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Novel fatty liver organoid models could aid in drug discovery and testing

Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology established novel human organoid models of fatty liver disease.

23 Feb 2023

Safety of a gene therapy to treat alpha 1-antitrypsin deficiency

Researchers report on the safety of a gene therapy to treat the common autosomal recessive hereditary disorder alpha 1-antitrypsin (AAT) deficiency in a new article in the peer-reviewed journal Human Gene Therapy.

22 Feb 2023

Life Sciences Innovator Category Winner 2023

Following a rigorous application process, we are proud to announce that Seda have been selected as the UK Life Sciences Innovator Winner 2023 in the Application, Product & Service Design Category.

From Seda Pharmaceutical Development Services 21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Adipose-targeted delivery of thyroid hormone alleviates hypercholesterolemia and atherosclerosis

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has developed thyroid hormone (TH) - encapsulated nanoparticles modified with adipose-homing peptide, which selectively transport TH to adipose tissues.

20 Feb 2023

BioEcho receives patent for its EchoLUTION™ technology in the U.S. and Japan

BioEcho announces the grant of two patents for the innovative EchoLUTION™ technology transforming established nucleic acid extraction procedures.

From BioEcho Life Sciences GmbH 17 Feb 2023

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Metabolic engineering is a field of plant biotechnology that seeks to genetically modify plant metabolic pathways to generate plant varieties with improved health benefits.

17 Feb 2023

Innovative software tool assembles truly complete genome sequences from many species

National Institutes of Health researchers have developed and released an innovative software tool to assemble truly complete (i.e., gapless) genome sequences from a variety of species.

16 Feb 2023

Genetic features of the immune system linked to a person's ability to resist new COVID-19 variants

An international team including researchers from the HSE University Faculty of Biology and Biotechnology has found a link between certain genetic features of the immune system and one's ability to effectively resist new waves of COVID-19.

16 Feb 2023

Machine learning algorithm predicts DNA insertion efficiency of prime editing

A new tool to predict the chances of successfully inserting a gene-edited sequence of DNA into the genome of a cell, using a technique known as prime editing, has been developed by researchers at the Wellcome Sanger Institute.

15 Feb 2023

"AutoPLP" technique enables rapid, accurate detection of mutating bacteria and viruses

As we now know from our experience with the COVID-19 pandemic, the microbes responsible for some infections can rapidly mutate into variants that evade detection and treatment.

15 Feb 2023

Bread made from whole cell pulse flour simulates satiety hormones to help us feel full

Bread made from a new type of whole cell pulse flour can lower blood glucose (sugar) levels and keep you fuller for longer, new research has found.

10 Feb 2023

Assessing the zoonotic potential of different coronaviruses in hedgehogs, moles and shrews

Researchers examine the phylogenetic relationships between Eulipotyphla coronaviruses and related coronaviruses.

9 Feb 2023

Using patches of synthetic skin to test blood-sucking behavior of mosquitoes

If watching animals feast on human blood for 30-plus hours isn't your idea of fun, don't worry. The robot can do it.

9 Feb 2023

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

Researchers developed a WGS method that read four canonical DNA bases, viz., adenine (A), cytosine (C), guanine (G), and thymine (T) plus 5mC and 5hmC, epigenetic variants of unmodified C to yield an accurate six-letter digital readout in a single workflow.

9 Feb 2023

New synthetic skin to study mosquito feeding behavior

One by one, mosquitoes are captured by a handheld vacuum and released into a clear plastic box. After taking a moment to adjust to their new surroundings, the mosquitoes smell blood and swarm to the source.

9 Feb 2023

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein.

3 Feb 2023

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

To commemorate World Cancer Day, we spoke to a multidisciplinary team of researchers from The Institute of Cancer Therapeutics (ICT) based at the University of Bradford about their work in cancer research.

3 Feb 2023

Improving CAR-based-immunotherapies using a molecular anchor

Adding a molecular anchor to the key protein used to recognize cancer in cellular immunotherapies can make the treatments significantly more effective.

3 Feb 2023

UC Davis launches new institute to advance basic knowledge of psychedelics and neurotherapeutics

The University of California, Davis has launched the Institute for Psychedelics and Neurotherapeutics to advance basic knowledge about the mechanisms of psychedelics and translate it into safe and effective treatments for diseases such as depression, post-traumatic stress disorder, addiction, Alzheimer's disease and Parkinson's disease, among others.

2 Feb 2023

Biotechnology News and Research

Novel fatty liver organoid models could aid in drug discovery and testing

Safety of a gene therapy to treat alpha 1-antitrypsin deficiency

Life Sciences Innovator Category Winner 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Adipose-targeted delivery of thyroid hormone alleviates hypercholesterolemia and atherosclerosis

BioEcho receives patent for its EchoLUTION™ technology in the U.S. and Japan

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Innovative software tool assembles truly complete genome sequences from many species

Genetic features of the immune system linked to a person's ability to resist new COVID-19 variants

Machine learning algorithm predicts DNA insertion efficiency of prime editing

"AutoPLP" technique enables rapid, accurate detection of mutating bacteria and viruses

Bread made from whole cell pulse flour simulates satiety hormones to help us feel full

Assessing the zoonotic potential of different coronaviruses in hedgehogs, moles and shrews

Using patches of synthetic skin to test blood-sucking behavior of mosquitoes

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

New synthetic skin to study mosquito feeding behavior

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

Improving CAR-based-immunotherapies using a molecular anchor

UC Davis launches new institute to advance basic knowledge of psychedelics and neurotherapeutics

Event guide: 3rd IMPACCT Real World Evidence Summit Europe eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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