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Single mutation in (HPAI) H5N1 influenza virus could increase human transmission risk

A single modification in the protein found on the surface of the highly pathogenic avian influenza (HPAI) H5N1 influenza virus currently circulating in U.S. dairy cows could allow for easier transmission among humans, according to new research funded by the National Institutes of Health (NIH) and published today in the journal Science.

9 Dec 2024

SigRM offers breakthrough in single-cell epitranscriptomics analysis

Researchers have developed a new tool that will help scientists study how genes are expressed in our cells.

6 Dec 2024

New collaborative effort aims to cure ALK-positive lung cancer

Lung cancer is the leading cause of cancer death worldwide, with various subtypes affecting millions of people each year.

6 Dec 2024

Cancer prevention and screening avert more deaths than treatment advances

Improvements in cancer prevention and screening have averted more deaths from five cancer types combined over the past 45 years than treatment advances, according to a modeling study led by researchers at the National Institutes of Health (NIH).

5 Dec 2024

Can AI fix the peer review bottleneck? Top journals weigh in

Study examines AI's role in peer review among top 100 medical journals, revealing that while most journals provide AI guidelines, a majority prohibit its use due to confidentiality and ethical concerns. The findings highlight varied policies and emphasize the need for clear, unified guidance for AI integration in peer review.

5 Dec 2024

Dupilumab improves symptoms of atopic dermatitis in children with co-existing conditions

Research at National Jewish Health and other institutions has shown that the biologic dupilumab improves signs and symptoms of moderate-to-severe atopic dermatitis (eczema) in young children whether or not they have another inflammatory condition, such as asthma, allergic rhinitis or food allergies.

5 Dec 2024

Discovery of leptin-responsive neurons offers new hope for obesity treatment

Obesity affects a staggering 40 percent of adults and 20 percent of children in the United States. While some new popular therapies are helping to tackle the epidemic of obesity, there is still so much that researchers do not understand about the brain-body connection that regulates appetite.

5 Dec 2024

Prenatal cfDNA testing uncovers hidden cancers in pregnant individuals

Researchers at the National Institutes of Health (NIH) found previously undetected cancers in 48.6% of pregnant people who had abnormal results for prenatal cell-free DNA (cfDNA) testing used to screen for chromosomal disorders in the fetus.

4 Dec 2024

Aging reduces cancer risk by limiting cell regeneration

When it comes to cancer, aging is a double-edged sword, researchers are increasingly learning.

4 Dec 2024

New research sheds light on how monkeys avoid hepatitis B infection

Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases, that spreads among individuals through blood or body fluids.

4 Dec 2024

Researchers discover new cause of cytokine storm in COVID-19

As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children's Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause of cytokine storm - the extreme inflammatory response associated with increased risk of death in COVID-19 infection.

2 Dec 2024

Ultra-processed foods increase active psoriasis risk, study shows

This study highlights a significant link between high ultra-processed food (UPF) consumption and active psoriasis, independent of BMI and other factors. The findings emphasize UPFs' contribution to proinflammatory pathways in individuals with this chronic skin condition.

1 Dec 2024

UQ researchers move closer to developing topical cream for skin cancers in transplant patients

A topical cream to help prevent and treat skin cancers in organ transplant patients is a step closer to development.

28 Nov 2024

Fossil fuel industry influences medical research, raising ethical concerns

An investigation published by The BMJ today reveals the extent of fossil fuel industry involvement in medical research, leading to fresh calls for academics and publishing companies to cut ties with companies.

28 Nov 2024

PD-1 deficiency reveals the impact of checkpoint inhibition on B cell function

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint inhibitors experience increased susceptibility to common infections.

27 Nov 2024

WHO and partners announce grants to boost pathogen genomic surveillance

The World Health Organization (WHO) and partners announced 10 projects that will receive almost US$ 2 million in grants to improve capacities in pathogen genomic surveillance.

26 Nov 2024

Cardiovascular disease risk linked to early brain decline in men

Men with cardiovascular disease risk factors, including obesity, face brain health decline a decade earlier - from their mid 50s to mid 70s - than similarly affected women who are most susceptible from their mid 60s to mid 70s, suggest the findings of a long term study, published online in the Journal of Neurology Neurosurgery & Psychiatry.

26 Nov 2024