Immune System News and Research

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New molecule offers a more targeted and potent immunotherapy

A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and University Hospital Basel, Switzerland, have demonstrated that this fusion protein can both block the "do not attack" signal used by cancer cells and selectively activate tumor-fighting immune cells. This dual action could pave the way for more effective cancer therapies with fewer side effects.

18 Sep 2025

Special subgroup of bifidobacteria found to reduce antibiotic resistance in infants

Researchers from the Technical University of Denmark, DTU, document that a special subgroup of naturally occurring bifidobacteria plays a crucial role in reducing antibiotic resistance in infants.

17 Sep 2025

New findings show lymph nodes educate T cells to combat disease

A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the cellular and molecular interactions revealing how lymph nodes play a crucial role in the fight against chronic infection and cancer.

17 Sep 2025

Neurons play a key role in reducing lung inflammation in pulmonary fibrosis

Researchers at the University of Calgary studying a lethal lung disease called pulmonary fibrosis have found neurons, which were known to help detect pain, are also critical for reducing harmful lung inflammation that leads to the disease.

16 Sep 2025

Lymphatic vessels found to undergo dramatic changes during kidney transplant rejection

Scientists have uncovered how lymphatic vessels – the kidney's 'plumbing system' – undergo dramatic changes during chronic transplant rejection, becoming structurally disorganised and spreading to unusual parts of the kidney.

16 Sep 2025

Researchers uncover how HIV-1 uses RNA:DNA hybrids to integrate into the genome

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome.

16 Sep 2025

Triple negative breast cancer exploits lymph node niches to block immune defense

In almost all solid tumors - i.e. cancers with a solid tissue structure - the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease.

16 Sep 2025

Study uncovers the tradeoff between fast immune defense and long-term inflammation

Some of our biggest threats can come in the tiniest forms-viruses and bacteria. Thankfully, we are born with a built-in defense system, our innate immune system that protects us in our youth but can turn against us as we age.

16 Sep 2025

Scientists find a smarter way to activate the immune system against cancer

Scientists have developed a smarter way to activate the immune system against cancer, potentially making treatments safer and more precise.

16 Sep 2025

Researchers receive new funding to advance promising therapy for multiple sclerosis

A Canadian-led international research team, spearheaded by Dr. Fang Liu at the Centre for Addiction and Mental Health (CAMH) has received nearly $800,000 US ($1,137,868 CAD) in new funding to advance a promising therapy for multiple sclerosis (MS).

15 Sep 2025

Mediterranean diet during pregnancy cuts babies’ food allergy risk

Researchers found that mothers who closely followed a Mediterranean diet during pregnancy and breastfeeding had infants with lower odds of developing food allergies. High fruit, vegetable, and full-fat dairy intake appeared protective, while higher poultry, red meat, and fish intake during pregnancy increased risk.

15 Sep 2025

Study reveals how centenarians preserve youthful immune defenses

Researchers mapped immune cells from centenarians, their offspring, and younger controls across three cohorts using multi-omics single-cell profiling. They found that centenarians retain leaner helper pools but have enhanced cytotoxic and NK cell programs, along with reinforced NK–T communication networks.

15 Sep 2025

SwRI and UT San Antonio advance biosensor coating to streamline production of immunotherapies

Southwest Research Institute (SwRI) and The University of Texas at San Antonio (UT San Antonio) are advancing a smart biosensor coating to streamline the production of immunotherapies for cancer treatments.

15 Sep 2025

Mediterranean diet linked to better gum health

People living in the UK and following a diet close to the Mediterranean diet are more likely to have better gum health, with potentially lower amounts of gum disease and inflammation.

15 Sep 2025

High BMI and obesity may not always increase mortality risk

It is possible to be "fat but fit", new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) suggests.

15 Sep 2025

UCLA team develops engineered antibodies to fight cytomegalovirus infection

A UCLA research team has found a new way to prompt the immune system to kill cells infected with cytomegalovirus (CMV), a life-threatening infection that is particularly deadly in immunocompromised people.

13 Sep 2025

Bacteria use density switch to balance virulence and growth

Pathogens are becoming more and more resistant to antibiotics. With the goal of developing new therapeutic approaches to treat bacterial infections more effectively in the future, researchers at the Karlsruhe Institute of Technology (KIT) and the Max Planck Institute in Marburg investigated the plague-related bacterium Yersinia enterocolitica.

12 Sep 2025