Wound Healing News and Research

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New treatment options for diabetic wound healing in cornea and skin

Diabetes Mellitus (DM), a metabolic disorder that affects nearly 170 million people worldwide, is characterized by chronic hyperglycemia that disrupts carbohydrate fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. DM can cause long-term damage, dysfunction and even failure of various organs.

13 Dec 2013

Equations help explain key parameters of stents that combat artherosclerosis

Coronary heart disease accounts for 18% of deaths in the United States every year. The disease results from a blockage of one or more arteries that supply blood to the heart muscle.

9 Dec 2013

Adocia gets development and commercialization rights in nanotechnology for drug delivery

Adocia, a biotechnology company specializing in the development of ‘best-in-class’ medicines from already approved therapeutic proteins, announces today the signature of an exclusive license agreement with the CNRS, the University Bordeaux I, the Institut Polytechnique de Bordeaux and Aquitaine Science Transfert.

9 Dec 2013

‘Flesh-eating’ disease treatments: an interview with Dr. John Crew, Seton Medical Center

Untreated, the mortality probably exceeds 70%. Flesh eating is a description of Toxic Inflammatory Cellulitis which usually starts by bacterial subcutaneous infection followed by freezing in phase II healing which is inflammatory.

9 Dec 2013

Current laser therapy approaches provide effective treatment for excessive scars

Current laser therapy approaches are effective for treating excessive scars resulting from abnormal wound healing, concludes a special topic paper in the December issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

27 Nov 2013

EPCs: A promising therapy for type 1 diabetes

Pancreatic islet transplantation is a promising therapy for treating type 1 diabetes, but the majority of transplanted cells die soon after they are transplanted.

27 Nov 2013

Carl-Philipp Heisenberg group detects mechanism in cell division relevant for closing wounds

Spreading of the epithelial cell layer is fundamental for epithelial closure and wound healing, as well as for embryonic development. The challenge presented here is that the cell layer needs to increase in surface area, but nevertheless maintain its integrity.

16 Nov 2013

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

Skin provides a first line of defense against viruses, bacteria and parasites that might otherwise make people ill. When an injury breaks that barrier, a systematic chain of molecular signaling launches to close the wound and re-establish the skin's layer of protection.

16 Nov 2013

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

A team of scientists that includes Saint Louis University researchers has identified a new way to intervene in the molecular and cellular cascade that causes fibrosis - a condition where the body's natural process of forming scars for wound healing goes into overdrive and causes diseases.

11 Nov 2013

Researchers able to regrow bone, hair, soft tissues and cartilage in mouse model

Young animals are known to repair their tissues effortlessly, but can this capacity be recaptured in adults? A new study from researchers at the Stem Cell Program at Boston Children's Hospital suggests that it can. By reactivating a dormant gene called Lin28a, which is active in embryonic stem cells, researchers were able to regrow hair and repair cartilage, bone, skin and other soft tissues in a mouse model.

8 Nov 2013

Orthopaedic foot and ankle MDs offer tips for diabetic foot care

It's American Diabetes Month, and if you're among the 25 million Americans who have diabetes, you may know that foot care is extremely important. Nervous system impairment, also called neuropathy, is a major complication of diabetes that can cause you to lose feeling in your feet. This means you may not know right away if you have hurt yourself, which could lead to infection.

4 Nov 2013

ARIAD temporarily suspends commercial distribution of Iclusig drug in US

ARIAD Pharmaceuticals, Inc. today announced that it is temporarily suspending the marketing and commercial distribution of Iclusig® (ponatinib), a treatment for patients with resistant or intolerant chronic myeloid leukemia (CML) and Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph+ ALL), in the United States, while it continues to negotiate updates to the U.S. prescribing information for Iclusig and implementation of a risk mitigation strategy.

31 Oct 2013

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Making fat cells immortal might seem like a bad idea to most people, but for a team of University of Iowa scientists it was the ideal way to study how the interaction between bacteria and fat cells might contribute to diabetes.

31 Oct 2013

Research findings open up possibility for developing potent anti-clotting drugs

Researchers at the University of Illinois at Chicago have discovered a molecular switch that causes small, beneficial clots that stop bleeding to enlarge further during wound healing. By blocking this switch in lab mice, the researchers prevented small clots from growing -- a process that can pose a danger in humans -- while preserving their ability to staunch bleeding

29 Oct 2013

APR's Nexodyn receives European CE approval

APR announces the grant of the European CE approval of Nexodyn, a newly developed innovative product intended for use in a variety of wound conditions such as acute wounds, burns and advanced ulcers including venous and pressure ulcers and diabetic foot ulcers.

28 Oct 2013

Rice University research reveals 3-way genetic switch for cancer metastasis

Cancer researchers from Rice University have deciphered the operating principles of a genetic switch that cancer cells use to decide when to metastasize and invade other parts of the body. The study found that the on-off switch's dynamics also allows a third choice that lies somewhere between "on" and "off." The extra setting both explains previously confusing experimental results and opens the door to new avenues of cancer treatment.

25 Oct 2013

Breast milk may protect babies from acquiring HIV infection, say researchers

A substance in breast milk that neutralizes HIV and may protect babies from acquiring HIV from their infected mothers has been identified for the first time by researchers at Duke Medicine.

22 Oct 2013

Clarified role of signal-relay proteins may help explain spread of cancer

Cell biologists at The Johns Hopkins University have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.

21 Oct 2013

Valley Presbyterian Hospital doc awarded 2013 Achievement Award in Diabetic Limb Salvage

George Andros, MD, Founder and Medical Director of the Amputation Prevention Center at Valley Presbyterian Hospital, was honored with the MedStar Georgetown 2013 Distinguished Achievement Award in Diabetic Limb Salvage.

19 Oct 2013

ARIAD discontinues Phase 3 EPIC trial of Iclusig in patients with chronic myeloid leukemia

ARIAD Pharmaceuticals, Inc. today announced that it is discontinuing the Phase 3 EPIC (Evaluation of Ponatinib versus Imatinib in Chronic Myeloid Leukemia) trial of Iclusig (ponatinib) in patients with newly diagnosed chronic myeloid leukemia.

18 Oct 2013

Wound Healing News and Research

New treatment options for diabetic wound healing in cornea and skin

Equations help explain key parameters of stents that combat artherosclerosis

Adocia gets development and commercialization rights in nanotechnology for drug delivery

‘Flesh-eating’ disease treatments: an interview with Dr. John Crew, Seton Medical Center

Current laser therapy approaches provide effective treatment for excessive scars

EPCs: A promising therapy for type 1 diabetes

Carl-Philipp Heisenberg group detects mechanism in cell division relevant for closing wounds

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

Researchers able to regrow bone, hair, soft tissues and cartilage in mouse model

Orthopaedic foot and ankle MDs offer tips for diabetic foot care

ARIAD temporarily suspends commercial distribution of Iclusig drug in US

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Research findings open up possibility for developing potent anti-clotting drugs

APR's Nexodyn receives European CE approval

Rice University research reveals 3-way genetic switch for cancer metastasis

Breast milk may protect babies from acquiring HIV infection, say researchers

Clarified role of signal-relay proteins may help explain spread of cancer

Valley Presbyterian Hospital doc awarded 2013 Achievement Award in Diabetic Limb Salvage

ARIAD discontinues Phase 3 EPIC trial of Iclusig in patients with chronic myeloid leukemia

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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