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SARS-CoV-2 viral antigens found in non-pulmonary tissues in recovering patients

A team of researchers in Singapore, led by Dr. Joe Yeong, and Prof. Tony Kiat Hon Lim, have reported the presence of residual SARS-CoV-2 ribonucleic acid (RNA) – the virus' genetic material – in stool samples and gastrointestinal tissues from patients recovering from the coronavirus disease 2019 (COVID-19).

8 Nov 2020

Delirium common after hospital discharge in critically ill COVID-19 patients

Anesthesiologist and other researchers from Michigan Medicine, Ann Arbor, New York Medical College, Valhalla and Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, have reported a case series of critically ill coronavirus disease 2019 (COVID-19) patients who have developed neuropsychological symptoms after having been discharged from the hospital.

8 Nov 2020

Study shows SARS-CoV-2 infection four times more likely through household transmission than community

A group of researchers from across the United States working in collaboration with their Swiss counterparts have conducted an extensive population-based serological survey to understand the transmission dynamics of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) – the novel agent that causes coronavirus disease 2019 (COVID-19).

8 Nov 2020

Decreasing humidity in the winter is likely to lead to more COVID-19 cases

A team of researchers from the Center for Disease Dynamics, Economics & Policy, USA, and Johns Hopkins University, USA, found evidence to support the notion that increased humidity may have contributed to lesser cases in spring earlier this year (2020). However, as the winter season fast approaches, the researchers fear that the decreasing humidity is likely to lead to an increase in COVID-19 cases.

8 Nov 2020

Cats shed SARS-CoV-2 RNA for a shorter duration compared to humans, study finds

Since the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease 2019 (COVID-19), there have been numerous reports of pets becoming infected. Both dogs and cats have been observed to exhibit symptoms of infection.

8 Nov 2020

Innate immunity key to limiting viral load in COVID-19 cases

As the coronavirus disease 2019 (COVID-19) pandemic continues to cause many difficulties for public health authorities, research is ongoing to understand how the virus can cause fatal effects on those infected and thereby suggest effective preventive and therapeutic measures against it.

8 Nov 2020

Study shows increasing size of respiratory droplets under cold humid conditions

Considerable evidence has accumulated to suggest that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus may spread through prolonged or brief contact with infected patients - with the infection being spread through respiratory droplets and aerosols. The need to understand how these infectious droplets behave becomes ever more urgent. A recent study published in the preprint server medRxiv* in October 2020 reports the results of such an investigation.

8 Nov 2020

Second wave of COVID-19 in UK has reached “critical” stage, says study

The current paper reports the preliminary findings of the sixth round of the REal-time Assessment of Community Transmission-1 (REACT-1) study, which has traced the path of the outbreak in England since May this year (2020).

8 Nov 2020

Universal nanoparticle platform may help in rapid development of a COVID-19 vaccine

A research group in China recently published a paper on the pre-print server bioRxiv* that reports the performance of a potentially universal nanoparticle platform that may prove useful for the rapid development of a COVID-19 vaccine, as well as other vaccines in the future.

8 Nov 2020

Study shows low incidence of COVID-19 infection in people with rheumatic diseases

A new study shows that the COVID-19 infection incidence has been low in people with rheumatic diseases, and most of those infected experience a mild course of illness.

6 Nov 2020

Study: Genetically edited form of herpes simplex virus outperforms leading vaccine candidate

A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.

6 Nov 2020

How do low levels of oxygen damage the brain?

In this interview, Professor Paul Tesar and Kevin Allan speak to News-Medical about how low levels of oxygen damage the brain.

6 Nov 2020

Rapid rise in CRP levels predicts COVID-19 outcomes

Predicting the course of a COVID-19 patient's disease after hospital admission is essential to improving treatment.

6 Nov 2020

COVID-19 hospitalizations and deaths skew towards older males of non-European ancestry

A team of researchers recently investigated the genetic determinants of COVID-19 risk and severity in humans.

6 Nov 2020

Anxiety disorders increase among US citizens during COVID-19 pandemic

Scientists from the University of North Carolina and City University New York have recently revealed that a majority of United States citizens have suffered from anxiety disorders amid the coronavirus disease 2019 (COVID-19) pandemic. Financial adversity is one of the major causative factors for anxiety symptoms. The study is currently available on the medRxiv* preprint server.

5 Nov 2020

A digital CRISPR-based method for quick detection and absolute quantification of SARS-CoV-2

In a recent medRxiv* preprint manuscript, researchers from Singapore and the United States report the development of a digital CRISPR method for the sensitive, specific, and rapid detection of viral nucleic acids at a constant temperature, which could be exploited for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Nov 2020

New Zealand case study shows room for improvement in genomic sequencing of COVID-19 outbreaks

Researchers in New Zealand, the United States and Australia have demonstrated the effectiveness of real-time genomic sequencing at tracking the re-emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New Zealand, in August this year.

5 Nov 2020

Pre-existing anti-IFN autoantibodies may worsen COVID-19 in lupus patients

“Our observations suggest that the presence of these autoantibodies may predispose SLE patients to infection with SARS-CoV-2 with a more severe presentation and represent an additional risk factor in this patient population,” write Sarthak Gupta and colleagues from the National Institute of Arthritis and Musculoskeletal and Skin Diseases in Bethesda, Maryland.

5 Nov 2020

Persistent and extensive lung damage seen in COVID-19 patients

A team of researchers at the University of Trieste in Italy aimed to determine the extent and the causes of lung damage from COVID-19 to better understand the pathological correlates of the disease.

5 Nov 2020

Llama antibodies could be a potent nanoweapon against COVID-19

Today in Science, researchers at the University of Pittsburgh School of Medicine describe a new method to extract tiny but extremely powerful SARS-CoV-2 antibody fragments from llamas, which could be fashioned into inhalable therapeutics with the potential to prevent and treat COVID-19.

5 Nov 2020