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New dual drugs eliminate tumors when combined with immunotherapy

Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of novel, first-in-class drugs that inhibit hypoxia-inducible factors 1 and 2, a pair of transcription factors considered to be "master regulators" of cancer progression.

2 Apr 2026

International researchers set new standards for studying tumor microbiota

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

2 Apr 2026

State-run insurance plans for foster kids leave some of them without doctors

Ollie Super has moved in and out of cancer treatment since she was diagnosed with neuroblastoma as a toddler in foster care. Now 8, the second grader is dealing with it again. Her cancer came back late last year.

2 Apr 2026

Celiac disease weakens gut microbes that digest fiber

Findings suggest that impaired fiber metabolism in celiac disease is due to microbial deficits, not just diet, emphasizing the need for targeted interventions.

2 Apr 2026

Wegovy® (semaglutide injection) 2.4 mg recommended by NICE to reduce risk of major adverse cardiovascular events, including heart attacks and strokes, in adults with established cardiovascular disease and overweight or obesity (BMI ≥ 27 kg/m2)

NICE has recommended Wegovy® (semaglutide injection) 2.4 mg as the first GLP-1 RA to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established cardiovascular disease and either obesity or overweight (BMI ≥ 27 kg/m2).

From Novo Nordisk 2 Apr 2026

NCCN conference highlights advances in global cancer care strategies

The National Comprehensive Cancer Network® (NCCN®)-a non-profit alliance of leading cancer centers-brought together more than a thousand oncology professionals at the NCCN 2026 Annual Conference in Orlando, Florida, with hundreds more joining virtually.

1 Apr 2026

Trial tests fast-acting brain stimulation for postpartum depression treatment

The Icahn School of Medicine at Mount Sinai today announced the enrollment of its first patient in a U.S. Department of Defense-funded pivotal clinical trial to evaluate whether a fast-acting, drug-free brain stimulation therapy can safely and quickly relieve symptoms of postpartum depression.

1 Apr 2026

Gene-edited treatment shows promising outcomes for severe sickle cell disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

1 Apr 2026

Heat-activated patch shows promise for noninvasive melanoma treatment

Melanoma is a deadly form of skin cancer that is typically removed surgically. Now, researchers publishing in ACS Nano report they have developed a potential noninvasive treatment for melanoma in the form of a stretchy, heat-activated patch similar to a bandage.

1 Apr 2026

ASH releases updated recommendations for severe acquired aplastic anemia care

The American Society of Hematology (ASH) released guidelines on the diagnosis and management of severe acquired aplastic anemia, a rare and life-threatening bone marrow failure disorder.

1 Apr 2026

Highly potent opioid shows potential as therapy for pain and opioid use disorder

Researchers at the National Institutes of Health (NIH) have identified a novel, highly potent opioid that shows potential as a therapy for both pain and opioid use disorder.

1 Apr 2026

Molecular switch in neurons found to limit the regrowth of damaged axonal fibers

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

1 Apr 2026

"Smart" system distinguishes and neutralizes cancer cells with unprecedented precision

A team from UNIGE has designed a molecular system that distinguishes and neutralizes cancer cells with unprecedented precision, paving the way for autonomous, self-regulating drugs.

1 Apr 2026

Experts unveil new imaging standards for heart procedures

The global community of heart rhythm specialists will unite in Paris from 12 to 14 April 2026 for EHRA 2026, the annual congress of the European Heart Rhythm Association (EHRA), a branch of the European Society of Cardiology (ESC).

1 Apr 2026

PRISM ALS: A new global collaboration to expand patient-derived stem cell models and accelerate treatments

A new global initiative launched today aims to close a critical gap in ALS/MND drug discovery - current cell models used for testing treatments do not currently reflect the diverse nature of the disease - that affects both researchers developing therapies and the people urgently waiting for them.

From ALS Therapy Development Institute (ALS TDI) 1 Apr 2026

Machine learning helps predict risks during stem cell therapy for myeloma

Multiple myeloma is a cancer in which plasma cells, which normally produce antibodies, multiply uncontrollably in the bone marrow.

31 Mar 2026

Study reveals how extracellular matrix stiffness regulates breast cancer metastasis

A study by researchers at the University of California San Diego could make it easier to treat breast cancer by uncovering a new way the body helps prevent its spread.

31 Mar 2026

Novel compound clears harmful protein, protects neurons in frontotemporal dementia models

New research from Washington University School of Medicine in St. Louis adds to growing evidence that helping brain cells break down and eliminate their own cellular waste is a promising treatment strategy for a variety of neurodegenerative diseases.

31 Mar 2026

Treating autonomic dysfunction can relieve symptoms of treatment-resistant depression

Consider a house with the water main half shut. The faucets sputter. The toilet runs all night. The garden wilts. You could call a plumber for the faucet, a landscaper for the garden, a different plumber for the toilet, and every one of them would fix something while fixing nothing.

31 Mar 2026

New stem cell therapy offers permanent cure for Hirschsprung disease

Scientists are developing a revolutionary new stem cell therapy to treat a rare and life-threatening disease that leaves newborn babies unable to function without invasive surgery, thanks to a collaboration between UCL, the University of Sheffield and Queen's University Belfast.

31 Mar 2026

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Therapy News and Research

New dual drugs eliminate tumors when combined with immunotherapy

International researchers set new standards for studying tumor microbiota

State-run insurance plans for foster kids leave some of them without doctors

Celiac disease weakens gut microbes that digest fiber

Wegovy® (semaglutide injection) 2.4 mg recommended by NICE to reduce risk of major adverse cardiovascular events, including heart attacks and strokes, in adults with established cardiovascular disease and overweight or obesity (BMI ≥ 27 kg/m2)

NCCN conference highlights advances in global cancer care strategies

Trial tests fast-acting brain stimulation for postpartum depression treatment

Gene-edited treatment shows promising outcomes for severe sickle cell disease

Heat-activated patch shows promise for noninvasive melanoma treatment

ASH releases updated recommendations for severe acquired aplastic anemia care

Highly potent opioid shows potential as therapy for pain and opioid use disorder

Molecular switch in neurons found to limit the regrowth of damaged axonal fibers

"Smart" system distinguishes and neutralizes cancer cells with unprecedented precision

Experts unveil new imaging standards for heart procedures

PRISM ALS: A new global collaboration to expand patient-derived stem cell models and accelerate treatments

Machine learning helps predict risks during stem cell therapy for myeloma

Study reveals how extracellular matrix stiffness regulates breast cancer metastasis

Novel compound clears harmful protein, protects neurons in frontotemporal dementia models

Treating autonomic dysfunction can relieve symptoms of treatment-resistant depression

New stem cell therapy offers permanent cure for Hirschsprung disease

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