Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Researchers find link between estrogen levels in lung tissue and SMLA in postmenopausal women

Thanks to advances in medical imaging, the detection rate for synchronous multiple lung adenocarcinoma (SMLA) has been on the rise. Cases of SMLA in Japanese women have been on the rise despite having a national smoking rate of less than 10% in recent years.

26 Oct 2016

WSU researchers identify potential new diagnostic tool for early detection of colorectal cancer

Scientists at Washington State University and Johns Hopkins Medical School have discovered a fast, noninvasive method that could lead to the early diagnosis of colorectal cancer.

25 Oct 2016

Benefit and harm of tandem mass spectrometry screening for tyrosinaemia type 1 remain unclear

Tyrosinaemia type 1 is a rare, hereditary metabolic disease that, if left untreated, can already lead to serious liver and kidney damage in infancy.

25 Oct 2016

Scientists suggest potential approach of lowering tau levels to thwart Alzheimer's disease

Taking a pill that prevents the accumulation of toxic molecules in the brain might someday help prevent or delay Alzheimer's disease, according to scientists at Baylor College of Medicine, Texas Children's Hospital and Johns Hopkins University School of Medicine.

21 Oct 2016

Researchers identify proteins in the blood that could improve detection of pancreatic cancer

Pancreatic cancer is one of the most lethal forms of cancer because early stage symptoms are relatively light, often resulting in it being discovered only after spreading to other organs. In order to improve the prognosis of pancreatic cancer, the development of methods for early detection of pancreatic cancer with a blood test is important.

21 Oct 2016

Neu5Gc common in red meat increases risk of tumor formation

Neu5Gc, a non-human sialic acid sugar molecule common in red meat that increases the risk of tumor formation in humans, is also prevalent in pig organs, with concentrations increasing as the organs are cooked, a study by researchers from the UC Davis School of Medicine and Xiamen University School of Medicine has found.

19 Oct 2016

Study provides specific information about characteristics of dust mite allergens

Scientists from the National Institutes of Health have determined what differentiates dust mite allergens from the non-allergen proteins dust mites produce.

19 Oct 2016

How could emerging technologies impact cancer care?

The major innovations in cancer diagnosis, therapy/palliative care and surgical intervention are too numerous to list here. But enormous strides have taken place in stem cell therapy, monoclonal antibody therapy and genetic screening.

17 Oct 2016

New lab-on-a-chip system can detect effects of toxic substances on hemoglobin in blood

A new lab-on-a-chip system, developed by the University of Twente in The Netherlands, is capable of fast analysis of the effects of toxic substances on hemoglobin, for example. It mimicks human metabolism.

4 Oct 2016

Crick researchers find promising target for new tuberculosis drugs

Scientists led by Dr Luiz Pedro Carvalho at the Francis Crick Institute in London have found a promising new target in the search for new tuberculosis drugs. In the process, they say they've proven the strengths of a new research technique called metabolomics.

20 Sep 2016

Scientists begin research work at new £650 million Francis Crick Institute building

The first scientists have moved into the new £650 million Francis Crick Institute building in London and are starting work in their purpose-built labs.

20 Sep 2016

New test developed by Loughborough University may offer one-stop diagnosis for asthma

A new test which can diagnose asthma from a patient's saliva has been developed by Loughborough University.

16 Sep 2016

Genome-wide studies reveal evolutionary conserved enzyme facilitates DNA replication

Genome-wide studies of fission yeast (Schizosaccharomyces pombe) suggest that the evolutionary conserved enzyme Pfh1 helicase facilitates DNA synthesis by tracking along with the replication apparatus, promoting intact DNA synthesis at hard-to-replicate sites and consequently suppressing DNA damage. The findings are published in PLOS Genetics.

12 Sep 2016

Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

In a novel controlled clinical trial, participants in a six-day Ayurvedic-based well-being program that featured a vegetarian diet, meditation, yoga and massages experienced measurable decreases in a set of blood-based metabolites associated with inflammation, cardiovascular disease risk and cholesterol regulation.

9 Sep 2016

Experts develop urine-based method to diagnose conditions in newborn babies

Experts from the V. I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology and the Moscow Institute of Physics and Technology have devised a method that uses the urinary proteome to diagnose conditions in newborn babies.

9 Sep 2016

IWGAV establishes strategic recommendations for validating antibody specificity

The International Working Group on Antibody Validation, an independent group of international scientists with diverse research interests in the field of protein biology, today announced the publication of initial strategies developed to address a critical unmet need for antibody specificity, functionality and reproducibility in the September online issue of Nature Methods.

8 Sep 2016

Six NIH-funded projects aim to identify biological factors that affect neural regeneration

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina.

2 Sep 2016

Studying mutant peptides may help detect weaknesses in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins based on mass spectrometry data and the results of exome sequencing.

29 Aug 2016

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

BRAF mutation occurs in between 40% and 50% of metastasising melanomas (skin cancers), boosting tumour growth.