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New system for anti-cancer drug delivery offers hope to treat pediatric tumors

In most of the Western World, cancer is the primary cause of death in children over the age of one. Existing treatments for adult cancer patients are not particularly effective for children.

31 May 2018

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

The U.S. Food and Drug Administration today expanded the approval of Xeljanz (tofacitinib) to include adults with moderately to severely active ulcerative colitis. Xeljanz is the first oral medication approved for chronic use in this indication.

30 May 2018

NUS researchers find novel pathway to regulate blood pressure

New and better ways to fight hypertension and low blood pressure may be in the offing, thanks to the National University of Singapore scientists' discovery of how our blood pressure is controlled.

30 May 2018

Fewer women meet eligibility criteria for clinical trial of heart failure drugs, study finds

Clinical trial enrolment favors men, according to a study presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. The study found that fewer women meet eligibility criteria for trials of heart failure medication.

28 May 2018

Novoheart announces next generation of 'Human heart-in-a-jar' technology for advanced drug discovery

Novoheart today announced that the next generation of its ‘Human heart-in-a-jar’ technology - which makes up a key component of its comprehensive MyHeartTM Platform - will be unveiled for the first time at the Annual Meeting of the International Society for Stem Cell Research, held in Melbourne, Australia from 20-23 June, 2018.

26 May 2018

Researchers reveal potent new mechanism of action for treatment of IBD

Professor Akiyoshi Fukamizu's research group of Life Science Center for Survival Dynamics, University of Tsukuba, Eisai Co., Ltd. and its gastrointestinal business subsidiary EA Pharma Co., Ltd. have revealed a mechanism in which an analogue (ER-464195-01) of Eisai's in-house discovered E6007 inhibits integrin activation by dissociating interaction between calreticulin (CRT) and integrin α 4 (ITGA4), suppressing adhesion and infiltration of leukocytes overall.

25 May 2018

UAB professor receives award for malaria prevention study in pregnant women in Cameroon

Jodie Dionne-Odom, M.D., assistant professor in the University of Alabama at Birmingham's Division of Infectious Diseases and chief of Women's Health Services at UAB's 1917 Clinic, has been awarded a five-year, $841,000 K23 grant from the National Institute of Child Health and Human Development of the National Institutes of Health.

25 May 2018

BMC receives $13.5 million award to test methods for delivering childhood anxiety treatment

Boston Medical Center has been approved for a $13.5 million award by the Patient-Centered Outcomes Research Institute to test the efficacy of two different methods of delivering cognitive behavioral therapy - face to face or online - to children with anxiety.

25 May 2018

New drug-delivering nanoparticle could offer better way to treat brain tumors

Glioblastoma multiforme, a type of brain tumor, is one of the most difficult-to-treat cancers. Only a handful of drugs are approved to treat glioblastoma, and the median life expectancy for patients diagnosed with the disease is less than 15 months.

25 May 2018

FDA approves novel enzyme therapy for adults with rare and serious genetic disease

The U.S. Food and Drug Administration today approved Palynziq (pegvaliase-pqpz) for adults with a rare and serious genetic disease known as phenylketonuria (PKU).

25 May 2018

Celgene to share new and updated data around novel hematological therapies

Celgene Corporation today announced that data from a broad range of early and late stage studies evaluating Celgene investigational agents and investigational uses of marketed products will be presented at the 23rd European Hematology Association annual meeting in Stockholm, Sweden, from June 14-17, 2018.

22 May 2018

FDA approves new drug to treat thrombocytopenia in adults with chronic liver disease

The U.S. Food and Drug Administration today approved Doptelet (avatrombopag) tablets to treat low blood platelet count (thrombocytopenia) in adults with chronic liver disease who are scheduled to undergo a medical or dental procedure. This is the first drug approved by the FDA for this use.

22 May 2018

Ethics of conducting clinical research during public health emergencies

Following the 2014-2015 Ebola outbreak in West Africa, the U.S. National Academy of Sciences, Engineering and Medicine established a committee to assess the clinical trials conducted in Guinea, Sierra Leone and Liberia.

22 May 2018

Researchers create tool to determine patient's response to immunotherapy drugs

Understanding that not all bladder cancers are the same, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have created a tool that may help them to uncover why only a fraction of patients respond to new immune-based treatments.

21 May 2018

Unique nanotechnology method to simplify skin disease diagnosis

In a new SLAS Technology auto-commentary, two authors of an article recently published in Nature Biomedical Engineering ("Abnormal Scar Identification with Spherical Nucleic Acid Technology" – www.nature.com/articles/s41551-018-0218-x) share more insight into their unique method for skin disease diagnosis using NanoFlare nanotechnology.

21 May 2018

UK military to use Celox Rapid hemostatic gauzes for treating gunshot and stab wounds

Celox Medical has won a new contract with Team Leidos to supply the UK Ministry of Defence with Celox Rapid haemostatic gauzes for use with all branches of the UK military to treat gunshot and stab wounds.

18 May 2018

Chemist begins new project to develop carbohydrate mimics to assist cancer therapies

Dr. Robert Britton firmly believes every molecule is important. This chemist doesn't want any molecule sitting unused on a laboratory shelf or in a fridge.

18 May 2018

FDA OKs first non-opioid drug for adults with opioid withdrawal symptoms

The United States Food and Drugs Administration (FDA), in a statement this week, approved a new drug Lucemyra (lofexidine hydrochloride) for the treatment and alleviation of opioid symptom withdrawal symptoms in adults in whom the drugs have been withdrawn abruptly.

17 May 2018

Pfizer announces Phase 3 study results of LYRICA Oral Solution CV for pediatric epilepsy patients

Pfizer Inc. announced today positive top-line results of a Phase 3 study examining the use of LYRICA® Oral Solution CV as adjunctive therapy for partial onset seizures in pediatric epilepsy patients one month to less than four years of age.

17 May 2018

Doctors publish comprehensive proposal to ensure universal access to safe, affordable medications

The skyrocketing cost of prescription drugs is one of the biggest concerns for American voters. However, in his proposal last Friday, President Donald Trump failed to offer any new policies that would expand access, reduce costs, or increase the safety and efficacy of prescriptions.

17 May 2018

Efficacy News and Research

New system for anti-cancer drug delivery offers hope to treat pediatric tumors

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

NUS researchers find novel pathway to regulate blood pressure

Fewer women meet eligibility criteria for clinical trial of heart failure drugs, study finds

Novoheart announces next generation of 'Human heart-in-a-jar' technology for advanced drug discovery

Researchers reveal potent new mechanism of action for treatment of IBD

UAB professor receives award for malaria prevention study in pregnant women in Cameroon

BMC receives $13.5 million award to test methods for delivering childhood anxiety treatment

New drug-delivering nanoparticle could offer better way to treat brain tumors

FDA approves novel enzyme therapy for adults with rare and serious genetic disease

Celgene to share new and updated data around novel hematological therapies

FDA approves new drug to treat thrombocytopenia in adults with chronic liver disease

Ethics of conducting clinical research during public health emergencies

Researchers create tool to determine patient's response to immunotherapy drugs

Unique nanotechnology method to simplify skin disease diagnosis

UK military to use Celox Rapid hemostatic gauzes for treating gunshot and stab wounds

Chemist begins new project to develop carbohydrate mimics to assist cancer therapies

FDA OKs first non-opioid drug for adults with opioid withdrawal symptoms

Pfizer announces Phase 3 study results of LYRICA Oral Solution CV for pediatric epilepsy patients

Doctors publish comprehensive proposal to ensure universal access to safe, affordable medications

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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