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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Isis Pharmaceuticals awarded $1.5 million NIH grant to improve RNAi-based therapeutics

Isis Pharmaceuticals, Inc. has announced that it has been awarded a multi-year Phase 2 Small Business Innovation Research (SBIR) grant by the National Institutes of Health (NIH) for up to $1.5 million to design oligonucleotide drugs that can exploit the RNA interference (RNAi) antisense mechanism for disease treatment.

4 Oct 2007

Prostate cancer treatment may encourage spread of cancer cells

According to a new study by researchers in the U.S. the popular prostate cancer treatment, androgen deprivation therapy, may in fact encourage the spread of cancer cells throughout the body.

3 Oct 2007

Weight-based dosing of ribavirin improves outcomes for patients with hepatitis C

Patients with hepatitis C treated with combination therapy of pegylated interferon and ribavirin had better outcomes when taking a weight-based dosage of ribavirin compared to a flat dosage.

2 Oct 2007

Worm study sheds light on how the human body ages

Microscopic worms used for scientific research are living longer despite cellular defects, a discovery that is shedding light on how the human body ages and how doctors could one day limit or reverse genetic mutations that cause inherited diseases, according to a new University of Colorado at Boulder study.

2 Oct 2007

Androgen deprivation therapy for prostate cancer may encourage spread of disease

A popular prostate cancer treatment called androgen deprivation therapy may encourage prostate cancer cells to produce a protein that makes them more likely to spread throughout the body, a new study by Johns Hopkins researchers suggests.

1 Oct 2007

microRNAs may be key to HIV's ability to hide, evade drugs

Tiny pieces of genetic material called microRNA (miRNA), better known for its roles in cancer, could be a key to unlocking the secrets of how HIV, the AIDS virus, evades detection, hiding in the immune system.

1 Oct 2007

Genomic profiling of lung tumors helps doctors choose most effective treatment

Determining the genetic profile of a particular lung tumor can help clinicians make the crucial decision about which chemotherapy treatment to try first.

29 Sep 2007

Genetic sequence of Giardia complete

Giardia lamblia, one of the most common human parasites in the United States, causes more than 20,000 intestinal infections a year, often through contact with contaminated drinking or swimming water.

27 Sep 2007

Tumor cell receptor provides new therapeutic target

Working with a line of highly metastatic head and neck cancer cells, a research team at the Winship Cancer Institute and Emory University School of Medicine has found that a specific cell surface receptor present at very low levels in non-metastatic head and neck cancer cells.

27 Sep 2007

Researchers demonstrate safety of synthetic siRNAs

Researchers from MIT, Alnylam Pharmaceuticals and other institutions have demonstrated the safety of a promising type of genetic therapy that could lead to treatments for a wide range of diseases such as cancer.

27 Sep 2007

The jury is in: microRNAs can cause tumors to metastasize

These tiny molecules fine-tune protein production and play a powerful role in biological processes ranging from development to aging. Now scientists have proved that they can prompt otherwise sedentary cancer cells to move and invade other tissues.

27 Sep 2007

BioNanomatrix issued new nanofluidics patent

The patent covers a novel technique for the integration of nanofluidic channels with sample delivery systems, enabling single molecules of DNA, RNA or other proteins to be separated out from standard laboratory samples for direct imaging and analysis.

25 Sep 2007

FAU receives patent for invention that induces and restores cardiac muscle function

Florida Atlantic University received U.S. patent no. 10/822,496, "Promoting Cardiac Cell Differentiation," based on an invention which induces and restores cardiac muscle function.

24 Sep 2007

When biological molecules kiss, a new kind of biosensor can tell

A new and deceptively simple technique has been developed by chemists at Vanderbilt University that can measure the interactions between free-floating, unlabeled biological molecules including proteins, sugars, antibodies, DNA and RNA.

21 Sep 2007

New patented invention induces and restores cardiac muscle function

Florida Atlantic University received U.S. patent no. 10/822,496, "Promoting Cardiac Cell Differentiation," based on an invention which induces and restores cardiac muscle function.

21 Sep 2007

Process of necrosis redefined in landmark study

A new study led by investigators from the University of Pittsburgh School of Medicine demonstrates that the process of necrosis, long thought to be a chaotic, irreversible pathway to cell death, may actually be triggered as part of a regulated response to stress by a powerful protein, SRP-6, that can potentially halt necrosis in its path.

21 Sep 2007

Pregnancy may slow AIDS progression

A new study may help put to rest fears that pregnancy accelerates progression to full-blown AIDS in women with HIV receiving antiretroviral therapy.

20 Sep 2007

Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding

An algorithm utilizing structure mapping and thermodynamics is introduced for RNA pseudoknot prediction.

20 Sep 2007

Test for lung cancer looks for discomforting quiet among protective genes

When it is quiet – "almost too quiet" – in movies, it is a sign that something is about to go wrong for the good guys.

18 Sep 2007

Re-engineered human T cells effectively target and kill cancerous B cells

Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia (ALL), according to researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).

18 Sep 2007