Cell Line News and Research

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Changes to intermediate filament protein drive aggressive breast cancer growth

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner.

11 Feb 2025

E64FC26 inhibits inflammation and joint destruction in rheumatoid arthritis models

Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the endoplasmic reticulum.

10 Feb 2025

New microscopy technique offers affordable way to study cancer cell metabolism

Understanding how tumors change their metabolism to resist treatments is a growing focus in cancer research.

3 Feb 2025

Researchers create random versions of human genomes to study disease

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

31 Jan 2025

Sphere Fluidics launches Cyto-Mine Chroma and announces Early Access Program

Sphere Fluidics, a leading provider of innovative picodroplet-based microfluidics solutions for functional single cell analysis and isolation, today announced the launch of Cyto-Mine® Chroma and the opening of its Early Access Program at SLAS2025 International Conference and Exhibition in San Diego.

27 Jan 2025

Study reveals impact of fava bean proteins on sensory cells in the mouth

Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have for the first time investigated how protein structures derived from fava beans affect a cellular model of human oral tactile cells.

25 Jan 2025

A new strategy for enhancing the production of protein-based drugs

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

15 Jan 2025

Short-chain fatty acids propionate and butyrate directly modify chromatin to regulate gene expression

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer and normal cellular processes.

13 Jan 2025

Breakthrough microscopy technique reveals how antibodies target cancer cells

In blood cancers such as chronic lymphocytic leukaemia, B cells of the immune system multiply uncontrollably.

10 Jan 2025

New insights into glioblastoma resistance to temozolomide

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used as the front-line medicine in its treatment.

19 Dec 2024

Targeted gene therapy shuts down cancer cells' energy centers

Researchers are shining a light on cancer cells' energy centers – literally – to damage these power sources and trigger widespread cancer cell death.

14 Dec 2024

Beckman Coulter Life Sciences Accelerates Drug Discovery with Launch of Cydem VT Automated Clone Screening System

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From Beckman Coulter Life Sciences - Flow Cytometry 3 Dec 2024

IL-15 improves the effectiveness of GPC3 CAR T cells in targeting solid tumors

The study reveals IL-15's role in enhancing GPC3 CAR T cell therapy, improving tumor targeting and T cell survival in patients with solid cancers.

2 Dec 2024

Asimov and RevOpsis Therapeutics sign licensing agreement for high titer multispecific-expressing cell line

Asimov, the synthetic biology company advancing the design and manufacture of therapeutics, today announced a licensing agreement for its CHO Edge System with RevOpsis Therapeutics ("RevOpsis"), a next-generation biopharmaceutical company spearheading innovation of multispecific biologics in ophthalmic therapies

From Asimov 25 Nov 2024