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Researchers unravel the biology of how obesity promotes triple-negative breast cancer

Smoking has long been the biggest cause of cancer in the United States, but obesity, now the second leading cause, has been gaining ground.

7 May 2019

Scientists discover biological barrier that keeps cancer at bay

Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function.

6 May 2019

Scientists unravel mechanism of action of antitumor drug used to treat glioblastoma

Glioblastoma is an incurable type of brain tumor that is frequently associated with mutations in the epidermal growth factor receptor.

3 May 2019

Cannabis, Alcohol and the Epigenome

With the legalization of cannabis in many US states, we explore the epigenetic effects of cannabis, cannabis-derived products, and alcohol.

29 Apr 2019

Circadian rhythm plays a part in weight loss

Weight watchers worldwide need to not only be careful about what to eat but also about the timing of the food intake finds a new study.

26 Apr 2019

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

Rutgers researchers identify new factor essential for maintaining stem cells in the brain and gut

The organs in our bodies house stem cells that are necessary to regenerate cells when they become damaged, diseased or too old to function.

17 Apr 2019

FDA approves new treatment for adults with metastatic bladder cancer

The U.S. Food and Drug Administration today granted accelerated approval to Balversa (erdafitinib), a treatment for adult patients with locally advanced or metastatic bladder cancer that has a type of susceptible genetic alteration known as FGFR3 or FGFR2, and that has progressed during or following prior platinum-containing chemotherapy.

12 Apr 2019

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Biomolecular researcher Navin Varadarajan has published in Arthritis & Rheumatology journal a first-of-its-kind study - a comprehensive profile of B cells in rheumatoid arthritis.

12 Apr 2019

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre, have published in Cancer Cell the results of a study that shows full regression of advanced pancreatic ductal adenocarcinoma upon combined inhibition of the epidermal growth factor receptor and c-RAF kinase.

12 Apr 2019

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

A new molecule -EPB-53-, could help fight type 2 diabetes and the non-alcoholic fatty liver disease, according to a new study led by the team of Manuel Vázquez-Carrera, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the University of Barcelona, and the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Center.

10 Apr 2019

Celltrion and iProgen Biotech announce partnership for development of novel ADCs

On April 8, Celltrion and the Canada-based iProgen Biotech Inc. announced to agree to partner for the development of novel ADCs against validated antibody targets, including HER2 and CD20.

8 Apr 2019

FDA extends indication of metastatic breast cancer treatment to include male patients

The U.S. Food and Drug Administration today is extending the indication of Ibrance (palbociclib) capsules in combination with specific endocrine therapies for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in male patients.

5 Apr 2019

UCR study: Surgery associated with higher survival of patients with HER2-positive stage 4 breast cancer

A student at the University of California, Riverside, presented research results at the annual meeting of the American Association for Cancer Research, or AACR, in Atlanta showing that surgery is associated with higher survival rates for patients with HER2-positive stage 4 breast cancer compared with those who did not undergo surgery.

3 Apr 2019

NHS to roll-out new test for potentially lethal pre-eclampsia

NHS England will be rolling out a new blood test for pregnant women to check for pre-eclampsia, a common and potentially life-threatening condition.

2 Apr 2019

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

A new study led by Massachusetts General Hospital (MGH) investigators finds that radiation therapy may increase the uptake of therapeutic nanoparticles by glioblastomas, raising the possibility of using both growth-factor-targeted and immune-system-based therapies against the deadly brain tumor.

28 Mar 2019

Inherited form of rickets improves more with new injectable medicine than conventional therapy

Burosumab, a new injectable medicine to treat X-linked hypophosphatemia (XLH), an inherited form of rickets, demonstrates superior improvements in rickets and other outcomes compared with conventional therapy in an international, phase 3 clinical trial in children.

25 Mar 2019

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

22 Mar 2019

Gene medication shows promise to treat spinal cord injuries

The two-gene medication has been proven to recover motor functions in rats. After several months of treatment, rodents were able to use previously paralyzed limbs. Researchers at Kazan Federal University are now seeking pre-clinical trial investment.

18 Mar 2019

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

Exposure to potentially harmful chemicals is a reality of life. Our ancestors, faced with naturally occurring toxins, evolved mechanisms to detoxify and expel damaging substances.

15 Mar 2019

Growth Factor News and Research

Researchers unravel the biology of how obesity promotes triple-negative breast cancer

Scientists discover biological barrier that keeps cancer at bay

Scientists unravel mechanism of action of antitumor drug used to treat glioblastoma

Cannabis, Alcohol and the Epigenome

Circadian rhythm plays a part in weight loss

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

Rutgers researchers identify new factor essential for maintaining stem cells in the brain and gut

FDA approves new treatment for adults with metastatic bladder cancer

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

Celltrion and iProgen Biotech announce partnership for development of novel ADCs

FDA extends indication of metastatic breast cancer treatment to include male patients

UCR study: Surgery associated with higher survival of patients with HER2-positive stage 4 breast cancer

NHS to roll-out new test for potentially lethal pre-eclampsia

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

Inherited form of rickets improves more with new injectable medicine than conventional therapy

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Gene medication shows promise to treat spinal cord injuries

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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