Liquid Chromatography News and Research

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Leveraging the Radian ASAP in standard casework

Explore how the Radian ASAP mass spectrometer is being used to streamline and enhance seized drug screening.

From Waters Advanced Diagnostics 30 Apr 2025

Gut bacteria and metabolites reveal depression-linked patterns in older adults

A cross-sectional study of 400 older adults with metabolic syndrome reveals that individuals with depression have distinct gut microbiota and metabolite profiles. Eight bacterial genera and 15 fecal metabolites were significantly associated with depression, suggesting a gut-brain axis link.

29 Apr 2025

Obesity changes how the gut responds to plant compounds, researchers report

Researchers found that the impact of polyphenols rutin and genistein on the human fecal metabolome varies significantly by body mass index (BMI). Lower BMI individuals showed more diverse metabolic responses, revealing how gut health and obesity could shape polyphenol metabolism.

28 Apr 2025

Plastic additives found in 85% of foods raise concern for infant health

Researchers assessed plasticizer levels in foods typical of the Spanish diet and found widespread contamination, with infants showing the highest exposure. Certain additives, like DEHP, exceeded safety thresholds in high-exposure scenarios.

21 Apr 2025

What sauerkraut can do for your gut

Fermented cabbage metabolites play a crucial role in maintaining gut barrier function, suggesting potential health benefits for inflammatory disorders.

16 Apr 2025

Vitamin C from fresh foods helps lower heart disease risk in type 2 diabetes

Low vitamin C levels are linked to higher cardiovascular disease prevalence in people with type 2 diabetes. Fresh fruit and vegetable intake is associated with higher vitamin C levels and may offer protective cardiovascular effects.

7 Apr 2025

Study shows red wine biomarkers in urine can predict inflammation levels

Researchers found that specific metabolites of resveratrol in urine accurately reflect red wine consumption. These biomarkers were linked to reduced inflammation in older adults at cardiovascular risk, unlike traditional food surveys.

25 Mar 2025

Why Mānuka isn't the only healing honey from New Zealand anymore

New research from Auckland University of Technology reveals that eight native New Zealand honeys, beyond mānuka, possess unique antioxidant, antibacterial, and bioactive properties. Thyme and beech honeydew stood out for their vitamin C and polyphenol content.

25 Mar 2025

AI predicts biological aging using steroid pathways

Researchers discuss a novel method to predict biological aging using a deep neural network based on pathways of steroidogenesis.

19 Mar 2025

Apple peels beat some diabetes drugs at blocking blood sugar spikes

Researchers found that apple peels from local and commercial varieties are rich in phenolic compounds with antioxidant and antidiabetic properties. The local cultivar Amarilla de Octubre showed the highest bioactivity, suggesting potential for nutraceutical and pharmaceutical applications.

12 Mar 2025

Cheese isn't just food—it’s a microbiome booster, study confirms

Scientists reveal that cheese-derived bacteria, particularly less abundant strains, can shape gut microbiota and enhance metabolic functions, underscoring the impact of fermented foods on gut health.

3 Mar 2025

Lipid signatures could guide personalized treatment for colorectal cancer

Colorectal cancer, the second most common cause of cancer-related death, affects almost 2 million people worldwide every year.

26 Feb 2025

Microgreens outshine mature vegetables: Study finds higher antioxidants and bioactive compounds

Researchers analyzed six microgreens, revealing their diverse nutritional profiles, high antioxidant content, and potential to combat micronutrient deficiencies.

23 Feb 2025

Breast cancer risk and chemical exposure: New evidence points to triclosan as a key culprit

Researchers found that moderate triclosan exposure is significantly linked to increased breast cancer risk, particularly in younger, overweight, and White women, while other endocrine-disrupting chemicals showed mixed or no associations.

4 Feb 2025

Sex-specific mitochondrial marker deficiencies linked to early cognitive dysfunction in Alzheimer’s disease

Research reveals sex-specific free-carnitine deficiency in women with cognitive impairment, linking mitochondrial metabolism to Alzheimer's disease progression.

10 Jan 2025

Experts warn about counterfeit and illicit alcohol during the holiday season

Experts from a renowned international brewing and distilling centre are warning people to watch out for counterfeit and illicit alcohol - spirits - whether they're travelling abroad over the festive season or celebrating at home.

23 Dec 2024

Pharmacokinetics and chemical composition of Shenqi Fuzheng

Shenqi Fuzheng (SQ) is a widely used Chinese medicine formula known for its immune-enhancing and Qi-supplementing properties.

23 Dec 2024

Insulin degradation uncovered as a new driver of resistance

Researchers reveal insulin resistance may be driven by insulin degradation during transit in the bloodstream, challenging the belief that cell defects are the primary cause.

22 Dec 2024

Breastfeeding after COVID-19 vaccination is safe, with minimal changes to milk composition

This study reveals how SARS-CoV-2 infection significantly alters human milk composition, while COVID-19 vaccination causes minimal, transient changes, underscoring the safety of breastfeeding during vaccination.

19 Dec 2024

Lipid imbalances hold the key to chronic inflammation in colon cancer

Scientists uncover how disrupted lipid metabolism fuels chronic inflammation in colorectal cancer, offering insights into new therapeutic strategies targeting pro-inflammatory and pro-resolving lipid imbalances.

12 Dec 2024