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Novel assay shows potential to detect circulating cancer biomarkers in blood samples

Future Science Group today announced the publication of an article in Future Science OA presenting early data from a novel assay for the non-invasive detection of PD-L1 and other biomarkers in patient blood samples.

22 Sep 2017

Researchers discover mechanism of drug resistance for ovarian and breast cancer cells

Researchers from the People's Friendship University of Russia have studied the mechanism of drug resistance for ovarian and breast cancer cells.

22 Sep 2017

Alternative splicing may also trigger cancer, study shows

Cancer, which is one of the leading causes of death worldwide, arises from the disruption of essential mechanisms of the normal cell life cycle, such as replication control, DNA repair and cell death.

22 Sep 2017

Diet and exercise have potential to improve chemotherapy effectiveness in pediatric cancer patients

Diet and exercise may improve treatment outcomes in pediatric cancer patients, according to a study at The University of Texas MD Anderson Children's Cancer Hospital.

21 Sep 2017

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Inspired by the Labyrinth of Greek mythology, a new chip etched with fluid channels sends blood samples through a hydrodynamic maze to separate out rare circulating cancer cells into a relatively clean stream for analysis. It is already in use in a breast cancer clinical trial.

21 Sep 2017

Researchers identify molecular pathway that causes immune cells to promote cancer

Investigators at the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles have identified new findings about an immune cell - called a tumor-associated macrophage - that promotes cancer instead of fighting it.

21 Sep 2017

Indiana University awarded $4 million NSF grant to advance nanoscale medical devices

Only a year after establishing the intelligent systems engineering program in the Indiana University School of Informatics, Computing and Engineering, the university has been awarded a five-year, $4 million grant from the National Science Foundation to advance nanoscale devices to improve human health, including fighting cancer.

21 Sep 2017

Forgotten strands of DNA induce 'big bang' of immune cell development

Intricate human physiological features such as the immune system require exquisite formation and timing to develop properly. Genetic elements must be activated at just the right moment, across vast distances of genomic space.

21 Sep 2017

Study identifies slowly proliferating and highly invasive melanoma cells

A study conducted at The Wistar Institute has led to the identification of a slowly proliferating and highly invasive melanoma cell subpopulation, characterized by production of a protein associated with invasive behavior. The research was published in the journal Oncogene.

21 Sep 2017

Study opens new door to potential treatments for highly lethal brain tumors

New research conducted in mice provides evidence that highly lethal brain tumors, called high-grade gliomas, stop growing when deprived of a specific molecule naturally produced when brain cells fire.

21 Sep 2017

UConn Health makes new 3D-printed model of arteries to help surgeons get practice

The first time a young surgeon threads a wire through a stroke victim's chest up through their neck and fishes a blood clot out of their brain may be one of the most harrowing moments in her career.

21 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

Poliovirus therapy triggers longer-lasting immune response against malignant tumors

An investigational therapy using modified poliovirus to attack cancer tumors appears to unleash the body's own capacity to fight malignancies by activating an inflammation process that counter's the ability of cancer cells to evade the immune system.

20 Sep 2017

Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant to treatment.

20 Sep 2017

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Researchers at the Spanish National Cancer Research Centre have discovered a genetic alteration that is directly involved in at least 10% of cases of one of the most common cancers in children, T-cell acute lymphoblastic leukemia.

20 Sep 2017

Researchers propose new treatment strategy for colon cancer patients

Colorectal cancer is the fourth leading cause of cancer-related deaths worldwide. In a new study, researchers demonstrate for the first time that a previously uncharacterized protein is increased in colon cancer. The protein is immunoglobulin containing proline rich receptor-1 (IGPR-1) which was recently identified in the same laboratory as a cell adhesion molecule.

20 Sep 2017

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

In a multi-institutional collaborative study, scientists at The Wistar Institute and the Medical University of Vienna, Austria, have identified the role of tumor-infiltrating or tumor-associated B-cells ("TABs") in melanoma progression and resistance to targeted therapy.

20 Sep 2017

Researchers develop new model to better simulate blood brain barrier for study of diseases

Scientists have helped provide a way to better understand how to enable drugs to enter the brain and how cancer cells make it past the blood brain barrier. The brain is protected by the near-impermeable blood brain barrier, a fortress which protects the brain but which also prevents the treatment of brain diseases, including brain tumors.

19 Sep 2017

Cholesterol-like molecules act as ‘cut-off’ switch for engine that powers cancer-killing cells

Scientists have just discovered how the engine that powers cancer-killing cells functions. Crucially, their research also highlights how that engine is fuelled and that cholesterol-like molecules, called oxysterols, act as a "cut-off" switch making it hard for our 'Natural Killer' cells to win the war against cancer.

19 Sep 2017

Salk study shows how fast-growing tumors evade immune system

The immune system automatically destroys dysfunctional cells such as cancer cells, but cancerous tumors often survive nonetheless. A new study by Salk scientists shows one method by which fast-growing tumors evade anti-tumor immunity.

18 Sep 2017

Tumor News and Research

Novel assay shows potential to detect circulating cancer biomarkers in blood samples

Researchers discover mechanism of drug resistance for ovarian and breast cancer cells

Alternative splicing may also trigger cancer, study shows

Diet and exercise have potential to improve chemotherapy effectiveness in pediatric cancer patients

'Labyrinth' chip may be new way to monitor cancer patients in clinical trials

Researchers identify molecular pathway that causes immune cells to promote cancer

Indiana University awarded $4 million NSF grant to advance nanoscale medical devices

Forgotten strands of DNA induce 'big bang' of immune cell development

Study identifies slowly proliferating and highly invasive melanoma cells

Study opens new door to potential treatments for highly lethal brain tumors

UConn Health makes new 3D-printed model of arteries to help surgeons get practice

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

Poliovirus therapy triggers longer-lasting immune response against malignant tumors

Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Researchers propose new treatment strategy for colon cancer patients

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

Researchers develop new model to better simulate blood brain barrier for study of diseases

Cholesterol-like molecules act as ‘cut-off’ switch for engine that powers cancer-killing cells

Salk study shows how fast-growing tumors evade immune system

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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