Efficacy News and Research

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Hematopoietic stem cell transplant improves survival for multiple myeloma patients

Researchers at UC Davis have confirmed that autologous hematopoietic stem cell transplant improves survival for people suffering from multiple myeloma, yet many potentially eligible patients never undergo the procedure.

13 Jun 2018

Researchers develop spider silk microcapsules that can deliver vaccine directly to immune cells

To fight cancer, researchers increasingly use vaccines that stimulate the immune system to identify and destroy tumor cells.

12 Jun 2018

Carboxytherapy eliminates belly fat

The first randomized, controlled trial testing carbon dioxide gas injections (carboxytherapy) to reduce belly fat found the new technique eliminates fat around the stomach. However, the changes were modest and did not result in long-term fat reduction, according to the Northwestern Medicine study.

8 Jun 2018

International experts agree on need for human-relevant research to improve drug discovery

The average pre-approval cost of research and development for a successful drug is estimated to be US$2.6 billion and the number of new drugs approved per billion US dollars spent has halved roughly every 9 years since 1950.

8 Jun 2018

Researchers uncover why people with Parkinson's disease suffer from sleep disturbances

A team of researchers at VIB and KU Leuven has uncovered why people with a hereditary form of Parkinson's disease suffer from sleep disturbances.

8 Jun 2018

Researchers discover new therapy combination that may help treat ovarian cancer

Researchers at The University of Kansas Cancer Center have discovered a therapy combination that may be helpful in the treatment of certain types of ovarian cancer.

8 Jun 2018

Research project aims to study opioid prescriptions after cesarean delivery and hysterectomy

Each year, approximately 1.8 million women will have a cesarean delivery or hysterectomy. While opioids are the mainstay treatment for acute pain after these surgeries, most women use only a fraction of the opioids prescribed and do not properly dispose of unused drugs

7 Jun 2018

Researchers develop model that predicts changes in BUP exposure during pregnancy

Buprenorphine (BUP) is approved for the treatment of opioid addiction. The current dosing regimen of BUP in pregnant women is based on recommendations designed for non-pregnant adults, but physiological changes during pregnancy may alter BUP exposure and efficacy.

7 Jun 2018

AFA awards grant to Stony Brook Medicine to improve drug development for Alzheimer's disease

The Alzheimer's Foundation of America is awarding $206,184 over the next three years to Stony Brook Medicine to support an innovative Positron Emission Tomography imaging research project that will compare neurons from healthy controls and those with Alzheimer's disease in an effort to improve drug development.

7 Jun 2018

Web-based salt education program helps reduce salt intake among children

Consuming excessive salt during childhood is associated with cardiovascular health risk factors, yet the effectiveness of education- and behavior-based strategies to lower salt usage among children has not been fully researched.

7 Jun 2018

Two-drug combination provides more reliable, effective care for women suffering miscarriage

A combination of the drugs mifepristone and misoprostol can help bring closure to some women and their families suffering from miscarriage, and reduces the need for surgical intervention to complete the painful miscarriage process.

7 Jun 2018

Researchers’ attempt to combine immunotherapy drugs have turned out to be failure

A class of immunotherapy drugs called checkpoint inhibitors has shown great promise against cancer in some patients.

7 Jun 2018

Regeneron collaborates with Zoetis to research antibody therapies for animals

Regeneron Pharmaceuticals, Inc. and Zoetis Inc. today announced a five-year collaboration to research the use of Regeneron's monoclonal antibody therapeutics in animals and discover new veterinary treatments.

6 Jun 2018

Researchers develop new scoring criteria to evaluate quality of scientific research proposals

Researchers at Boston University's Evans Center for Implementation and Improvement Sciences (CIIS) have developed a new scoring criteria for evaluating the quality of scientific research proposals.

5 Jun 2018

Novel PET imaging shows promise for noninvasively detecting inflammation in people with IBD

A novel positron emission tomography imaging method shows promise for noninvasively pinpointing sites of inflammation in people with inflammatory bowel disease, which includes ulcerative colitis and Crohn's disease.

4 Jun 2018

Researchers report on the sweet side of snake venom toxins

A bite from a lancehead snake can be fatal. Species in the family, found throughout Central and South America, have venom that can disrupt blood clotting and cause hemorrhage, strokes and kidney failure.

4 Jun 2018

Protein inhibitor drug found to be safe and effective in treating patients with acute myeloid leukemia

Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers has been shown to be safe, resulting in durable remissions, in a study of acute myeloid leukemia with relapsed or refractory disease.

4 Jun 2018

Diuretic drug may be just as effective as oral antibiotics to treat acne in female patients

In a finding that suggests the potential for practice change that would reduce the use of antibiotics in dermatology, researchers in the Perelman School of Medicine at the University of Pennsylvania have found the diuretic drug spironolactone may be just as effective as antibiotics for the treatment of women's acne.

4 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Research project offers hope for pediatric patients with thalassemia

Children born with thalassaemia, a genetic blood disease, cannot create normal haemoglobin, which is needed to produce healthy red blood cells. Regular blood transfusions are the only treatment available, but iron overload is inevitable.

1 Jun 2018

Efficacy News and Research

Hematopoietic stem cell transplant improves survival for multiple myeloma patients

Researchers develop spider silk microcapsules that can deliver vaccine directly to immune cells

Carboxytherapy eliminates belly fat

International experts agree on need for human-relevant research to improve drug discovery

Researchers uncover why people with Parkinson's disease suffer from sleep disturbances

Researchers discover new therapy combination that may help treat ovarian cancer

Research project aims to study opioid prescriptions after cesarean delivery and hysterectomy

Researchers develop model that predicts changes in BUP exposure during pregnancy

AFA awards grant to Stony Brook Medicine to improve drug development for Alzheimer's disease

Web-based salt education program helps reduce salt intake among children

Two-drug combination provides more reliable, effective care for women suffering miscarriage

Researchers’ attempt to combine immunotherapy drugs have turned out to be failure

Regeneron collaborates with Zoetis to research antibody therapies for animals

Researchers develop new scoring criteria to evaluate quality of scientific research proposals

Novel PET imaging shows promise for noninvasively detecting inflammation in people with IBD

Researchers report on the sweet side of snake venom toxins

Protein inhibitor drug found to be safe and effective in treating patients with acute myeloid leukemia

Diuretic drug may be just as effective as oral antibiotics to treat acne in female patients

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Research project offers hope for pediatric patients with thalassemia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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