Immune System News and Research

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How maternal microbes shape babies’ gut health and disease risk

Early microbial exposures from maternal microbes, milk components, and the environment shape infant gut development and long-term disease risk. The review highlights mechanisms, preventive levers, and research gaps in supporting healthy microbiome inheritance across generations.

29 Sep 2025

New mRNA vaccine stops allergens from causing life-threatening inflammation in mice

A new mRNA vaccine stopped allergens from causing dangerous immune reactions and life-threatening inflammation in mice, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Cincinnati Children's.

29 Sep 2025

Affordable drug found to be effective in treating seriously ill COVID-19 patients

A widely available and affordable drug has been shown to be effective in treating seriously ill COVID-19 patients, according to a new international study led by researchers at the Australian National University (ANU) in collaboration with King's College London.

29 Sep 2025

RSV vaccines protect two most-at-risk groups from severe illness

The review demonstrates that vaccines for respiratory syncytial virus (RSV) are both safe and effective in protecting groups who are most at risk for serious illness, including older adults and infants.

29 Sep 2025

Pasteurized milk contains H5N1 proteins without posing health risks

Proteins and genetic material from H5N1 influenza viruses have been found in pasteurized milk in the United States, but a study from St. Jude Children's Research Hospital shows those inactive viral pieces represent little to no health risk.

26 Sep 2025

Novel treatment disrupts tumor immunosuppression in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate below 10%.

26 Sep 2025

New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies

Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers like lung and prostate cancer.

26 Sep 2025

Off-label drug helps one boy with autism speak, parents say. But experts want more data.

Caroline Connor's concerns about her son's development began around his 1st birthday, when she noticed he wasn't talking or using any words. Their pediatrician didn't seem worried, but the speech delay persisted. At 2½, Mason was diagnosed with autism.

26 Sep 2025

Researchers develop tool to predict how patients will respond to common multiple sclerosis drug

Brazilian researchers, in partnership with French institutions, have developed a tool that can predict how patients will respond to natalizumab, one of the most commonly used drugs for treating multiple sclerosis.

25 Sep 2025

Mucins show promise in preventing Salmonella infections

Mucus is more than just a sticky substance: It contains a wealth of powerful molecules called mucins that help to tame microbes and prevent infection.

25 Sep 2025

Study shows how early-life epigenetic 'memory' can influence adult brain inflammation

Why do some people remain healthy through childhood yet become more vulnerable to brain disorders such as dementia later in life? A KAIST (President Kwang Hyung Lee) -led team has uncovered a key part of the answer: a developmental 'switch' in astrocytes—the brain's most abundant support cells that shapes how strongly the brain's immune system reacts in adulthood.

25 Sep 2025

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Scientists conducted a multiomics study of the world’s oldest verified person (117 years), uncovering protective genetic, immune, metabolic, microbiome, and epigenetic traits that supported her exceptional longevity. These findings highlight how aging and disease may, under rare circumstances, be decoupled.

25 Sep 2025

Babies living with dogs show better lung function and reduced asthma rates

Babies exposed to dog allergens in the home have a lower risk of developing asthma by the age of five years, according to research that will be presented at the European Respiratory Society (ERS) Congress in Amsterdam, the Netherlands.

25 Sep 2025

Discovery of EP2 receptor opens path to pain relief without blocking inflammation

Scientists at the NYU Pain Research Center have identified which receptor in prostaglandins-the hormone-like substance targeted by common painkillers-causes pain but not inflammation.

25 Sep 2025

Study uncovers how lymphatic endothelial cells assist in generating robust immune memory

A study published today in Nature Communications describes how lymphatic endothelial cells assist in generating robust immune memory, offering new insights into how the immune system functions.

25 Sep 2025

AstroCapsules offer a new way to reduce brain inflammation

Neuroinflammation is linked to a host of detrimental brain disorders, including Alzheimer's and Parkinson's disease.

25 Sep 2025

New study suggests a connection between soft drinks and depression via the microbiome

A new study involving the German Center for Diabetes Research (DZD) provides strong evidence that sugary drinks affect not only metabolic but also mental health – especially in women. This effect is probably mediated by the sensitive microbiome of the intestine.

25 Sep 2025

Genetic modification enhances "living drugs" for blood cancers

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, with a "chimeric antigen receptor" (CAR) enables them to specifically recognize and attack cancer cells.

25 Sep 2025

New study reveals silent onset of rheumatoid arthritis

Scientists have discovered that rheumatoid arthritis (RA) doesn't start when the pain begins. It silently starts years earlier.

24 Sep 2025

Loss of Trp53 gene affects immune responses in ovarian cancer

A new research paper was published in Volume 16 of Oncotarget on September 22, 2025, titled "Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma."

24 Sep 2025

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Immune System News and Research

How maternal microbes shape babies’ gut health and disease risk

New mRNA vaccine stops allergens from causing life-threatening inflammation in mice

Affordable drug found to be effective in treating seriously ill COVID-19 patients

RSV vaccines protect two most-at-risk groups from severe illness

Pasteurized milk contains H5N1 proteins without posing health risks

Novel treatment disrupts tumor immunosuppression in pancreatic cancer

New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies

Off-label drug helps one boy with autism speak, parents say. But experts want more data.

Researchers develop tool to predict how patients will respond to common multiple sclerosis drug

Mucins show promise in preventing Salmonella infections

Study shows how early-life epigenetic 'memory' can influence adult brain inflammation

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Babies living with dogs show better lung function and reduced asthma rates

Discovery of EP2 receptor opens path to pain relief without blocking inflammation

Study uncovers how lymphatic endothelial cells assist in generating robust immune memory

AstroCapsules offer a new way to reduce brain inflammation

New study suggests a connection between soft drinks and depression via the microbiome

Genetic modification enhances "living drugs" for blood cancers

New study reveals silent onset of rheumatoid arthritis

Loss of Trp53 gene affects immune responses in ovarian cancer

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