Spectroscopy News and Research

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Spectroscopy is the study of the interaction between radiation (electromagnetic radiation, or light, as well as particle radiation) and matter.

Pittcon 2015: Bruker introduces InsightMR software for on-line NMR analysis of chemical processes

Bruker is launching InsightMR software for on-line NMR analysis of chemical processes at Pittcon 2015. For the first time, a software platform enables the adjustment of experimental parameters based on real time data during the analysis of chemical processes by NMR spectroscopy.

From Bruker BioSpin Division 15 Mar 2016

Bruker expands capabilities of NMR-based Assure-RMS solution with launch of Chemometrics Module

Bruker Corporation introduces the Chemometrics Module, further expanding the capabilities of its proven Assure-RMS solution. Fully automated, quantitative and qualitative Nuclear Magnetic Resonance (NMR) analysis enables material screening in the polymer, pharmaceutical and dietary supplement industries.

From Bruker BioSpin Division 15 Mar 2016

Bruker showcases innovative NMR solutions for pharmaceutical industry at ENC 2015

At the 56th Experimental Nuclear Magnetic Resonance Conference, Bruker this week is show-casing several innovative drug discovery, drug development and process control solutions for small molecule NMR characterization in the pharmaceutical industry.

From Bruker BioSpin Division 15 Mar 2016

Scientists sort out mechanism of Alzheimer's disease development

A group of the Lomonosov Moscow State University scientists, together with their colleagues from the Institute of Molecular Biology, Russian Academy of Sciences and the King's College London, succeeded in sorting out the mechanism of Alzheimer's disease development and possibly distinguished its key trigger.

11 Mar 2016

Pittcon 2016: Bruker showcases new products and analytical solutions

This week at Pittcon 2016, Bruker is showcasing new products and analytical solutions for core Applied & Pharma markets, for our Nanoanalysis, Microscopy & Advanced Materials Research markets, as well as new after-market services and life-cycle support solutions for our customers.

From Bruker BioSpin Division 8 Mar 2016

First atomic-scale view of interaction between HIV capsid and host protein cyclophilin A

A new study offers the first atomic-scale view of an interaction between the HIV capsid - the protein coat that shepherds HIV into the nucleus of human cells - and a host protein known as cyclophilin A. This interaction is key to HIV infection, researchers say.

7 Mar 2016

Renishaw inVia to support development of nanomolecular probes in Kircher Laboratory at Memorial Sloan Kettering

The Kircher laboratory at Memorial Sloan Kettering is developing novel nanoprobes for molecular imaging, image-guided therapy and theranostics.

4 Mar 2016

Unlocking H5N1 virus replication: an interview with Martin Blackledge

We were able to show that one small domain of the polymerase, the part that is essential for entry of a piece of the polymerase into the cell nucleus, changes its conformation to allow it to interact with the transporter protein than takes it into the nucleus.

3 Mar 2016

Advances in the field of MPI: an interview with Professor Kannan Krishnan

In around 2004, there was a Phillips paper that discussed a new imaging technique called MPI. At that time, I had an eager, promising graduate student named Matt Ferguson who wanted a project, so I asked him to take a look.

From Bruker BioSpin Division 1 Mar 2016

Light reflectance spectroscopy may lead to real-time tissue analysis during prostate cancer surgery

Researchers at UT Southwestern Medical Center have determined that light reflectance spectroscopy can differentiate between malignant and benign prostate tissue with 85 percent accuracy, a finding that may lead to real-time tissue analysis during prostate cancer surgery.

27 Feb 2016

Unlocking intrinsically disordered proteins: an interview with Peter Wright

I'm a professor in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute. I have been performing NMR research on proteins for nearly 40 years.

From Bruker BioSpin Division 11 Feb 2016

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

A first-ever interlaboratory study of four versions of a therapeutic protein drug—all manufactured from living cells—reports that an established analytical tool akin to magnetic resonance imaging reliably assessed the atomic structures of the biologically similar products, yielding the equivalent of a fingerprint for each.

10 Feb 2016

Study finding could shed light on molecular mechanisms underlying Huntington's disease

Researchers at the University of Pittsburgh School of Medicine have shown that the core of the protein clumps found in the brains of people with Huntington's disease have a distinctive structure, a finding that could shed light on the molecular mechanisms underlying the neurodegenerative disorder.

4 Feb 2016

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

Single fluorescent molecules provide a local nanometer-sized probe of complex systems. We can measure the motion of the single molecule, use them to achieve imaging on a scale down to 20 nanometers, or we can infer aspects of the behaviour of the object under study by the details of the light that is emitted.

From Pittcon 26 Jan 2016

WASF3 protein appears to be solid target for reducing cancer metastasis

A protein that is constantly expressed by cancer cells and quiescent in healthy ones appears to be a solid target for reducing cancer's ability to spread, scientists report.

19 Jan 2016

New study shows neurocognitive benefits of stand-height desks in classrooms

Do students think best when on their feet? A new study by the Texas A&M Health Science Center School of Public Health indicates they do.

18 Jan 2016

Determining Ectopeptidase Activity: An Interview with Professor Stephen Weber, University of Pittsburgh

The scope of the activity of neuropeptides is remarkably broad. For example, neuropeptides are involved in pain control, mood/depression/eating disorders, social and emotional behaviour, body weight, drug abuse, stress, reproduction, motor control, memory, and in maintaining neuronal health when they are stressed.

From Pittcon 14 Jan 2016

Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Lewy bodies had been considered to be a key element of pathogenesis for Parkinson's disease. Although structural analysis for Lewy bodies with an electron microscope had been performed, it had no secondary structural information of proteins, which is important for the development of drugs.

13 Jan 2016

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine.

13 Jan 2016

Laser-induced breakdown spectroscopy emerges as fast, cost-efficient method for biomass analysis

Laser-induced breakdown spectroscopy (LIBS) is emerging as a fast, cost-efficient method for identifying the total amount and specific compounds that comprise the inorganic component of biomass. Accurate and reliable analysis of these minerals, such as aluminum, calcium, iron, and silicon is essential, as this "ash" can cause problems when converting biomass to hydrocarbon biofuels, as described in a study published in Industrial Biotechnology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

12 Jan 2016

Spectroscopy News and Research

Further Reading

Pittcon 2015: Bruker introduces InsightMR software for on-line NMR analysis of chemical processes

Bruker expands capabilities of NMR-based Assure-RMS solution with launch of Chemometrics Module

Bruker showcases innovative NMR solutions for pharmaceutical industry at ENC 2015

Scientists sort out mechanism of Alzheimer's disease development

Pittcon 2016: Bruker showcases new products and analytical solutions

First atomic-scale view of interaction between HIV capsid and host protein cyclophilin A

Renishaw inVia to support development of nanomolecular probes in Kircher Laboratory at Memorial Sloan Kettering

Unlocking H5N1 virus replication: an interview with Martin Blackledge

Advances in the field of MPI: an interview with Professor Kannan Krishnan

Light reflectance spectroscopy may lead to real-time tissue analysis during prostate cancer surgery

Unlocking intrinsically disordered proteins: an interview with Peter Wright

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

Study finding could shed light on molecular mechanisms underlying Huntington's disease

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

WASF3 protein appears to be solid target for reducing cancer metastasis

New study shows neurocognitive benefits of stand-height desks in classrooms

Determining Ectopeptidase Activity: An Interview with Professor Stephen Weber, University of Pittsburgh

Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Laser-induced breakdown spectroscopy emerges as fast, cost-efficient method for biomass analysis

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