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Blood group associated with cardiovascular events in COVID-19 patients

An illuminating new study by scientists at Harvard Medical School, USA, describes the correlation of such conditions with the ABO blood group. The team's findings may help assess the risk of COVID-19 patients for such complications, promoting early diagnosis and underscoring potential needs for preventive and therapeutic care where possible.

21 Jan 2021

ACE2 and furin levels linked to inflammation in smokers with COVID-19

A new study reports the level of ACE2 and furin, two enzymes that are intimately linked to infection with SARS-CoV-2, the causative agent of COVID-19.

21 Jan 2021

Can cancer patients receive urgent care without risk of COVID-19?

A new study describes how a successful application of mitigation techniques to prevent COVID-19 transmission to cancer patients admitted to or attending a healthcare facility might look.

21 Jan 2021

Monocytes could be a key player in sarcoidosis pathogenesis, study shows

The cause of the inflammatory lung disease sarcoidosis is unknown.

21 Jan 2021

Yurts, igloos and pop-up domes: How safe is ‘outside’ restaurant dining this winter?

With the arrival of winter and the U.S. coronavirus outbreak in full swing, the restaurant industry — looking at losses of $235 billion in 2020 — is clinging to techniques for sustaining outdoor dining even through the cold and vagaries of a U.S. winter.

21 Jan 2021

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today.

20 Jan 2021

Busting myths on airborne transmission of SARS-CoV-2

The rapid spread of COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to significant research on the mechanisms of how the virus spreads, which is usually by airborne transmission.

20 Jan 2021

Potentially promising therapeutic combination for renal cell carcinoma uncovered

Renal cell carcinoma (RCC) is the most common form of cancer of the kidney. In 2018, there were an estimated 403,000 new cases of RCC and 175,000 deaths due to kidney cancer worldwide.

20 Jan 2021

Nearly one third of UK's hospitalized COVID-19 patients readmitted

In a recent medRxiv preprint paper, researchers from the UK discussed how they determined organ impairment rates post recovery from COVID-19-related hospitalization and compared the results with that in a control group.

20 Jan 2021

People with problems in the upper GI tract may be vulnerable to COVID-19 infection

No evidence so far indicates that food or drinks can transmit the virus that causes COVID-19, but new research at Washington University School of Medicine in St. Louis suggests that people with problems in the upper gastrointestinal (GI) tract may be vulnerable to infection after swallowing the virus.

20 Jan 2021

COVID-19 has transformed the world of vaccines

Researchers at GlaxoSmithKline (GSK) in Italy and Belgium say the coronavirus disease 2019 (COVID-19) pandemic is transforming the world of vaccinology by accelerating vaccine development and the availability of powerful technologies.

20 Jan 2021

South African SARS-CoV-2 variant escapes antibody neutralization

Researchers in South Africa have conducted a study showing that the novel 501Y.V2 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has emerged in the country is able to escape the neutralizing antibodies that are elicited by previously circulating strains of the virus.

20 Jan 2021

Mask-wearing together with social distancing has maximum impact on COVID-19, study finds

A recent study published in the journal The Lancet has revealed that self-reported use of face masks together with social distancing has a considerable impact on controlling the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the United States.

20 Jan 2021

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

A study published recently in the journal Viruses has identified a potent diuretic ethacrynic acid as an efficient inhibitor of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This drug can be potentially repurposed to treat coronavirus disease 2019 (COVID-19).

20 Jan 2021

How does SARS-CoV-2 infect brain cells?

Researchers from the University of California San Francisco, Gladstone Institutes in the USA, and The Aga Khan University in Pakistan investigated if human neural cells can be infected by SARS-CoV-2.

20 Jan 2021

California is overriding its limits on nurse workloads as covid surges

California’s telemetry nurses, who specialize in the electronic monitoring of critically ill patients, normally take care of four patients at once. But ever since the state relaxed California’s mandatory nurse-to-patient ratios in mid-December, Nerissa Black has had to keep track of six.

20 Jan 2021

Can metabolic biomarkers help clinicians stratify adverse outcome risk in COVID-19 patients?

A recent study describes the alterations in lipids and other parameters that define the state of dysfunctional metabolism in acute COVID-19 illness.

20 Jan 2021

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation

Researchers develop a novel, simple and affordable method for N-glycan fingerprinting based on enzymatic fluorescent glycan labeling and electrophoresis. This new method may help us understand important changes in glycosylation in the SARS-CoV-2 spike protein – something which could inform future therapeutic research.

20 Jan 2021

Immune systems of COVID-19 patients may rely on antibodies from earlier coronaviruses

The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.

20 Jan 2021

Over 100 million in India may have been infected by SARS-CoV-2

A large new study posted on the preprint server medRxiv describes the seropositivity rate to this virus, as well as the persistence of antibodies over time, both neutralizing and others.

19 Jan 2021

Respiratory News and Research

Blood group associated with cardiovascular events in COVID-19 patients

ACE2 and furin levels linked to inflammation in smokers with COVID-19

Can cancer patients receive urgent care without risk of COVID-19?

Monocytes could be a key player in sarcoidosis pathogenesis, study shows

Yurts, igloos and pop-up domes: How safe is ‘outside’ restaurant dining this winter?

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Busting myths on airborne transmission of SARS-CoV-2

Potentially promising therapeutic combination for renal cell carcinoma uncovered

Nearly one third of UK's hospitalized COVID-19 patients readmitted

People with problems in the upper GI tract may be vulnerable to COVID-19 infection

COVID-19 has transformed the world of vaccines

South African SARS-CoV-2 variant escapes antibody neutralization

Mask-wearing together with social distancing has maximum impact on COVID-19, study finds

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

How does SARS-CoV-2 infect brain cells?

California is overriding its limits on nurse workloads as covid surges

Can metabolic biomarkers help clinicians stratify adverse outcome risk in COVID-19 patients?

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation

Immune systems of COVID-19 patients may rely on antibodies from earlier coronaviruses

Over 100 million in India may have been infected by SARS-CoV-2

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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