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Head injuries and long sleep deprivation can affect neurogenerative processes

Scientists from the School of Biomedicine of Far Eastern Federal University (FEFU) with colleagues from Italy, Spain, Romania, and Sweden suggest a way to protect the brain and minimize neurodegenerative processes after concussion head injuries in the presence of extensive previous sleep deprivation.

9 Dec 2020

Scientists determine key molecular processes used by coronavirus to infect human cells

When a coronavirus--including SARS-CoV-2, which causes COVID-19--infects someone, it hijacks the person's cells, co-opting their molecular machinery for its own survival and spread.

9 Dec 2020

Study shows how YTHDF3 plays a significant role in cancer metastasis

Approximately 200,000 cancer patients are diagnosed with brain metastases each year, yet few treatment options exist because the mechanisms that allow cancer to spread to the brain remain unclear.

9 Dec 2020

Chemists identify a new method to make valuable hydrocarbons

Inspired by light-sensing bacteria that thrive near hot oceanic vents, synthetic chemists at Rice University have found a mild method to make valuable hydrocarbons known as olefins, or alkenes.

8 Dec 2020

Amilorides reduce SARS-CoV-2 viral replication in vitro

A new U.S. study published on the bioRxiv preprint server reports the use of an amiloride-based scaffold that targets a viral RNA structure known to be essential in viral replication in the 5’-untranslated region (UTR) of the virus. The researchers say this heralds the application of these molecules as chemical probes to explore viral biology and produce specific antivirals targeting RNA regions of the coronavirus genome.

8 Dec 2020

GlycoNet scientists secure up to $4 million US investment to advance regenerative medicine

GlycoNet scientists Drs. Robert Ben and Jason Acker, who are revolutionizing the cryopreservation of cells, tissues and organs for human and veterinary therapies, have secured a $2-million USD equity investment for PanTHERA CryoSolutions (PanTHERA), a Canadian biotechnology start-up that they co-founded.

8 Dec 2020

Using magnetic bacteria to control liquids at the micro level

ETH scientists use magnetic bacteria to control liquids at the micro level. They are already thinking about using them in the human bloodstream for precision delivery of cancer drugs to a tumor.

8 Dec 2020

Researchers identify new gene variants that modify the risk of late-onset Alzheimer's disease

Late-onset Alzheimer's disease (LOAD) is the most common form of dementia in the elderly, affecting almost 44 million people worldwide.

8 Dec 2020

Research shows how targeted microbubbles can carry powerful cancer drugs

New research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumor using antibodies.

8 Dec 2020

OU Health Sciences Center receives federal grant for opioid management in older adults

Chronic pain can be quite common among older adults as they face conditions such as arthritis and neuropathy. Treating pain in older adults requires special considerations, however, especially when it comes to opioids.

8 Dec 2020

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large variety of specialized lipids with biological activity, this process includes the generation and release of pro and anti-inflammatory lipids.

8 Dec 2020

Bioactive tea compounds show potential anti-SARS-CoV-2 activity

Scientists have revealed that certain bioactive compounds found in green, black, and oolong tea possess remarkable antiviral activities against SARS-CoV-2.

8 Dec 2020

Mice study shows how COVID-19 damages organs other than the lungs

UCLA researchers are the first to create a version of COVID-19 in mice that shows how the disease damages organs other than the lungs.

8 Dec 2020

UCI researchers develop new technology to rapidly hypermutate antibodies

Using the same strain of yeast that ferments wine and makes dough rise, a team led by University of California, Irvine and Harvard Medical School researchers has developed an in vitro technology that can rapidly hypermutate antibodies.

8 Dec 2020

Oligourea-based "fake" peptides enhance options for rational drug design, shows study

Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units.

8 Dec 2020

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Primary central nervous system lymphoma (PCNSL) is a type of cancer that develops in the brain and or spinal cord.

7 Dec 2020

Drug prescribed for rare enzyme deficiency shows promise to treat herpes viruses

A drug currently prescribed to treat a rare enzyme deficiency can help cells clear the herpes simplex 1 and herpes simplex 2 viruses, according to a new study published in the journal Science Advances.

7 Dec 2020

Single-cell sequencing provides new fundamental insights into 'abdominal brain'

Researchers at Karolinska Institutet have succeeded in mapping the neuron types comprising the enteric nervous system in the intestine of mice.

7 Dec 2020

Research uncovers novel anti-craving mechanism to treat cocaine relapse

Cocaine continues to be one of the most commonly abused illicit drugs in the United States. Pre-clinical literature suggests that targeting glucagon-like peptide-1 receptors (GLP-1Rs) in the brain may represent a novel approach to treating cocaine use disorder.

7 Dec 2020

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

A team of researchers at the Feinberg School of Medicine demonstrated that xylitol and grapefruit seed extract (GSE) could prevent SARS-CoV-2 infection. These can be used as a nasal spray to contain the spread of the coronavirus.

7 Dec 2020

Drugs News and Research

Head injuries and long sleep deprivation can affect neurogenerative processes

Scientists determine key molecular processes used by coronavirus to infect human cells

Study shows how YTHDF3 plays a significant role in cancer metastasis

Chemists identify a new method to make valuable hydrocarbons

Amilorides reduce SARS-CoV-2 viral replication in vitro

GlycoNet scientists secure up to $4 million US investment to advance regenerative medicine

Using magnetic bacteria to control liquids at the micro level

Researchers identify new gene variants that modify the risk of late-onset Alzheimer's disease

Research shows how targeted microbubbles can carry powerful cancer drugs

OU Health Sciences Center receives federal grant for opioid management in older adults

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

Bioactive tea compounds show potential anti-SARS-CoV-2 activity

Mice study shows how COVID-19 damages organs other than the lungs

UCI researchers develop new technology to rapidly hypermutate antibodies

Oligourea-based "fake" peptides enhance options for rational drug design, shows study

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Drug prescribed for rare enzyme deficiency shows promise to treat herpes viruses

Single-cell sequencing provides new fundamental insights into 'abdominal brain'

Research uncovers novel anti-craving mechanism to treat cocaine relapse

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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