B Cell News and Research

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ISSCR expresses concern over NIH decision on fetal tissue research funding

The International Society for Stem Cell Research (ISSCR), the largest professional organization of stem cell researchers from around the world, is concerned about a recent statement attributed to NIH that the agency will not renew research grants involving human fetal tissue (HFT), and that research with HFT is not conducted responsibly or transparently.

13 Sep 2025

Cryo-EM reveals how blood clotting proteins fit together to trigger clot formation

If you've ever accidentally sliced yourself on a broken glass or a piece of paper, you may have noticed that the bleeding can be hard to stop.

13 Sep 2025

Novel RNA target offers hope for improving outcomes in patients with chronic limb ischemia

Mark W. Feinberg, MD, cardiologist with the Mass General Brigham Heart and Vascular Institute and professor of medicine at Harvard Medical School, is the senior author of a paper published in the Journal of Clinical Investigation, "A smooth muscle cell lncRNA controls angiogenesis in chronic limb-threatening ischemia through miR-143-3p/HHIP signaling."

13 Sep 2025

Simple AI model matches dermatologist expertise in assessing squamous cell carcinoma

A simple AI model has been shown to perform on a par with experienced dermatologists when assessing the aggressiveness of a common form of skin cancer, squamous cell carcinoma. The research was headed by the University of Gothenburg.

13 Sep 2025

Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk

Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting exposure to smoke, may reduce the risk of this disease.

13 Sep 2025

Review highlights immunomodulatory and therapeutic effects of ginseng

Ginseng has long been used in traditional medicine to replenish Qi and address deficiency syndromes, often manifesting as fatigue and immune compromise.

13 Sep 2025

A universal solution emerges: Anti-linker antibodies simplify CAR-T detection and development

CAR-T cell therapy has demonstrated remarkable success in treating hematologic malignancies and is now expanding into solid tumors.

From Sino Biological Inc. 13 Sep 2025

Labman leads international project to develop AI-powered bioreactor platform for next-generation biologics

Labman is proud to be involved in a groundbreaking Canada-UK collaboration to revolutionize biopharmaceutical manufacturing using cutting-edge automation, AI, and real-time process control.

From Labman 13 Sep 2025

European study identifies risk factors and outcomes in fulminant myocarditis

A multicenter study coordinated by the University Hospital Bonn (UKB) involving 26 European centers provides new insights into the course of the disease, prognosis assessment, and risk factors for severe myocarditis.

12 Sep 2025

Repurposed diabetes drugs boost CAR T therapy effectiveness in bladder cancer

Urothelial carcinoma (UC) is the second most common genitourinary cancer, leading to over 16,000 deaths a year in the United States. Despite recent advances, the 5-year survival rate for metastatic UC remains around five to ten percent.

12 Sep 2025

Bacteria use density switch to balance virulence and growth

Pathogens are becoming more and more resistant to antibiotics. With the goal of developing new therapeutic approaches to treat bacterial infections more effectively in the future, researchers at the Karlsruhe Institute of Technology (KIT) and the Max Planck Institute in Marburg investigated the plague-related bacterium Yersinia enterocolitica.

12 Sep 2025

Abnormal protein activity found to promote cell migration and spread of glioblastoma

Ever wondered how the different cells in our body communicate with each other to fulfill their different roles-be it cells repairing a tissue injury or immune cells moving towards an invading pathogen (microorganisms that causes disease) to engulf it?

11 Sep 2025

Study identifies C1orf122 as prognostic marker in liver cancer

Primary liver cancer is the third leading cause of cancer-related deaths, of which hepatocellular carcinoma (HCC) accounts for approximately 90% of all liver cancer cases.

11 Sep 2025

Blocking immune brake protein boosts defense against Aspergillus fumigatus

People are exposed to millions of fungal spores every day, even potentially harmful ones like those from Aspergillus fumigatus.

11 Sep 2025

Object recognition shapes spatial awareness in the brain

We take our understanding of where we are for granted, until we lose it. When we get lost in nature or a new city, our eyes and brains kick into gear, seeking familiar objects that tell us where we are.

11 Sep 2025

Citrus flavonoid hesperidin lowers oxidative damage in cell experiments

Researchers tested hesperidin extracted from citrus peels and found it reduced inflammatory cytokines and oxidative stress markers in cultured immune cells. The findings highlight hesperidin’s strong in vitro anti-inflammatory and antioxidant potential, warranting further in vivo research.

11 Sep 2025

Scientists uncover brain circuit that turns cravings into eating behavior

Researchers found that the bed nucleus of the stria terminalis integrates pleasure signals from central amygdala prodynorphin neurons and hunger signals from agouti-related peptide neurons to drive consumption. Manipulating this bed nucleus of the stria terminalis circuit bidirectionally altered food intake and body weight in mice.

11 Sep 2025

BU professor wins RF1 $3.2M grant for age-related neuropathology research

Tara Moore, PhD, professor of anatomy & neurobiology at Boston University Chobanian & Avedisian School of Medicine, has been awarded a five-year, RF1 $3.2M grant from the NIH's National Institute of Aging for her project "Extracellular vesicle treatment and age-related neuropathology in non-human primates."

11 Sep 2025

Study challenges conventional thinking about the onset of Type 2 diabetes

A study from The University of Texas at San Antonio Health Science Center indicates that changes in the body that lead to Type 2 diabetes occur long before current diagnostic thresholds for prediabetes are met.

11 Sep 2025

Weill Cornell Medicine receives $3.4 million NIH grant to study type 1 diabetes development

Weill Cornell Medicine has received a four-year, $3.4 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, for a study of the details and dynamics of the autoimmune process that causes type 1 diabetes.

11 Sep 2025

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B Cell News and Research

ISSCR expresses concern over NIH decision on fetal tissue research funding

Cryo-EM reveals how blood clotting proteins fit together to trigger clot formation

Novel RNA target offers hope for improving outcomes in patients with chronic limb ischemia

Simple AI model matches dermatologist expertise in assessing squamous cell carcinoma

Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk

Review highlights immunomodulatory and therapeutic effects of ginseng

A universal solution emerges: Anti-linker antibodies simplify CAR-T detection and development

Labman leads international project to develop AI-powered bioreactor platform for next-generation biologics

European study identifies risk factors and outcomes in fulminant myocarditis

Repurposed diabetes drugs boost CAR T therapy effectiveness in bladder cancer

Bacteria use density switch to balance virulence and growth

Abnormal protein activity found to promote cell migration and spread of glioblastoma

Study identifies C1orf122 as prognostic marker in liver cancer

Blocking immune brake protein boosts defense against Aspergillus fumigatus

Object recognition shapes spatial awareness in the brain

Citrus flavonoid hesperidin lowers oxidative damage in cell experiments

Scientists uncover brain circuit that turns cravings into eating behavior

BU professor wins RF1 $3.2M grant for age-related neuropathology research

Study challenges conventional thinking about the onset of Type 2 diabetes

Weill Cornell Medicine receives $3.4 million NIH grant to study type 1 diabetes development

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