Enzyme News and Research

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Biomarkers of food intake: The key to precision nutrition

Researchers examine the potential utility of biomarkers of food intake on objective and accurate dietary assessments.

5 Jul 2024

New study reveals how RNA polymerase opens the transcription bubble in real time

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA.

3 Jul 2024

Repurposing cancer drug to prevent organ damage in infectious diseases

Twelve years ago, cancer researchers at University of California San Diego identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue.

3 Jul 2024

Machine learning revolutionizes cardiac studies in fruit flies

Drosophila - commonly known as fruit flies - are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy.

3 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

Key differences in RNA editing found between postmortem and living brain

Researchers examined the adenosine-to-inosine (A-to-I) nucleoside editing of postmortem and live prefrontal cortical tissues.

3 Jul 2024

Decoding the significance of subnormal liver enzyme activity

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

3 Jul 2024

Pharmacogenomics: A pathway to personalized treatment in prostate cancer

Prostate cancer (PC) stands as the second leading cause of death among American men, with about 1 in 8 men diagnosed during their lifetime.

2 Jul 2024

Study hints at a promising approach for treating wet age-related macular degeneration

A new study in mice hints at the promise of an eventual alternative treatment option for the "wet" version of age-related macular degeneration (AMD).

2 Jul 2024

Study provides new clues in the understanding of how antibiotic resistance spreads

A study at Umeå University, Sweden, provides new clues in the understanding of how antibiotic resistance spreads.

1 Jul 2024

Pristimerin induces apoptosis in non-small cell lung cancer by targeting thioredoxin reductase

Announcing a new publication for Acta Materia Medica journal. Elevated cellular oxidative stress is a common marker of cancer cell dysregulation caused by malignant transformation.

30 Jun 2024

Study finds women lost more of their body weight on average with semaglutide than men

Researchers performed a secondary analysis of the semaglutide treatment effect in people with obesity and heart failure with a preserved left ventricular ejection fraction program that included individuals with diabetes mellitus, stratified by biological sex.

26 Jun 2024

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine.

25 Jun 2024

Chimpanzees seek out tree bark and ferns with medicinal benefits, researchers discover

Researchers investigated the behavioral and pharmacological effects of self-medicative plants in the diets of Budongo chimpanzees.

25 Jun 2024

New enzyme targets hold promise for cancer therapies

Researchers at Baylor College of Medicine and collaborating institutions have uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets, expanding the breadth of possibilities for treating this disease. Using a comprehensive approach that included integrating proteomics, genomics and epigenomics data from 10 cancer types, the team identified protein and small protein or peptide targets in cancer tissues and validated many of them experimentally as promising candidates for therapeutic strategies. The study appeared in Cell.

25 Jun 2024

Study reveals early immune responses to SARS-CoV-2, offering insights for future COVID-19 treatments

Researchers analyzed early immune responses to SARS-CoV-2 using single-cell multi-omics, revealing key cellular states associated with different infection outcomes.

24 Jun 2024

New study reveals the therapeutic potential of ZED1227 in celiac disease

A recent study led by researchers at Tampere University investigated whether a transglutaminase 2 inhibitor has potential as a drug to treat celiac disease.

24 Jun 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

UCF researcher further explores nanotech to improve cancer and disease detection

Early discovery of debilitating diseases such as cancer or dementia is critical in determining treatment and saving lives.

21 Jun 2024

Breakthrough in enzyme communication could pave the way for new drugs

A mechanism that could help scientists harness enzymes for use in drug discovery has been discovered in a research breakthrough at the University of Birmingham.

20 Jun 2024

Enzyme News and Research

Biomarkers of food intake: The key to precision nutrition

New study reveals how RNA polymerase opens the transcription bubble in real time

Repurposing cancer drug to prevent organ damage in infectious diseases

Machine learning revolutionizes cardiac studies in fruit flies

White blood cell type identified as important contributor to inflammation in obesity

Key differences in RNA editing found between postmortem and living brain

Decoding the significance of subnormal liver enzyme activity

Pharmacogenomics: A pathway to personalized treatment in prostate cancer

Study hints at a promising approach for treating wet age-related macular degeneration

Study provides new clues in the understanding of how antibiotic resistance spreads

Pristimerin induces apoptosis in non-small cell lung cancer by targeting thioredoxin reductase

Study finds women lost more of their body weight on average with semaglutide than men

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

Chimpanzees seek out tree bark and ferns with medicinal benefits, researchers discover

New enzyme targets hold promise for cancer therapies

Study reveals early immune responses to SARS-CoV-2, offering insights for future COVID-19 treatments

New study reveals the therapeutic potential of ZED1227 in celiac disease

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

UCF researcher further explores nanotech to improve cancer and disease detection

Breakthrough in enzyme communication could pave the way for new drugs

Measuring Drug-Target Residence Times with Biochemical Assays eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo