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New study maps early molecular changes in jaw joint osteoarthritis

Temporomandibular joint disorders (TMDs) affect a large portion of the global population and are a common source of chronic jaw pain and difficulty in chewing or speaking.

23 Apr 2026

Rural and urban children face distinct mental health challenges

A study in Pediatric Investigation found that rural and urban children and adolescents tend to experience different mental health issues, with those living in the country showing more emotional problems and those in the city demonstrating more behavioral issues.

22 Apr 2026

Common gene in axolotls, mice and zebrafish may unlock human limb regrowth

Investigating a common gene in three very different species – axolotls, mice and zebrafish – scientists have discovered the potential for a novel gene therapy aimed at eventually regrowing limbs in humans, according to new research published this week.

21 Apr 2026

A new method to measure intracellular water in biological systems

Teemu Miettinen discusses his innovative method for measuring intracellular water, revealing its critical role in cell function and disease mechanisms.

21 Apr 2026

New study reveals CRISPR enzyme that responds to human DNA methylation

Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of scientists from Wageningen University & Research and Van Andel Institute has identified a way to exploit this distinction. Using a variant of CRISPR, a modern tool for editing DNA, they distinguished tumor DNA from healthy DNA and selectively cut only the former. The study, published today in Nature, is an early but promising step toward a cancer therapy that targets and destroys tumor cells with high precision.

20 Apr 2026

Researchers discover how stress signals weaken the aging immune system

As we age, our ability to maintain healthy blood and a strong immune system gradually declines, largely because hematopoietic stem cells (HSCs), the cells responsible for producing all blood cell types, begin to lose their effectiveness. Normally, HSCs can both self-renew and generate a balanced mix of blood cells, but over time they produce fewer new cells, favor certain cells such as myeloid cells over lymphoid cells, and struggle to support a robust immune response.

16 Apr 2026

Study explains failure of cellular cleanup in neurodegenerative diseases

Inside every cell, a cleanup operation runs around the clock. Proteins are constantly damaged by wear and tear. Some can be repaired, while others must be dismantled and recycled.

15 Apr 2026

New CRISPR tool selectively cuts tumor DNA while sparing healthy cells

Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells.

15 Apr 2026

AP-1 proteins help cancer cells rewire genes to survive treatment

A long-standing mystery in cancer treatment is how tumor cells so often become resistant to drugs, even ones they have never encountered before.

15 Apr 2026

VALANX Biotech establishes Scientific Advisory Board to advance ADC therapeutics

VALANX Biotech (VALANX), a biotech company developing novel technology for site-specific protein conjugation in drug discovery, today announced the formation of its Scientific Advisory Board (SAB), appointing John Lambert as Chair, with Morris Rosenberg and Peter de Waele serving alongside.

From VALANX Biotech 15 Apr 2026

Korean skincare ingredient emerges as potential antibiotic candidate

Fans of Korean skincare may be familiar with 'hero ingredient' Madecassic acid for its skin-soothing properties, but researchers at the University of Kent have revealed its greater potential for use in the battle against antibiotic resistance.

9 Apr 2026

Study outlines principles for using CAR immunotherapies to treat neurodegenerative diseases

A UAB research team defines the criteria that CAR immunotherapies for neurodegenerative diseases must meet to advance both conceptually and in trials, which are still at a very preliminary stage, in a review study published in the journal Trends in Pharmacological Sciences.

8 Apr 2026

CIPHER-seq technology reveals how immune cells communicate during treatment

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

8 Apr 2026

Novel screening method boosts early diagnosis of leprosy

A new blood test combined with a standardized questionnaire and artificial intelligence may transform the way leprosy is diagnosed in Brazil. Researchers at the University of São Paulo (USP) tested the new test in Brazil using blood samples collected during a COVID-19 population survey.

6 Apr 2026

Mayo Clinic researchers develop experimental nanotherapy to treat aggressive brain tumors

Mayo Clinic researchers developed an experimental nanotherapy that delivers two cancer drugs directly to brain tumors, according to a study published in Communications Medicine.

6 Apr 2026

Study reveals how bacterial collagenase efficiently breaks down collagen

Collagen is an important protein that helps build the tissues of humans and animals. It is very strong because it is made of three protein strands twisted tightly together like a rope. Because of this sturdy structure, ordinary protein-cutting enzymes usually cannot break it down.

3 Apr 2026

"Smart" system distinguishes and neutralizes cancer cells with unprecedented precision

A team from UNIGE has designed a molecular system that distinguishes and neutralizes cancer cells with unprecedented precision, paving the way for autonomous, self-regulating drugs.

1 Apr 2026

How the nutrient cysteine controls cancer-fighting power of T cells

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health have discovered how the immune system's CD8+ T cells use the nutrient cysteine to control two essential functions that compete for this resource - the immune cell's ability to multiply and its ability to kill cancer cells.

31 Mar 2026

The molecular mechanism that turns cool temps into nerve signals

When you reach into a bucket of ice, open your front door on a snowy day, or feel the tingle of menthol toothpaste, a protein in your nerve cells called TRPM8 springs into action, opening like a tiny gate to send a "cold" signal to your brain.

26 Mar 2026

Can camel milk improve health? Review highlights benefits but warns against drinking it raw

A narrative review in Food Science & Nutrition examined studies published from 2000 to 2025 and found that camel milk contains bioactive compounds with potential glycemic, anti-inflammatory, gut, and other health benefits. It also stressed that raw, unpasteurized camel milk poses microbial and zoonotic risks, underscoring that safety remains a key part of the story.

25 Mar 2026