Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Whole body vibration adjusts the microbiome and immune cells to deter inflammation in diabetes

In the face of diabetes, a common condition in which glucose and levels of destructive inflammation soar, whole body vibration appears to improve how well our body uses glucose as an energy source and adjust our microbiome and immune cells to deter inflammation, investigators report.

5 Aug 2019

Harnessing anti-inflammatory function of macrophages holds great potential for treating diseases

Researchers at the University of Illinois at Chicago have identified a molecular switch that causes immune cells called macrophages to clean up cellular debris caused by infections instead of contributing to inflammation and tissue injury.

31 Jul 2019

Randox unveils innovative test for risk assessment of cardiovascular disease

Global diagnostics company Randox Laboratories has unveiled an innovative new test for the risk assessment of cardiovascular disease at this year's AACC Clinical Lab Expo in Anaheim, California.

26 Jul 2019

Defective immune signals could underlie some types of fatal heart disease

Researchers have come up with exciting evidence that confirms the role of abnormal immune signaling in myocarditis.

25 Jul 2019

Extracellular vesical microRNAs from fat cells can disrupt disposal of cholesterol

A multi-institutional team led by research faculty at Children's National in Washington, D.C., finds that extracellular vesicles (EVs) derived from kids' fat can play a pivotal role in ratcheting up risk for atherosclerotic cardiovascular disease well before any worrisome symptoms become visible.

24 Jul 2019

New organic molecule could become potent weapon in the fight against antibiotic resistance

An organic molecule composed of simple sugars could become a potent weapon in the fight against rising antibiotic resistance, according to EU-funded researchers who have developed a novel, targeted drug-delivery technique to treat deadly tuberculosis and other lethal pathogens.

21 Jul 2019

Disruption of immune cell behavior may spur heart disease, heart failure

On an ice hockey team, the players all start off with identical uniforms, skates and a stick. But if you take one of them, add padding, a glove, and a mask; and switch the stick to one with a larger blade, then you get a goalie.

From Johns Hopkins Medicine 19 Jul 2019

Study reveals how aggressive prostate cancer metastasizes by evading the immune system

Researchers at The University of Texas MD Anderson Cancer Center have discovered how an aggressive form of prostate cancer called double-negative prostate cancer (DNPC) metastasizes by evading the the immune system.

18 Jul 2019

UMass Amherst scientist receives $792,000 grant to advance cancer immunotherapy research

Biomedical engineer Ashish Kulkarni, assistant professor of chemical engineering at the University of Massachusetts Amherst, has been awarded a four-year, $792,000 grant from the American Cancer Society to advance his interdisciplinary lab's promising cancer immunotherapy research.

16 Jul 2019

Researchers identify new subtypes of motor neurons and microglia present in ALS patients

Amyotrophic lateral sclerosis, or ALS, is an adult-onset neurodegenerative disease that causes paralysis and ultimately death when the nerves enervating the lungs cease to carry the signals needed for breathing.

16 Jul 2019

How cell-free DNA can be targeted to prevent spread of tumors

Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes.

12 Jul 2019

Schwann cells induce self-repair of damaged nerves

Researchers from Gutenberg University Mainz (JGU) and at the Swiss University of Fribourg have now found that the Schwann cells and axons may be behind this regeneration process.

11 Jul 2019

Comprehensive cell atlas of the human liver

The liver is one of the largest and most versatile organs of the human body. It turns sugars, proteins, and fats from our food into substances useful for the body and releases them to the cells.

11 Jul 2019

Study sheds light on complex caspase-1-induced cell death mechanisms

Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program.

5 Jul 2019

Findings suggest new ways to help the immune system fight pancreatic cancer

Findings published today in the journal Science Translational Medicine suggest that a type of white blood cell called tumor associated macrophages that have been deceived by pancreatic cancer cells into not attacking them can be "re-programmed" by a specially designed molecule that activates a protein found on their surfaces.

4 Jul 2019

Non-pathogenic bacteria engineered as Trojan Horse to treat tumors from within

The emerging field of synthetic biology-designing new biological components and systems-is revolutionizing medicine.

4 Jul 2019

New resistance mechanism that prevent formation of blood vessels

Researchers at IDIBELL-ICO describe a new resistance mechanism to therapies that prevent the formation of blood vessels

3 Jul 2019

Large doses of traditional chemotherapy drug spur immune system attack on cancer cells

More than 60 years ago, British physician Denis Parsons Burkitt and his associates achieved one of the signal successes in cancer medicine when they cured children in sub-Saharan Africa with a form of lymphoma by treating them with high doses of the chemotherapy drug cyclophosphamide.

2 Jul 2019

Pharmaceutical products made of solid gold

Over the past twenty years, the use of nanoparticles in medicine has steadily increased. However, their safety and effect on the human immune system remains an important concern.

28 Jun 2019

Scientists use advanced imaging to track brain tumor 'turncoats'

Glioblastomas, the deadliest type of brain tumor in adults, attract "turncoats." These are macrophages, a type of immune cell, which promote tumor progression and mask tumors from the immune system's scrutiny.

26 Jun 2019