Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

An article published in NPJ Aging, a Springer Nature journal, reveals that natural production of auto-antibodies increases with age and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19.

12 Sep 2023

Researchers develop a wearable bioelectronic system for wound healing treatment delivery

Researchers presented a wearable bioelectronic system to deliver therapeutic agents associated with wound healing.

12 Sep 2023

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers found that short-term intensive fasting enhances the immune function of red blood cells, including their ability to combat SARS-CoV-2, without affecting their oxygen-carrying capacity. The study reveals that this fasting regimen popular in Asia could offer a multifaceted benefit by amplifying the body's defenses without compromising essential functions.

4 Sep 2023

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, "Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging."

31 Aug 2023

Lung cells can be trained to counteract inflammation

Inflammation is a standard part of our bodies' immune system response. But sometimes this response becomes hyperactivated in our lungs, causing inflammation to continue unchecked, which can be fatal. Many deaths from COVID-19 have been due to excessive inflammation, which results in acute lung injury.

24 Aug 2023

New insights into the pathogenic mechanisms of SLC29A3 disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

22 Aug 2023

Study reveals anti-inflammatory power of Black Soldier Fly Larvae oil in inflammatory-related conditions

New study reveals the anti-inflammatory power of Black Soldier Fly Larvae (BSFL) oil, shedding light on its potential to alleviate inflammation in conditions like ulcerative colitis.

21 Aug 2023

Severe COVID-19 may cause long-term changes to innate immune system

Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

18 Aug 2023

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Researchers developed a one-step method to engineer multifunctional M1 phenotype macrophages.

14 Aug 2023

Tiny particles made from red blood cells may treat atherosclerosis and other diseases

Atherosclerosis is a disease in which fat, cholesterol, and other substances build up inside artery walls. This can lead to plaque formation, which can block arteries and cause heart attacks and strokes.

10 Aug 2023

Spatially-resolved macrophage phenotyping in liver disease-related research

This review manuscript highlights the relevance of spatially-resolved macrophage phenotyping in liver disease-related research.

8 Aug 2023

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

Study reports the first protein-based diagnostic signature to discriminate MIS-C from Kawasaki Disease and other common infections

Researchers explore the distinguishing features of MIS-C as compared to other inflammatory-infectious syndromes in children.

4 Aug 2023

Macrophage News and Research

Further Reading

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

Researchers develop a wearable bioelectronic system for wound healing treatment delivery

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

Lung cells can be trained to counteract inflammation

New insights into the pathogenic mechanisms of SLC29A3 disorders

Study reveals anti-inflammatory power of Black Soldier Fly Larvae oil in inflammatory-related conditions

Severe COVID-19 may cause long-term changes to innate immune system

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Tiny particles made from red blood cells may treat atherosclerosis and other diseases

Spatially-resolved macrophage phenotyping in liver disease-related research

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Study reports the first protein-based diagnostic signature to discriminate MIS-C from Kawasaki Disease and other common infections

Expression of two key genes influences cancer progression

Genetic variant may explain why some people of African ancestry have lower HIV viral loads

RNF41 protein could be a new therapeutic target against cirrhosis and liver inflammation

Researchers discover a protein that plays critical roles in alerting the body to a bacterial infection

Secretion of more immune protein protects females against obesity

The role of airway epithelium: insights into asthma and COPD pathogenesis

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