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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Important new gene-silencing mechanism

Genes provide the instructions used by the individual cells to produce the many different proteins that make up the body.

17 May 2007

New findings on microRNAs

Over 30% of our genes are under the control of small molecules called microRNAs.

17 May 2007

Culture techniques can significantly affect cell growth and function

When it comes to growing cells in a lab, technique matters. A new Brown University study shows that nerve cells grown in three-dimensional cultures use 1,766 genes differently compared to nerve cells grown in standard two-dimensional petri dishes.

17 May 2007

Researchers identify human genes targeted by a virus believed to cause Kaposi's sarcoma

University of Florida researchers have identified specific human genes targeted by a virus believed to cause Kaposi's sarcoma, a rare form of cancer associated with AIDS and with organ transplants that causes patches of red or purple tissue to grow under people's skin.

11 May 2007

Researchers equip E. coli with a "riboswitch" chemo-navigational system

Using an innovative method to control the movement of Escherichia coli in a chemical environment, Emory University scientists have opened the door to powerful new opportunities in drug delivery, environmental cleanup and synthetic biology.

11 May 2007

Breakthrough on cytomegalovirus transmission

Researchers at the La Jolla Institute for Allergy & Immunology have shown that cytomegalovirus (CMV) in the salivary glands can be reduced , and in some cases eliminated , through the use of antibodies to enhance the disease-fighting power of the immune system.

11 May 2007

New understanding of ubiquitylation

It turns out there's more than one way to skin a gene. New research from Rockefeller University suggests that two closely related DNA unpackaging mechanisms may not work the way scientists thought.

10 May 2007

Researchers discover genetic 'shut down' trigger in healthy immune cells

A fundamental genetic mechanism that shuts down an important gene in healthy immune system cells has been discovered that could one day lead to new therapies against infections, leukemia and other cancers.

10 May 2007

Sigma-Aldrich acquires Molecular Medicine BioServices

Sigma-Aldrich Corporation has announced that it has acquired Molecular Medicine BioServices Inc. (MMB), a biopharmaceutical contract manufacturing organization (CMO) located in Carlsbad, California, to further enhance the biologics capabilities within its SAFC Pharma business segment.

9 May 2007

Gene-for-gene interactions help bacteria kill their host

Scientists have discovered that a cousin of the plague bacterium uses a single gene to out-fox insect immune defences and kill its host.

4 May 2007

Expression pattern of microRNA may be useful in differentiating between chronic pancreatitis and pancreatic cancer

Pancreatic cancer is a lethal disease, with the annual deaths nearly equaling the incidence of 33,000 in the United States, according to background information in the article.

2 May 2007

Zorro-LNA stops genetic disorders in their tracks

A study to appear in the June 2007 issue of The FASEB Journal describes a new agent, called "Zorro-LNA," which has the potential to stop genetic disorders in their tracks.

1 May 2007

RNA analysis can identify rejection in lung transplant patients

Recent data from the Lung Allograft Rejection Gene expression Observational (LARGO) study provides compelling evidence that profiling gene expression in peripheral blood can detect organ rejection in lung transplant patients.

1 May 2007

Unicellular microRNA discovery

In the May 15th issue of Genes & Development, an international collaboration of researchers, led by Dr. Yijun Qi (National Institute of Biological Sciences, China), report on their discovery of microRNAs in the unicellular green alga, Chlamydomonas reinhardtii.

30 Apr 2007