Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Study points to TMPRSS2 gene as culprit for aggressive forms of androgen-fuelled cancers

A new study led by University of Toronto researcher Dr. David Lam has discovered the trigger behind the most severe forms of cancer pain. Released in top journal Pain this month, the study points to TMPRSS2 as the culprit: a gene that is also responsible for some of the most aggressive forms of androgen-fuelled cancers.

24 Apr 2015

Adseverin protein plays key role in bone loss associated with osteoinflammatory disease

Adseverin, a protein found in the body, has been identified as the key driver behind the bone loss associated with the world's most common inflammatory disease: gum disease, or periodontitis.

23 Apr 2015

Particle Sciences receives patent for its surface arrayed therapeutics drug delivery platform

Particle Sciences, a leading drug delivery CDMO, has received a Notice of Allowance for composition and use of the technology incorporated into its SATx™ platform...

9 Apr 2015

Scientists identify small RNA molecule that can suppress cancer-causing genes in GBM

Northwestern Medicine scientists have identified a small RNA molecule called miR-182 that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.

6 Apr 2015

Simple test outperforms current standard test for early-stage prostate cancer

A test that costs less than a $1 and yields results in minutes has been shown in newly published studies to be more sensitive and more exact than the current standard test for early-stage prostate cancer.

6 Apr 2015

Nanoparticle technique inhibits tumor growth, prolongs survival in animal models

Delving into the world of the extremely small, researchers are exploring how biodegradable nanoparticles can precisely deliver anticancer drugs to attack neuroblastoma, an often-deadly children's cancer.

3 Apr 2015

Biomedical researchers successfully convert microbubble technology into nanoparticles

Biomedical researchers led by Dr. Gang Zheng at Princess Margaret Cancer Centre have successfully converted microbubble technology already used in diagnostic imaging into nanoparticles that stay trapped in tumours to potentially deliver targeted, therapeutic payloads.

31 Mar 2015

Experimental nanoparticle therapy speeds healing of all sorts of wounds

An experimental therapy developed by researchers at Albert Einstein College of Medicine of Yeshiva University cut in half the time it takes to heal wounds compared to no treatment at all. Details of the therapy, which was successfully tested in mice, were published online in the Journal of Investigative Dermatology.

30 Mar 2015

Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

Nanoparticles hold great promise for cancer diagnostics and therapies, but only to the extent that they can be selectively guided to tumors and cancer cells.

30 Mar 2015

Wyatt Technology’s CG-MALS system enables characterization of complex protein-protein interactions

Study published in Nature outlines use of Wyatt’s Calypso II system to confirm the stoichiometry of αSNAP-SNARE complex

From Waters | Wyatt Technology 26 Mar 2015

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

NantWorks, Inc. and Sorrento Therapeutics, Inc., announced today that they have entered into a binding agreement to initiate a global collaboration to discover and develop novel anti-cancer immunotherapies derived from Sorrento's proprietary G-MAB library against neoepitopes of tumor-specific antigens discovered using NantWorks' proprietary pan-omics based, precision medicine approach.

16 Mar 2015

Medicine-loaded nanoparticles could help patients achieve corneal transplant success

There are about 48,000 corneal transplants done each year in the U.S., compared to approximately 16,000 kidney transplants and 2,100 heart transplants. Out of the 48,000 corneal transplants done, 10 percent of them end up in rejection, largely due to poor medication compliance. This costs the health care system and puts undue strain on clinicians, patients and their families.

12 Mar 2015

More research needed to explore toxicity of cellulose nanocrystals, says Virginia Tech scientist

Are cellulose nanocrystals harmful to human health? The answer might depend on the route of exposure, according to a review of the literature by a Virginia Tech scientist, but there have been few studies and many questions remain.

12 Mar 2015

Malvern launches two new ITC systems to support life science research

Malvern Instruments has launched two new-generation isothermal titration calorimeters (ITC), advancing its recently acquired MicroCal range to further support life science researchers studying biomolecular interactions. The new manual Malvern MicroCal PEAQ-ITC and fully automated Malvern MicroCal PEAQ-ITC Automatedsystems are designed to deliver the enhanced functionality and robust performance now demanded of this essential tool.

3 Mar 2015

New medical device could revolutionise kidney disease care in the UK

A new medical device which combines nanotechnology with a pregnancy tester could help diagnose and treat the 1 million people in the UK who don’t know they have kidney disease, a new report by the Institution of Mechanical Engineers reveals today.

26 Feb 2015

New TAU study may offer hope to people diagnosed with Glioblastoma multiforme

There are no effective available treatments for sufferers of Glioblastoma multiforme (GBM), the most aggressive and devastating form of brain tumor. The disease, always fatal, has a survival rate of only 6-18 months.

25 Feb 2015

MIT chemical engineers develop new type of self-healing hydrogel

Scientists are interested in using gels to deliver drugs because they can be molded into specific shapes and designed to release their payload over a specified time period. However, current versions aren't always practical because must be implanted surgically.

20 Feb 2015

Korean scientists produce flexible, stable monolayers of protein-bound gold nanoparticles

Free-standing nanoparticle films are of great interest for technical applications, such as the development of nanoelectronic devices. In the journal Angewandte Chemie, Korean scientists have introduced very flexible and stable monolayers of gold nanoparticles made by a self-assembly process based on protein aggregation. The films were used to coat wafers up to 10 cm in diameter.

20 Feb 2015

Targeted nanomedicines could help prevent heart attacks caused by atherosclerosis

Nanometer-sized "drones" that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis, according to a study in pre-clinical models by scientists at Brigham and Women's Hospital and Columbia University Medical Center.

19 Feb 2015

Analytical strategies that support OSD formulation: A new whitepaper from Malvern Instruments

A new whitepaper from Malvern Panalytical provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion.

From Malvern Panalytical 12 Feb 2015

Nanoparticle News and Research

Further Reading

Study points to TMPRSS2 gene as culprit for aggressive forms of androgen-fuelled cancers

Adseverin protein plays key role in bone loss associated with osteoinflammatory disease

Particle Sciences receives patent for its surface arrayed therapeutics drug delivery platform

Scientists identify small RNA molecule that can suppress cancer-causing genes in GBM

Simple test outperforms current standard test for early-stage prostate cancer

Nanoparticle technique inhibits tumor growth, prolongs survival in animal models

Biomedical researchers successfully convert microbubble technology into nanoparticles

Experimental nanoparticle therapy speeds healing of all sorts of wounds

Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

Wyatt Technology’s CG-MALS system enables characterization of complex protein-protein interactions

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

Medicine-loaded nanoparticles could help patients achieve corneal transplant success

More research needed to explore toxicity of cellulose nanocrystals, says Virginia Tech scientist

Malvern launches two new ITC systems to support life science research

New medical device could revolutionise kidney disease care in the UK

New TAU study may offer hope to people diagnosed with Glioblastoma multiforme

MIT chemical engineers develop new type of self-healing hydrogel

Korean scientists produce flexible, stable monolayers of protein-bound gold nanoparticles

Targeted nanomedicines could help prevent heart attacks caused by atherosclerosis

Analytical strategies that support OSD formulation: A new whitepaper from Malvern Instruments

How to solve the hidden bottleneck in lipid nanoparticle development eBook

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