Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Researchers find unexpected connection between two types of calming immune cells

Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection--and all that separates us from these foreign entities is a delicate boundary made of a single layer of cells.

15 Jun 2016

Researcher employs high-resolution imaging, mechanical mapping to gauge structural integrity of cornea

A biomedical engineer at the University of Houston is developing new techniques to map the structural integrity of the human cornea, work that could lead to more effective therapies for degenerative corneal disease.

15 Jun 2016

Anti-TNF therapy offers new hope to JDM patients

The results of a UK study presented today at the European League Against Rheumatism Annual Congress showed that tumour necrosis factor inhibitor (anti-TNF) treatment is effective at improving both muscle and skin involvement in children with juvenile dermatomyositis (JDM).

13 Jun 2016

Researchers find link between specific genetic pathway and development of mouth ulcers in lupus patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed for the first time an association between a specific genetic pathway and the development of mouth ulcers in patients with Systemic Lupus Erythematosus (SLE).

13 Jun 2016

Study opens up possibility of developing potential hormone therapies for SSc skin disease

The results of a study presented today at the European League Against Rheumatism Annual Congress showed for the first time a beneficial effect of oestrogens in experimental models of skin fibrosis that are representative of the disease process in systemic sclerosis (SSc).

13 Jun 2016

Autoimmune diseases among lung cancer patients may make them unsuitable for immunotherapy

A significant proportion of lung cancer patients also have autoimmune disease, which may make them unsuitable for increasingly popular immunotherapy treatments, a team of researchers at UT Southwestern Medical Center's Harold C. Simmons Comprehensive Cancer Center has found.

6 Jun 2016

Scientists discover master dimmer switches that control activity of immune cells

A person's genetic makeup plays a role in autoimmune diseases such as multiple sclerosis that develop when the body is attacked by its own immune system. But little is known about how immune cells are pushed into overdrive.

3 Jun 2016

TxCell, LIED collaborate to develop CAR-Treg-based cellular immunotherapy for bullous pemphigoid

TxCell SA, a biotechnology company developing innovative, personalized cellular immunotherapies using regulatory T cells to treat severe chronic inflammatory and autoimmune diseases, today announces the signature of a strategic R&D collaboration agreement with the Lübeck Institute of Experimental Dermatology, a leading institution in the field of translational research on skin blistering diseases, part of the University of Lübeck in Germany.

2 Jun 2016

New study sheds light on link between gut microbiome and the brain

Intestinal bacteria that can boost bravery or trigger multiple sclerosis: An increasing body of research results confirms the importance of the "gut-brain axis" for neurology and indicates that the triggers for a number of neurological diseases may be located in the digestive tract.

30 May 2016

Zinbryta gets FDA approval for treating adults with relapsing forms of MS

The U.S. Food and Drug Administration today approved Zinbryta (daclizumab) for the treatment of adults with relapsing forms of multiple sclerosis (MS). Zinbryta is a long-acting injection that is self- administered by the patient monthly.

28 May 2016

Novel way of directly activating Bak protein can trigger cell death

Melbourne researchers have discovered a new way of triggering cell death, in a finding that could lead to drugs to treat cancer and autoimmune disease.

27 May 2016

Fasting-mimicking diet may help decrease multiple sclerosis symptoms

Evidence is mounting that a diet mimicking the effects of fasting has health benefits beyond weight loss, with a new USC-led study indicating that it may reduce symptoms of multiple sclerosis.

27 May 2016

Personalized DXM-loaded leukosomes may help treat inflammation

Nanosized Trojan horses created from a patient's own immune cells have successfully treated inflammation by overcoming the body's complex defense mechanisms, perhaps leading to broader applications for treating diseases characterized by inflammation, such as cancer and cardiovascular diseases.

24 May 2016

Research provides pathway toward creation of first broad-spectrum antiviral drug

By studying the rare person -- about one in a million -- who can fight off viral infections more effectively than everyone else, investigators at the Icahn School of Medicine at Mount Sinai have developed a strategy to help the rest of us achieve this enhanced anti-viral state.

21 May 2016

Study links multiple sclerosis in children to abundance of specific gut bacteria

In a recent study, children with multiple sclerosis had differences in the abundance of specific gut bacteria than children without the disease. Certain types of bacteria were either more or less abundant in children with multiple sclerosis.

17 May 2016

Researchers reveal new mechanism that helps breast cancer cells engage MDSCs

Not every breast cancer tumor follows the same path to grow. Some tumors have the assistance of myeloid-derived suppressor cells (MDSCs), a diverse type of immune cell involved in the suppression of the body's response against tumors.

17 May 2016

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Researchers at Beth Israel Deaconess Medical Center have identified an enzyme that is significantly elevated in mouse models of systemic lupus erythematosus and in blood samples of patients with lupus.

17 May 2016

Common misconceptions regarding gluten-free diet for children

The prevalence of celiac disease (CD), an autoimmune disease, is increasing. The only treatment for CD is a gluten-free diet. However, the increasing prevalence of CD does not account for the disproportionate increase in growth of the gluten-free food industry (136% from 2013 to 2015).

13 May 2016

Scientists visualize apoptosis in live zebrafish using FLIM OPT method

A promising approach for watching cell signaling processes in their physiological context: Scientists visualize apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time.

11 May 2016

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

In most cases, tumors of the thymus gland are removed by surgical resection. However, they recur after a few years in up to one third of patients. A research team headed up by thoracic surgeon Bernhard Moser of the Thoracic Surgery Department at MedUni Vienna has successfully demonstrated that these tumors form heat-shock proteins. The lower the concentration of these proteins, the more quickly tumors recur. The study has been published in the leading journal Scientific Reports.

10 May 2016

Autoimmune Disease News and Research

Further Reading

Researchers find unexpected connection between two types of calming immune cells

Researcher employs high-resolution imaging, mechanical mapping to gauge structural integrity of cornea

Anti-TNF therapy offers new hope to JDM patients

Researchers find link between specific genetic pathway and development of mouth ulcers in lupus patients

Study opens up possibility of developing potential hormone therapies for SSc skin disease

Autoimmune diseases among lung cancer patients may make them unsuitable for immunotherapy

Scientists discover master dimmer switches that control activity of immune cells

TxCell, LIED collaborate to develop CAR-Treg-based cellular immunotherapy for bullous pemphigoid

New study sheds light on link between gut microbiome and the brain

Zinbryta gets FDA approval for treating adults with relapsing forms of MS

Novel way of directly activating Bak protein can trigger cell death

Fasting-mimicking diet may help decrease multiple sclerosis symptoms

Personalized DXM-loaded leukosomes may help treat inflammation

Research provides pathway toward creation of first broad-spectrum antiviral drug

Study links multiple sclerosis in children to abundance of specific gut bacteria

Researchers reveal new mechanism that helps breast cancer cells engage MDSCs

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Common misconceptions regarding gluten-free diet for children

Scientists visualize apoptosis in live zebrafish using FLIM OPT method

Study links lower concentration of heat-shock proteins to recurrence of thymic tumors

Understanding the DNA Damage Response in Innate Immunity eBook

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