Protein C News and Research

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SMC protein complex plays a decisive role in the dynamics of holocentromeres

Monocentromeres are typical for the chromosomes of most animals and plants. The centromere is necessary for the transport of the chromosomes and represents the connection point between the chromatids.

6 Aug 2021

Study: IgG antibodies against SARS-CoV-2 remain stable, or even increase, seven months after infection

The levels of IgG antibodies against SARS-CoV-2 Spike protein remain stable, or even increase, seven months after infection, according to a follow-up study in a cohort of healthcare workers coordinated by the Barcelona Institute for Global Health, an institution supported by "la Caixa" Foundation, in collaboration with the Hospital Clinic of Barcelona.

6 Aug 2021

Researchers develop a novel process for producing pure RNA

Researchers at the University of Massachusetts Amherst recently unveiled their discovery of a new process for making RNA.

6 Aug 2021

University of Pittsburgh invests in Canopy Biosciences’ ChipCytometry instrument for spatial biology

Canopy Biosciences, a Bruker Company, today announced that the University of Pittsburgh will add ChipCytometry for high-plex single-cell spatial biology to its capabilities at the Unified Flow Core in the Department of Immunology

From Bruker Nano Surfaces and Metrology 6 Aug 2021

Simplified glycan modeling of the SARS-CoV-2 spike protein

In a research paper recently uploaded to the preprint server bioRxiv* by Gecht et al. (August 4th, 2021), a new method of representing glycan conformers on static protein structures is explored, named GlycoSHIELD.

6 Aug 2021

New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

A new study discusses the development of an improved protocol based on cell lines that can consistently express S proteins.

5 Aug 2021

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

A new study has revealed the mechanism by which the SARS-CoV-2 N protein activates NLRP3 inflammasomes to induce hyperinflammation.

5 Aug 2021

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

Shuo Ma, MD, '00 PhD, associate professor of Medicine in the Division of Hematology and Oncology, was co-first author of the clinical trial published in Blood.

5 Aug 2021

COVID vaccines generate antibodies in saliva

Researchers in the United States and Canada have conducted a study showing that the vaccines developed by Pfizer-BioNTech and Moderna to protect against coronavirus disease 2019 (COVID-19) generate local antibody responses in the salivary gland that are independent of the systemic immune response.

5 Aug 2021

Vaccination may protect against SARS-CoV-2 infection at the eye surface

Researchers in Australia have conducted a study showing that vaccination against coronavirus disease 2019 (COVID-19) induces key antibodies at the eye surface that may help to protect against the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Aug 2021

Study reveals structural differences and unique polymorphs in amyloid-β fibrils

Alzheimer's disease (AD) is a neurological condition leading to dementia that worsens with age as patients exhibit cognitive, memory, and psychological deficits.

5 Aug 2021

Research suggests potential new treatment strategy for phenylketonuria

Researchers at The University of Texas MD Anderson Cancer Center have discovered a critical new factor in regulating phenylalanine metabolism and, therefore, in preventing the inherited metabolic disorder phenylketonuria (PKU).

5 Aug 2021

Immune system signaling molecule promotes the production of energy-burning 'beige fat'

An immune signal promotes the production of energy-burning "beige fat," according to a new study publishing August 5th in the open-access journal PLOS Biology by Zhonghan Yang of Sun Yat-Sen University, Guangzhou, China, and colleagues.

5 Aug 2021

Researchers develop the most comprehensive molecular map of lung squamous cell carcinoma

Lung cancer remains the leading cause of cancer-associated death in the United States and worldwide. Patients with a subtype called lung adenocarcinoma (LUAD) have benefited from the development of new targeted medicines, but the search for effective new therapies for another subtype called lung squamous cell carcinoma (LSCC) has largely come up short.

5 Aug 2021

Scientists urge increased attention to persistent COVID-19 infections in immunocompromised people

In an article in the New England Journal of Medicine, scientists from Fred Hutchinson Cancer Research Center, Johns Hopkins Bloomberg School of Medicine, the U.S. Military HIV Research Program and the Institute for Global Health and Infectious Diseases at the University of North Carolina urged increased attention to persistent COVID-19 infections in immunocompromised people.

5 Aug 2021

Protein C News and Research

SMC protein complex plays a decisive role in the dynamics of holocentromeres

Study: IgG antibodies against SARS-CoV-2 remain stable, or even increase, seven months after infection

Researchers develop a novel process for producing pure RNA

University of Pittsburgh invests in Canopy Biosciences’ ChipCytometry instrument for spatial biology

Simplified glycan modeling of the SARS-CoV-2 spike protein

New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

COVID vaccines generate antibodies in saliva

Vaccination may protect against SARS-CoV-2 infection at the eye surface

Study reveals structural differences and unique polymorphs in amyloid-β fibrils

Research suggests potential new treatment strategy for phenylketonuria

Immune system signaling molecule promotes the production of energy-burning 'beige fat'

Researchers develop the most comprehensive molecular map of lung squamous cell carcinoma

Scientists urge increased attention to persistent COVID-19 infections in immunocompromised people

Specific and sensitive biomarker in the blood predicts symptomatic COVID-19 infection

Experimental drug combination extends survival in mice with lung cancer, study finds

Mutation in a single gene may be responsible for non-obstructive azoospermia in men

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Low glycemic diet results in important improvements for people with diabetes

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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