OCT News and Research

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Successful treatment of metastatic malignant glomus tumor with BRAF and MEK inhibitors

A new case report was published in Oncotarget's Volume 15 on October 11, 2024, entitled "Complete response to encorafenib plus binimetinib in a BRAF V600E-mutant metastasic malignant glomus tumor."

29 Oct 2024

Researchers develop new approach to predict immunotherapy response in breast cancer patients

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to assess which patients with metastatic triple-negative breast cancer could benefit from immunotherapy.

29 Oct 2024

New insights into cardiac defects in Myotonic Dystrophy Type 1

People with Myotonic Dystrophy Type 1 (DM1), the most common adult-onset form of muscular dystrophy, progressively lose muscle mass and strength in their lower legs, hands, neck and face.

29 Oct 2024

Family violence found to have severe long-term health effects

A new synthesis of global evidence highlights a strong connection between family violence and long-term health consequences, significantly impacting the psychological and physical well-being of millions worldwide.

29 Oct 2024

Patient symptom information enhances MRI accuracy for lumbar spine diagnosis

Knowing a patient's symptoms helps radiologists in lumbar spine MRI interpretation and diagnosis, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

29 Oct 2024

AI model could help clinicians to understand prostate tumor's aggressiveness

Prostate cancer is the second most common cancer in men, and almost 300,000 individuals are diagnosed with it each year in the U.S.

29 Oct 2024

Study finds no benefit of routine orbital atherectomy in cardiac stenting

Routine use of an orbital atherectomy device to remove calcium from severely blocked coronary arteries before patients undergo cardiac stenting procedures does not improve outcomes, a Mount Sinai-led study has found.

29 Oct 2024

Social media analysis reveals patterns in seasonal allergies

Complaining about your allergies online might provide valuable data to researchers. Over 25% of Americans experience seasonal allergies, but how the prevalence of seasonal allergies varies across space and time remains obscure, in part because allergies seldom warrant visits to healthcare providers.

29 Oct 2024

Study aims to identify clinical subtypes in patients with schizophrenia

A research team led by Professor Takahiro Nemoto at Toho University, in collaboration with Associate Professor Naoki Hashimoto and Assistant Professor Ryo Okubo at Hokkaido University, and Dr. Satoru Ikezawa at the National Center of Neurology and Psychiatry explored the agreement or discrepancy between subjective social cognitive difficulties and actual cognitive impairment.

29 Oct 2024

New study to investigate the effectiveness of care provided in children's homes

The effectiveness of care provided in children's homes will be investigated in a new study by Kingston University, London, the National Children's Bureau and Ofsted.

29 Oct 2024

Innovative method promises quick cancer diagnosis using ultrathin membranes

There are billions of tiny packets of cellular material called extracellular vesicles (EVs) that are produced by cells and released into each person's blood, saliva, and other bodily fluids.

29 Oct 2024

Study uncovers six cancer susceptibility genes

Scientists at deCODE genetics/Amgen, and their collaborators have discovered six novel genes with rare germline variants that associate with cancer risk. The findings are published today in Nature Genetics under the title "Gene-based burden tests of rare germline variants identify six cancer susceptibility genes".

29 Oct 2024

Vance wrongly blames rural hospital closures on immigrants in the country illegally

During a recent presidential campaign rally in Wisconsin, Sen. JD Vance (R-Ohio) was asked how a Trump administration would protect rural health care access in the face of hospital closures, such as two this year in Eau Claire and Chippewa Falls.

29 Oct 2024

‘Dreamers’ can enroll in ACA plans this year — but a court challenge could get in the way

When open enrollment for the Affordable Care Act, or Obamacare, starts nationwide this week, a group that had previously been barred from signing up will be eligible for the first time: The "Dreamers." That's the name given to children brought to the United States without immigration paperwork who have since qualified for the Deferred Action for Childhood Arrivals program.

29 Oct 2024

Genetic marker could revolutionize neonatal sepsis diagnosis

A genetic signature in newborns can predict neonatal sepsis before symptoms even start to show, according to a new study.

29 Oct 2024

Unraveling the mystery of cancer resistance

Every multicellular creature - whether soaring through the skies, swimming in the ocean's depths or roaming the earth's surface - shares a common vulnerability: the uncontrolled growth of cells known as cancer.

29 Oct 2024

A promising new strategy for malaria drug development

Malaria kills over 600,000 people a year, and as the climate warms, the potential range of the disease is growing. While some drugs can effectively prevent and treat malaria, resistance to those drugs is also on the rise.

29 Oct 2024

Study reveals AI's potential and pitfalls in medical diagnosis

Published in JAMA Network Open, a collaborative team of researchers from the University of Minnesota Medical School, Stanford University, Beth Israel Deaconess Medical Center and the University of Virginia studied how well doctors used GPT-4 - an artificial intelligence (AI) large language model system - for diagnosing patients.

28 Oct 2024

Prenatal cannabis exposure linked to poorer child development

As cannabis is legalized and is more accessible in various forms across the country, there is increasing concern among health care providers about potential impact on children. Researchers at Nationwide Children's Hospital have new findings to add to the existing evidence that cannabis exposure before birth can negatively impact children.

28 Oct 2024