Antigen News and Research

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New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

The newly developed DCFHP-alum COVID-19 vaccine candidate is affordable and effective for mass vaccination.

18 Apr 2023

Novel assay based on hybrid DNA-RNA probe for detecting food contaminated with salmonella

A team of researchers have developed an easy-to-use colorimetric assay for the detection of food contaminated with salmonella.

18 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Relaxation of pandemic measures resulted in the surge of Strep A infections to above pre-COVID levels

New research from France shows that infections cause by Group A Streptococcus (GAS) fell by 80% as the first COVID lockdown took effect in March 2020 and stayed at low levels until March 2022, from which point they increased by 18% a month to rise well above pre-COVID levels.

17 Apr 2023

Vaccine component BNT162b4 enhances T-cell immunity against SARS-CoV-2 variants for reduced COVID-19 disease severity

Researchers designed a novel messenger ribonucleic acid (mRNA) vaccine component designated BNT162b4.

17 Apr 2023

Pregnant women show unique immune response to COVID-19

Researchers compare the adaptive, innate, and humoral immune responses between pregnant and non-pregnant women with COVID-19.

16 Apr 2023

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

Researchers investigate whether SARS-CoV-2 and its variants have evolved to evade CD8+ T cell-mediated immunity.

15 Apr 2023

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Researchers developed a novel intranasal vaccine candidate for coronavirus disease 2019 (COVID-19).

14 Apr 2023

B cells use mechanical force to pull antigen molecules off other cells

Most cells evolve slowly, accumulating incremental changes that better suit their environments. Immune cells, because they must adapt rapidly to counter new threats, evolve much more quickly.

13 Apr 2023

MHRA research evaluates two different approaches to cancer therapies

The report 'Antibody conjugates for targeted delivery of Toll-like receptor 9 agonist to the tumor tissue', published in the PLOS ONE journal, highlights MHRA research which showed that genetic engineering of antibodies used to activate and support the immune system against cancer leads to improvements in their reliability and effectiveness.

13 Apr 2023

New tool provides insight into the developmental history of certain immune cells

A new tool that can uncover the developmental history of certain immune cells is now freely available worldwide. The tool provides insights into the stages that immune cells go through in a healthy individual and how this can be impacted in disease.

13 Apr 2023

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

Reported the identification of a panel of vaccinee-derived antibodies with broad-spectrum neutralization activity.

12 Apr 2023

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Developing and testing new treatments or vaccines for humans almost always requires animal trials, but these experiments can sometimes take years to complete and can raise ethical concerns about the animals' treatment.

12 Apr 2023

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

In Brazil, a group of researchers supported by FAPESP created mutant forms of Salmonella to understand the mechanisms that favor colonization of the intestinal tract of chickens by these pathogenic bacteria and find better ways to combat the infection they cause.

11 Apr 2023

Study highlights the potential long-term neurological effects post-COVID-19

Researchers studied the presence of the SARS-CoV-2 spike protein in the skull-meninges-brain (SMB) axis.

10 Apr 2023

COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Pieren, D. K. J., Kuguel, S. G., Rosado, J., Robles, A. G., Rey-Cano, J., Mancebo, C., Esperalba, J., Falcó, V., Buzón, M. J., & Genescà, M. (2023). Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-37559-w, https://www.nature.com/articles/s41467-023-37559-w

10 Apr 2023

Study explores the association between gut microbiome dysbiosis and uveitis

Researchers provide an overview of existing research on the correlation between uveitis and gut dysbiosis.

7 Apr 2023

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Researchers assess the role of the live-attenuated vaccine sCPD9 in inducing systemic and mucosal immunity against SARS-CoV-2 variants.

6 Apr 2023

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Exploring the gut microbiome's role in rheumatoid arthritis pathogenesis

Researchers analyzed data on the association between intestinal microbiome dysbiosis and rheumatoid arthritis.

6 Apr 2023

Antigen News and Research

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

Novel assay based on hybrid DNA-RNA probe for detecting food contaminated with salmonella

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

Relaxation of pandemic measures resulted in the surge of Strep A infections to above pre-COVID levels

Vaccine component BNT162b4 enhances T-cell immunity against SARS-CoV-2 variants for reduced COVID-19 disease severity

Pregnant women show unique immune response to COVID-19

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

B cells use mechanical force to pull antigen molecules off other cells

MHRA research evaluates two different approaches to cancer therapies

New tool provides insight into the developmental history of certain immune cells

The identification of vaccinee-derived antibodies with broad-spectrum Omicron neutralization activity

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Mutant Salmonella strains cause more severe infections than wild-type bacteria in chickens

Study highlights the potential long-term neurological effects post-COVID-19

COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Study explores the association between gut microbiome dysbiosis and uveitis

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

Exploring the gut microbiome's role in rheumatoid arthritis pathogenesis

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