Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

New algae-based treatment could reduce need for limb amputation

A new algae-based treatment could reduce the need for amputation in people with critical limb ischaemia, according to new research funded by the British Heart Foundation, published today in the journal npj Regenerative Medicine.

21 Mar 2019

Preclinical data shows combination immunotherapy could suppress tumor growth in the liver

Even as overall cancer incidence and mortality decrease in the United States, the number of people diagnosed with liver cancer is on the rise.

14 Mar 2019

Harmless purple bacteria can visualize aspects of tumor heterogeneity

Cancer presents an ongoing challenge for physicians, particularly in the diagnosis and treatment of the disease. This is, amongst other things, due to tumor heterogeneity.

14 Mar 2019

Avocado seed extract could be potential source for novel anti-inflammatory compounds

An extract from the seeds of avocados exhibited anti-inflammatory properties in a laboratory study, according to Penn State researchers, and it represents a potential source for novel anti-inflammatory compounds that could be developed as a functional food ingredient or pharmaceuticals.

13 Mar 2019

Zinc could help develop new non-antibiotic treatment for bacterial diseases

New details about the role of zinc in our immune system could help the development of new non-antibiotic treatment strategies for bacterial diseases, such as urinary tract infections.

9 Mar 2019

Researchers unravel how the immune system responds to diffuse cutaneous leishmanisis

In diffuse cutaneous leishmanisis, a rare form of leishmaniasis, parasites grow uncontrolled in skin lesions across the body.

8 Mar 2019

Up-to-date guidance for clinicians to treat HIV-related cardiovascular disease

Since the advent of effective antiretroviral therapy, human immunodeficiency virus infection has become more like a chronic illness.

5 Mar 2019

Multipotent stromal cells of diabetic patients have diminished antibacterial activity, study reveals

A new study reveals that the multipotent stromal cells (MSCs) of persons with diabetes have diminished capacity to fight off bacterial infection, providing new understanding into the basis of diabetes-associated immune dysfunction.

5 Mar 2019

Aging and high-fat diet disrupt gut microbiome to cause inflammation in heart failure

Growing older and a high-fat diet enriched with omega 6 fatty acids are major contributors to health risks ranging from diabetes to heart failure. How these two factors regulate the immune response is not well-understood.

1 Mar 2019

Lipid-filled particle plays role in immune function and metabolism

Researchers have discovered that fat tissue releases a lipid-filled particle that has a role in immune function and metabolism. The study, in mice, was published online in the journal Science.

1 Mar 2019

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses.

26 Feb 2019

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

Scientists at the University of British Columbia have discovered a new protein "switch" that could stop the progression of blood-poisoning, or sepsis, and increase the chances of surviving the life-threatening disease.

26 Feb 2019

Researchers develop highly sensitive cell model to study complex effects of anti-inflammatory drugs

Drugs such as ibuprofen or aspirin that relieve pain and lower fever are among the most frequently used drugs worldwide. They are used above all for the treatment of inflammatory reactions. However, in spite of their indisputable effectiveness and frequent use, we do not yet fully understand the underlying mechanisms of these drugs.

23 Feb 2019

Researchers identify origin of immune cell that helps form healthy heart valves

UCLA researchers have identified for the first time the origin of an immune cell that plays a critical role in the formation of healthy heart valves. The findings could pave the way for new treatments for heart valve disorders, which can be caused by congenital defects, aging or disease.

22 Feb 2019

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumors in several mouse models.

20 Feb 2019

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.

18 Feb 2019

Columbia researchers unravel why some glioblastomas respond to immunotherapy

Columbia researchers have learned why some glioblastomas--the most common type of brain cancer--respond to immunotherapy. The findings could help identify patients who are most likely to benefit from treatment with immunotherapy drugs and lead to the development of more broadly effective treatments.

17 Feb 2019

HDL proteome behaves like a tiny Velcro ball that is rolling on surfaces

Cholesterol carried in high-density lipoprotein particles, or HDL cholesterol, has been dubbed the good cholesterol, because people whose HDL levels are high have a lower risk of developing heart disease. That link was first established in 1977 and has been confirmed over and over in epidemiological studies.

15 Feb 2019

Study shows how neuroactive steroids inhibit activity of pro-inflammatory proteins

For the first time, scientists discovered how neuroactive steroids naturally found in the brain and bloodstream inhibit the activity of a specific kind of protein called Toll-like receptors, which have been known to play a role in inflammation in many organs, including the brain.

14 Feb 2019

Study identifies protein regulator that induces Th17 cells to cause multiple sclerosis

Inflammatory and autoimmune diseases such as psoriasis, rheumatoid arthritis, and multiple sclerosis (MS) are a major healthcare burden worldwide and are life-altering conditions for afflicted patients.

14 Feb 2019

Macrophage News and Research

Further Reading

New algae-based treatment could reduce need for limb amputation

Preclinical data shows combination immunotherapy could suppress tumor growth in the liver

Harmless purple bacteria can visualize aspects of tumor heterogeneity

Avocado seed extract could be potential source for novel anti-inflammatory compounds

Zinc could help develop new non-antibiotic treatment for bacterial diseases

Researchers unravel how the immune system responds to diffuse cutaneous leishmanisis

Up-to-date guidance for clinicians to treat HIV-related cardiovascular disease

Multipotent stromal cells of diabetic patients have diminished antibacterial activity, study reveals

Aging and high-fat diet disrupt gut microbiome to cause inflammation in heart failure

Lipid-filled particle plays role in immune function and metabolism

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

Researchers develop highly sensitive cell model to study complex effects of anti-inflammatory drugs

Researchers identify origin of immune cell that helps form healthy heart valves

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

Columbia researchers unravel why some glioblastomas respond to immunotherapy

HDL proteome behaves like a tiny Velcro ball that is rolling on surfaces

Study shows how neuroactive steroids inhibit activity of pro-inflammatory proteins

Study identifies protein regulator that induces Th17 cells to cause multiple sclerosis

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