to be the result of seasonal coronavirus infection

Scientists have suggested that a proportion of the population have pre-existing immunity to COVID-19 because of T cells primed against SARS-CoV-2 antigens.

14 Dec 2020

Study unlocks some muscle cell secrets

A muscle fiber consists of just one cell, but many nuclei. A team at the MDC led by Professor Carmen Birchmeier has now shown just how varied these nuclei are.

11 Dec 2020

Research provides new insights into Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

11 Dec 2020

Study findings can guide personalized breast cancer therapies based on melatonin

A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin in some types of cancer, especially breast cancer.

8 Dec 2020

Researchers develop new approach for COVID-19 testing

Researchers from UC San Francisco and the Chan Zuckerberg Biohub have developed a new approach for COVID-19 testing that detects a distinct pattern of immune gene expression in infected individuals.

7 Dec 2020

Study reveals genetic abnormalities that cause brain aneurysms

Nearly three percent of the world's population is at risk of developing an intracranial aneurysm, a localized dilation of a blood vessel forming a fragile pocket. Rupture of this aneurysm results in extremely severe, and, in one-third of cases, fatal hemorrhage.

7 Dec 2020

Researchers identify new target that may lead to novel treatment for Alzheimer’s disease

Researchers at the Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer's disease (AD) that could lead to therapies focused on treating the neurodegenerative condition early in its progression.

7 Dec 2020

Scientists develop new bioinformatics pipeline to identify viruses in environmental samples

Researchers from the University of Helsinki have developed a novel bioinformatics pipeline called Lazy pipe for identifying viruses in host-associated or environmental samples.

3 Dec 2020

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

SARS-CoV-2's microRNAs may have promoted its jump to humans

A new study uses machine learning to explore the small microRNAs (or miRNAs) of SARS-CoV-2 that may determine the virus's ability to successfully infect humans by altering the course of transcriptional events.

1 Dec 2020

Researchers report AI solution that could revolutionize medical research

Inside every cell, thousands of different proteins from the machinery that keeps all living things - from humans and plants to microscopic bacteria - alive and well. Almost all diseases, including cancer, dementia, and even infectious diseases such as COVID-19, are related to the way these proteins function.

1 Dec 2020

Machine learning model uses retinal scans to detect Alzheimer’s disease

A form of artificial intelligence designed to interpret a combination of retinal images was able to successfully identify a group of patients who were known to have Alzheimer's disease, suggesting the approach could one day be used as a predictive tool, according to an interdisciplinary study from Duke University.

30 Nov 2020