Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Using blood proteins to make living brains transparent

Making a living brain transparent and watching its neurons fire without disturbing their function-sounds like science fiction, doesn't it? Yet the solution may already exist within our own bodies.

13 Mar 2026

Viagra ingredient improves symptoms in patients with Leigh syndrome

Sildenafil – an active ingredient also marketed under the name of Viagra – improves symptoms in patients with Leigh syndrome.

11 Mar 2026

Alginate-enhanced gel improves organoid development

Miniature organs grown in the lab can organize themselves into complex shapes. But they never do it the same way twice, which makes it hard to use these so-called 'organoids' to study disease.

10 Mar 2026

Wnt signaling in fibroblasts drives gastric cancer metastasis to the liver

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to distant organs.

6 Mar 2026

Study aims to understand molecular origins of CTNNB1 neurodevelopmental syndrome

On the occasion of Rare Disease Day, the Biofisika Institute (CSIC, EHU) presents the progress of a project aimed at understanding the molecular origin of CTNNB1 neurodevelopmental syndrome, a rare disease caused by mutations in the beta-catenin protein.

27 Feb 2026

Brain organoids show goal-directed learning in control task

Imagine balancing a ruler vertically in the palm of your hand: you have to constantly pay attention to the angle of the ruler and make many small adjustments to make sure it doesn't fall over. It takes practice to get good at this.

19 Feb 2026

Cyborg transplants may advance cell-based therapies for diabetes

A new electronic implant system can help lab‑grown pancreatic cells mature and function properly, potentially providing a basis for novel, cell-based therapies for diabetes.

19 Feb 2026

Axol Bioscience acquires ophthalmology business from Newcells Biotech

Axol Bioscience Ltd. (Axol), a leading provider of induced pluripotent stem cell (iPSC) technologies for drug discovery and research, today announced that it has acquired the ophthalmology business of Newcells Biotech (Newcells), a leading drug discovery partner specializing in the development of in vitro models and bespoke assay services.

18 Feb 2026

Study identifies distinctive feature of tissues from young patients with colorectal cancer

A study co-led by University of Texas at Dallas bioengineers identified a distinctive feature of tissues from young patients diagnosed with colorectal cancer, a disease that typically affects older patients.

17 Feb 2026

Vitamin A and thyroid hormones in the retina shape fetal vision

Humans develop sharp vision during early fetal development thanks to an interplay between a vitamin A derivative and thyroid hormones in the retina, Johns Hopkins University scientists have found.

13 Feb 2026

Northwestern scientists develop advanced organoid model for human spinal cord injury

Northwestern University scientists have developed the most advanced organoid model for human spinal cord injury to date.

11 Feb 2026

Brain immune cells regulate new neuron formation in adults

Breakthrough research from the University of Cincinnati College of Medicine is revealing how immune cells in the adult brain can regulate the generation of new neurons.

9 Feb 2026

Revvity unveils new high-impact discovery platforms and showcases recent innovations at SLAS2026

Revvity, Inc. announced the launch of multiple new discovery platforms and technologies at SLAS2026, which are designed to accelerate high-throughput drug discovery workflows.

5 Feb 2026

Early pregnancy reshapes breast aging and lowers cancer risk

A new study by cell biologists at the University of California, Santa Cruz, suggests that an early first pregnancy may protect against breast cancer decades later by preventing age-related changes in breast cells that are linked to tumor formation.

3 Feb 2026

Advancing brain microphysiological systems for in vitro neurotoxicity and cognitive function testing

Brain microphysiological systems are reshaping in vitro neurotoxicity testing through functional validation and advanced disease modeling.

From Yokogawa Life Science 3 Feb 2026

iXCells Biotechnologies and Rosebud Biosciences partner to advance organoid-based models for rare diseases

iXCells Biotechnologies ("iXCells"), a leading provider of human cell-based solutions and custom iPSC services, and Rosebud Biosciences, an innovator in organoid development and complex 3D biology, today announced a partnership to develop a personalized, human-based approach for predicting drug safety and informing translational decision-making in rare diseases.

27 Jan 2026

Brain organoids reveal glioblastoma's secrets and therapy resistance

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

27 Jan 2026