Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Study dispels the hypothesis that metformin could help exercising seniors gain more muscle mass

A clinical trial initiated by University of Kentucky researchers argues against the hypothesis that the diabetes drug metformin could help exercising seniors gain more muscle mass. The double-blind trial, conducted at the University of Kentucky and University of Alabama at Birmingham, found that older adults who took metformin while performing rigorous resistance exercise training had smaller gains in muscle mass than the placebo group.

22 Oct 2019

Study blunts hopes that diabetes drug could help exercising seniors gain more muscle mass

A new clinical trial dispels the hypothesis that the diabetes drug metformin could help exercising seniors gain more muscle mass.

22 Oct 2019

New treatment shows promise to reverse celiac disease

Results of a new phase 2 clinical trial using technology developed at Northwestern Medicine show it is possible to induce immune tolerance to gluten in individuals with celiac disease. The findings may pave the way for treated celiac patients to eventually tolerate gluten in their diet.

22 Oct 2019

Patients with diabetes may have worse lung infections

People with diabetes are at a higher risk of various complications, including worse respiratory diseases. One of the most dreaded lung diseases is the Middle East respiratory syndrome coronavirus (MERS-CoV), which emerged in Saudi Arabia in 2012.

21 Oct 2019

New drug treats inflammation related to inherited heart disease in young athletes

When young athletes experiences sudden cardiac death as they run down the playing field, it's usually due to arrhythmogenic cardiomyopathy, an inherited heart disease.

From Johns Hopkins Medicine 17 Oct 2019

Study shows microbleeds after head injury signal danger to brain function

A new study published in the journal Brain shows that microbleeds appearing after trauma can cause patients with head injury to have poor outcomes. Advanced imaging techniques were used to establish this finding.

14 Oct 2019

Coffee beans show promise in fighting inflammation, insulin resistance

Coffee has long been proven to provide many health benefits. Aside from its ability to keep us awake throughout the day, it is packed with antioxidants that ward off free radicals.

14 Oct 2019

Extracts from coffee bean skins reduce fat-induced inflammation, insulin resistance in mouse cells

When coffee beans are processed and roasted the husk and silverskin of the bean are removed and unused, and often are left behind in fields by coffee producers.

11 Oct 2019

Cell discovery could help fight against liver disease

Scientists have identified new sub-types of cells that, when they interact, accelerate the scarring process in diseased livers.

9 Oct 2019

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Multiple sclerosis, an autoimmune disorder, is known to be driven by "helper" T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord. A new study from Boston Children's Hospital pinpoints the specific subgroup of helper T cells that cause MS, as well as a protein on their surface, called CXCR6, that marks them.

4 Oct 2019

Study explores how macrophage specialization gets disrupted by liver disease

Every tissue in the human body has an immune cell in it called a macrophage. Macrophages play important roles in the immune system's initial response to bacteria, viruses and wounds.

4 Oct 2019

Findings could open up new research avenues into how heme tolerance occurs in humans

Most people have some idea of how important iron is to their health, but Iqbal Hamza, professor in Animal and Avian Sciences, has made his seventeen-year career at the University of Maryland all about the study of iron and heme trafficking and regulation in the body.

1 Oct 2019

Texas Biomed researchers zeroing in on new way to target TB with $2.8 million NIH grant

Researchers at Texas Biomedical Research Institute are zeroing in on a new way to target tuberculosis infection. The National Institutes of Health has awarded a four-year, $2.8 million grant for scientists to study the role of lung macrophages (immune cells) in metabolic and inflammation responses to TB.

1 Oct 2019

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

An international, multicenter phase II clinical trial is evaluating the efficacy and safety of mavrilimumab co-administered with a 26-week corticosteroid taper in patients with giant cell arteritis.

26 Sep 2019

Dormant HIV reservoirs could be killed with RNA switch

Researchers from the University of California San Diego School of Medicine have found cellular triggers within the immune cells that could be controlled in order to kill dormant HIV-1 reservoirs in individuals with HIV-1.

25 Sep 2019

Acne may be a natural, transient inflammatory state when facial skin is exposed to microbes

Adolescent acne does not always result in a pathological condition; rather, it may be a natural, transient inflammatory state occurring when the maturing facial skin is exposed to new microbes and enhanced production of an oily substance called sebum, according to a Forum article published on September 26 in the journal Trends in Immunology.

25 Sep 2019

Researchers identify key switch that eliminates dormant HIV reservoirs

Using genetic sequencing, University of California San Diego School of Medicine researchers have identified a principal cellular player controlling HIV reproduction in immune cells which, when turned off or deleted, eliminates dormant HIV reservoirs.

24 Sep 2019

Vaping destroys lining and immune cells in the lung, says study

Now, a new study shows that the vapor emitted by the electronic cigarettes is vaping is linked to much higher rates of cell death among airway epithelial cells – more than double, from about 9% in controls to 17-20% in the exposed cells.

24 Sep 2019

Alzheimer’s drug an interesting candidate for the treatment of parasitic Chagas disease

Researchers have discovered that an Alzheimer's drug could serve as a starting point in treating Chagas disease.

20 Sep 2019

Stem cells with 'dual identity' associated with loss of smell from inflammation in chronic sinusitis

In experiments with mice and human tissue samples, Johns Hopkins Medicine researchers report evidence that neuronal stem cells in the part of the nose responsible for the sense of smell transform themselves to perpetuate the long-term inflammation in chronic sinusitis.

19 Sep 2019

Macrophage News and Research

Further Reading

Study dispels the hypothesis that metformin could help exercising seniors gain more muscle mass

Study blunts hopes that diabetes drug could help exercising seniors gain more muscle mass

New treatment shows promise to reverse celiac disease

Patients with diabetes may have worse lung infections

New drug treats inflammation related to inherited heart disease in young athletes

Study shows microbleeds after head injury signal danger to brain function

Coffee beans show promise in fighting inflammation, insulin resistance

Extracts from coffee bean skins reduce fat-induced inflammation, insulin resistance in mouse cells

Cell discovery could help fight against liver disease

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Study explores how macrophage specialization gets disrupted by liver disease

Findings could open up new research avenues into how heme tolerance occurs in humans

Texas Biomed researchers zeroing in on new way to target TB with $2.8 million NIH grant

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

Dormant HIV reservoirs could be killed with RNA switch

Acne may be a natural, transient inflammatory state when facial skin is exposed to microbes

Researchers identify key switch that eliminates dormant HIV reservoirs

Vaping destroys lining and immune cells in the lung, says study

Alzheimer’s drug an interesting candidate for the treatment of parasitic Chagas disease

Stem cells with 'dual identity' associated with loss of smell from inflammation in chronic sinusitis

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