Efficacy News and Research

RSS

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Alexo Therapeutics, a clinical-stage immuno-oncology company developing therapies to block the CD47 checkpoint mechanism, today announced it has initiated ALX148 combination dosing with targeted antibody therapies in its Phase 1 clinical program in patients with advanced solid tumors and lymphoma.

17 May 2018

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Obsidian Therapeutics, Inc., a biotechnology company dedicated to the development of next-generation cell and gene therapies with pharmacologic operating systems, today announced that the company presented preclinical data on its regulated IL12 and IL15 programs at the Annual Meeting of the American Society of Gene and Cell Therapy in Chicago, IL.

17 May 2018

Male depression reduces the chances of getting pregnant, finds new study

A new study has shown that among couples being treated for infertility, male depression was associated with lower pregnancy rates.

17 May 2018

AstraZeneca collaborates with Emulate to integrate Organs-on-Chips technology into drug development labs

Emulate, Inc. has formed a collaborative partnership with AstraZeneca’s Innovative Medicines and Early Development Biotech Unit to embed its Organs-on-Chips technology within the laboratories of the IMED Drug Safety organization.

From AstraZeneca 17 May 2018

New insights regarding challenges in rare disease diagnosis, drug approval, and patient access

Value in Health, the official journal of ISPOR, announced today the publication of a series of articles offering important insight regarding the challenges in rare disease diagnosis, drug approval, and patient access.

17 May 2018

FutureNeuro and GreenLight Medicines team up to develop cannabis-based treatments for epilepsies

A new partnership between FutureNeuro, the SFI Research Centre for Chronic and Rare Neurological diseases based at RCSI and GreenLight Medicines, an indigenous Irish biopharmaceutical company has been formed to develop new cannabis-based treatments for drug-resistant epilepsies, and in particular, childhood epilepsies.

17 May 2018

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

The U.S. Food and Drug Administration today approved Lucemyra (lofexidine hydrochloride) for the mitigation of withdrawal symptoms to facilitate abrupt discontinuation of opioids in adults.

17 May 2018

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

In a recent study published in the Journal of Clinical Investigation, Mayo Clinic researchers identified that an FDA drug approved for myelodysplastic syndrome may be useful to treat triple-negative breast cancer, which is one of the most aggressive and lethal types of breast cancer.

16 May 2018

Clinical study shows promising results of Nexodyn AcidOxidizing Solution in healing chronic wounds

APR Applied Pharma Research sa, the Swiss independent developer of science driven and patent protected healthcare products, today announces the publication in "Advances in skin & wound care" of the results of a clinical pilot study on the efficacy and tolerability of Nexodyn AcidOxidizing Solution, a sprayable Active Cleanser with ancillary antimicrobial activity developed for acute and chronic wound management.

16 May 2018

Emulate partners with AstraZeneca to accelerate development of Organs-on-Chips technology

Emulate, Inc. has formed a collaborative partnership with AstraZeneca's Innovative Medicines and Early Development Biotech Unit to embed its Organs-on-Chips technology within the laboratories of the IMED Drug Safety organization.

16 May 2018

FDA clears Turnstone Biologics' IND for immunotherapy targeting HPV positive solid tumors

Turnstone Biologics today announced it has received U.S. Food and Drug Administration clearance of its Investigational New Drug Application for MG1-HPV for the treatment of patients with human papillomavirus positive solid tumors.

16 May 2018

Study: MRI fusion biopsy outperforms standard prostate biopsy

Researchers at the University of Cincinnati have found that MRI fusion biopsy--coupling MRI and ultrasound to visualize suspicious lesions in the prostate gland and targeting the biopsy to that particular area--outperformed standard prostate biopsy in patients with a prior negative prostate biopsy.

16 May 2018

Scientists uncover new target for MRSA

Researchers at Michigan State University have identified why methicillin-resistant Staphylococcus aureus or MRSA is so resilient, a finding that could pave the way for potential new treatments.

15 May 2018

New study aims to turn MRSA’s strength against it

Antibiotic-resistant infections cause more than 30,000 deaths annually in the U.S. alone. The majority of those are caused by methicillin-resistant Staphylococcus aureus, more commonly known as MRSA, which can turn routine medical operations into near-death battles.

15 May 2018

Researchers reverse Alzheimer's symptoms in flies by restoring epigenetic balance

Researchers from Drexel University reversed symptoms of Alzheimer's disease in fruit flies by restoring the balance between two epigenetic enzymes that regulate gene expression, a study shows.

15 May 2018

New drug reduces symptoms of Rett syndrome in preclinical models

A new article published in the Cell Reports describes how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett Syndrome in preclinical models.

14 May 2018

LogicBio team to present data on preclinical effectiveness of GeneRide platform

LogicBio Therapeutics, Inc., a genetic medicine company founded to develop safe medicines with lasting therapeutic benefit for children with life-threatening diseases, today announced it will be presenting data on the company's technology and robust preclinical pipeline at the annual meeting of the American Society of Gene & Cell Therapy at the Hilton Chicago, from May 16-19, 2018.

14 May 2018

Researchers urge re-examination of colonial models in regulation of traditional medicine practitioners

Two commentaries in JACM, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers that is dedicated to examining paradigm, practice, and policy advancing integrative health, raise questions about whether the value to health care of traditional, complementary, and integrative practices and practitioners is unfairly de-valued by the dominant biomedical model.

14 May 2018

CMS approves national reimbursement coverage for CardiAMP Chronic Myocardial Ischemia Trial

BioCardia, Inc., a leader in the development of comprehensive solutions for cardiovascular regenerative therapies, today announced that the Centers for Medicare and Medicaid Services has approved national reimbursement coverage for the CardiAMP Chronic Myocardial Ischemia Trial.

10 May 2018

Study finds neuroinflammation in spinal cord, nerve roots of patients with chronic sciatica

A study by Massachusetts General Hospital investigators has found, for the first time in humans, that patients with chronic sciatica - back pain that shoots down the leg - have evidence of inflammation in key areas of the nervous system.

10 May 2018

Efficacy News and Research

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Male depression reduces the chances of getting pregnant, finds new study

AstraZeneca collaborates with Emulate to integrate Organs-on-Chips technology into drug development labs

New insights regarding challenges in rare disease diagnosis, drug approval, and patient access

FutureNeuro and GreenLight Medicines team up to develop cannabis-based treatments for epilepsies

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

Clinical study shows promising results of Nexodyn AcidOxidizing Solution in healing chronic wounds

Emulate partners with AstraZeneca to accelerate development of Organs-on-Chips technology

FDA clears Turnstone Biologics' IND for immunotherapy targeting HPV positive solid tumors

Study: MRI fusion biopsy outperforms standard prostate biopsy

Scientists uncover new target for MRSA

New study aims to turn MRSA’s strength against it

Researchers reverse Alzheimer's symptoms in flies by restoring epigenetic balance

New drug reduces symptoms of Rett syndrome in preclinical models

LogicBio team to present data on preclinical effectiveness of GeneRide platform

Researchers urge re-examination of colonial models in regulation of traditional medicine practitioners

CMS approves national reimbursement coverage for CardiAMP Chronic Myocardial Ischemia Trial

Study finds neuroinflammation in spinal cord, nerve roots of patients with chronic sciatica

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News