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Scientists show gut bacteria can reach the brain in mice and reveal a potential vagus nerve pathway

Researchers found that very small numbers of gut bacteria can translocate to the brain in mice, particularly when gut barrier permeability increases due to a Paigen diet. Evidence suggests the vagus nerve may serve as a partial route for this gut-to-brain microbial movement.

15 Mar 2026

Study identifies immune cells and RANK protein as fertility regulators

The kick off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a hormone that activates the hypophysis, at the base of the skull, which then releases other hormones to start gonad –ovaries or testicles –maturation.

12 Mar 2026

Study finds treatment gap for young ADHD patients with substance use disorders

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, affecting 12%–13% of adolescents in the United States, according to some studies.

12 Mar 2026

The 0.05 EU/mg breakthrough: How Sino Biological ProPure™ is redefining the Ultra-Low Endotoxin standard

When we discuss bacterial infections, we often think of exotoxins—those soluble proteins actively secreted by bacteria—while overlooking endotoxins, which are more insidious but equally dangerous.

From Sino Biological Inc. 12 Mar 2026

Does coffee disrupt sleep? Large population study suggests the impact may be minimal

A large cross-sectional analysis of 25,381 Swedish adults aged 50–64 found that habitual coffee consumption showed only very weak associations with sleep quality and daytime sleepiness. Genetic analyses confirmed known coffee-related variants and suggested that long-term caffeine exposure may lead to adaptation in the brain’s adenosine signaling system.

11 Mar 2026

ADHD prescriptions surged during the COVID-19 pandemic

A study reveals COVID-19 reshaped stimulant prescribing patterns in Ontario, highlighting increased ADHD diagnoses and concerns over treatment appropriateness.

11 Mar 2026

Scientists identify common molecular program across multiple brain tumor types

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program.

6 Mar 2026

Single dose of CAR-astrocyte therapy halves amyloid levels in mice brains

The new generation of Alzheimer's disease drugs - the first proven to change the course of the disease - typically extend independent living for patients by 10 months.

6 Mar 2026

MIMETAS publishes breakthrough study on 3D blood-brain barrier model with unidirectional flow

Scientists at MIMETAS have published a new study describing a scalable, self-assembling human blood-brain barrier (BBB) model that combines physiological relevance with high-throughput capability.

5 Mar 2026

AI trained on 9 trillion DNA letters predicts harmful mutations and designs new genomes

Scientists developed Evo 2, a large biological foundation model trained on about 9 trillion DNA base pairs that can analyse genomic sequences across bacteria, plants, and humans. The model predicts functional effects of genetic variants and can generate genome-scale DNA sequences, enabling new approaches to studying and designing biological systems.

5 Mar 2026

Researchers propose that Parkinson’s disease may start in the gut, not the brain

A perspective in The Journal of Clinical Investigation argues that environmental exposures may interact with the gut microbiome and intestinal barrier to trigger biological processes linked to Parkinson’s disease. The authors propose that cumulative environmental stressors can erode host resilience, promoting α-synuclein pathology, immune activation, and neurodegeneration.

5 Mar 2026

New blood biomarker may detect Alzheimer’s pathology more accurately

Researchers compared total plasma pTau217 with a brain-derived pTau217 assay to determine which better identifies Alzheimer’s disease–related amyloid and tau pathology. Brain-derived pTau217 showed strong diagnostic performance and appeared less affected by kidney dysfunction, supporting its potential as a more specific blood biomarker for Alzheimer’s disease.

3 Mar 2026

Investigating microglia’s role in Alzheimer’s pathology

Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia worldwide. Microglia, as central nervous system (CNS) resident macrophages, are key to AD pathology. Indeed, microglia aggregation around amyloid-β (Aβ) deposits is an AD hallmark.

1 Mar 2026

Acoziborole receives positive opinion for single-dose sleeping sickness treatment

The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has granted a positive opinion to Acoziborole Winthrop (acoziborole) as a single-dose oral treatment for both early- and advanced-stage gambiense sleeping sickness in adults as well as in adolescents 12 years and older weighing at least 40 kilograms.

27 Feb 2026

Study finds sharp drop in benzodiazepine use among older adults

Benzodiazepine treatment declined among U.S. adults between 2018 and 2022, with the steepest drop among adults ages 56 and older, according to a new study by researchers at the Columbia University Mailman School of Public Health and Columbia University Irving Medical Center.

25 Feb 2026

Stereotactic radiation improves quality of life in patients with brain metastases

In a Phase 3 randomized trial, Mass General Brigham researchers found that stereotactic radiation targeting individual tumors led to lower symptom burden, better cognitive outcomes, and better day to day function when compared with whole brain radiation

19 Feb 2026

Central Nervous System News and Research

Scientists show gut bacteria can reach the brain in mice and reveal a potential vagus nerve pathway

Study identifies immune cells and RANK protein as fertility regulators

Study finds treatment gap for young ADHD patients with substance use disorders

The 0.05 EU/mg breakthrough: How Sino Biological ProPure™ is redefining the Ultra-Low Endotoxin standard

Does coffee disrupt sleep? Large population study suggests the impact may be minimal

ADHD prescriptions surged during the COVID-19 pandemic

Scientists identify common molecular program across multiple brain tumor types

Single dose of CAR-astrocyte therapy halves amyloid levels in mice brains

MIMETAS publishes breakthrough study on 3D blood-brain barrier model with unidirectional flow

AI trained on 9 trillion DNA letters predicts harmful mutations and designs new genomes

Researchers propose that Parkinson’s disease may start in the gut, not the brain

New blood biomarker may detect Alzheimer’s pathology more accurately

Investigating microglia’s role in Alzheimer’s pathology

Acoziborole receives positive opinion for single-dose sleeping sickness treatment

Study finds sharp drop in benzodiazepine use among older adults

Stereotactic radiation improves quality of life in patients with brain metastases

Key protein regulates slow oxytocin release in the brain

IFN-γ identified as a powerful blood biomarker for Alzheimer’s

Novel implant delivers tiny growth-promoting particles directly to injured nerve cells

A simple handgrip test reveals how strong your working memory may be

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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